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CORAL GABLES, Fla., Dec. 09, 2024  -- Relmada Therapeutics, Inc. , a late-stage biotechnology company addressing diseases of the central nervous system , today announced that in light of the recent data monitoring committee  evaluation of the full dataset from the Reliance II Phase 3 study of the Company's REL-1017 program, the Company will discontinue the Reliance II and Relight Phase 3 studies. The Company will continue to advance the Phase 1 study of REL-P11, an investigational agent for the treatment of metabolic disease, currently in a Phase 1 first-in-human study.The Company has not set a timetable for completion of the evaluation process and does not intend to disclose further developments or guidance on the status of its exploration of strategic alternatives unless and until it is determined that further disclosure is appropriate or necessary.Relmada Therapeutics is a l","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RLMD","03160","BK4099","BK4588","BK4555","BK4139","BK4135","TM","CNS","BK4007","BK4585","LENZ"],"gpt_icon":0},{"id":"2489965454","title":"Relmada Shares Continue Downward Spiral After Downgrades","url":"https://stock-news.laohu8.com/highlight/detail?id=2489965454","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489965454?lang=en_us&edition=fundamental","pubTime":"2024-12-06 02:31","pubTimestamp":1733423517,"startTime":"0","endTime":"0","summary":"Relmada Therapeutics  shares continued falling on Thursday after some analysts downgraded its stock following failure in late-stage trial of anti-depressant candidate.Mizuho downgraded the stock to neutral from outperform and slashed its price target to $1 from $23, while Leerink Partners lowered its rating to market perform from outperform, also with a $1 price target.Relmada on Wednesday said that an independent data monitoring committee has determined that a late-stage study of REL-1017 as an adjunctive treatment for major depressive disorder is \"futile.\" The company will determine its next steps after assessing the full dataset.The company's stock was down nearly 16% in recent trading after falling more than 70% on Wednesday.Price: 0.53, Change: -0.10, Percent Change: -15.71","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RLMD"],"gpt_icon":0},{"id":"2489493420","title":"Mizuho Securities downgrades Relmada Therapeutics (RLMD) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2489493420","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489493420?lang=en_us&edition=fundamental","pubTime":"2024-12-06 01:55","pubTimestamp":1733421334,"startTime":"0","endTime":"0","summary":"Relmada Therapeutics (RLMD – Research Report) received a Hold rating and a $1.00 price target from Mizuho Securities analyst Uy Ear yesterday. The ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/mizuho-securities-downgrades-relmada-therapeutics-rlmd-to-a-hold?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/mizuho-securities-downgrades-relmada-therapeutics-rlmd-to-a-hold?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["MFG","RLMD"],"gpt_icon":0},{"id":"2489062459","title":"Mizuho Downgrades Relmada Therapeutics to Neutral From Outperform, Adjusts Price Target to $1 From $23","url":"https://stock-news.laohu8.com/highlight/detail?id=2489062459","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489062459?lang=en_us&edition=fundamental","pubTime":"2024-12-05 21:38","pubTimestamp":1733405896,"startTime":"0","endTime":"0","summary":"Mizuho Downgrades Relmada Therapeutics to Neutral From Outperform, Adjusts Price Target to $1 From $23","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","RLMD","MFG"],"gpt_icon":0},{"id":"2489486158","title":"Relmada Therapeutics Inc : Mizuho Cuts to Neutral From Outperform","url":"https://stock-news.laohu8.com/highlight/detail?id=2489486158","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489486158?lang=en_us&edition=fundamental","pubTime":"2024-12-05 15:46","pubTimestamp":1733384794,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241205:nFWN3N602Q:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","RLMD"],"gpt_icon":0},{"id":"2489485894","title":"U.S. RESEARCH ROUNDUP- Autozone, Costco Wholesale, Salesforce","url":"https://stock-news.laohu8.com/highlight/detail?id=2489485894","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489485894?lang=en_us&edition=fundamental","pubTime":"2024-12-05 15:19","pubTimestamp":1733383175,"startTime":"0","endTime":"0","summary":"Dec 5 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Autozone, Costco Wholesale and Salesforce on Thursday.  HIGHLIGHTS","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AZO","CRM","RLMD","PRO","GXO","COST","EW","KMX","CXM","CPB","CHPT","ASB","NCNO","CHWY","DLTR","FL","CCRN","CDMO"],"gpt_icon":1},{"id":"2489071331","title":"Relmada Therapeutics Inc : Leerink Partners Cuts Target Price to $1 From $10","url":"https://stock-news.laohu8.com/highlight/detail?id=2489071331","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489071331?lang=en_us&edition=fundamental","pubTime":"2024-12-05 14:06","pubTimestamp":1733378809,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241205:nFWN3N51WI:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RLMD","BK4007"],"gpt_icon":0},{"id":"2489103911","title":"Leerink Partners Downgrades Relmada Therapeutics to Market Perform From Outperform, $1 Price Target; Shares Plummet","url":"https://stock-news.laohu8.com/highlight/detail?id=2489103911","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489103911?lang=en_us&edition=fundamental","pubTime":"2024-12-05 01:54","pubTimestamp":1733334858,"startTime":"0","endTime":"0","summary":"Price: 0.66, Change: -2.11, Percent Change: -76.25","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RLMD","LENZ"],"gpt_icon":0},{"id":"2488118209","title":"Relmada Therapeutics Inc : Jefferies Cuts to Hold From Buy; Cuts Target Price to $0.60 From $13","url":"https://stock-news.laohu8.com/highlight/detail?id=2488118209","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488118209?lang=en_us&edition=fundamental","pubTime":"2024-12-04 23:05","pubTimestamp":1733324718,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241204:nFWN3N51GO:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","RLMD"],"gpt_icon":0},{"id":"2488719472","title":"Relmada Therapeutics Shares Down 76.5% After Analysis Shows Depression Drug Unlikely to Meet Main Goal","url":"https://stock-news.laohu8.com/highlight/detail?id=2488719472","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488719472?lang=en_us&edition=fundamental","pubTime":"2024-12-04 22:32","pubTimestamp":1733322738,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241204:nFWN3N51S5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RLMD","BK4007"],"gpt_icon":0},{"id":"2488196479","title":"Relmada Study of Major-Depression Treatment Deemed Futile; Shares Plummet - Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2488196479","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488196479?lang=en_us&edition=fundamental","pubTime":"2024-12-04 21:40","pubTimestamp":1733319600,"startTime":"0","endTime":"0","summary":"Relmada Therapeutics lost more than two-thirds of its market value early Wednesday after the biotechnology company said a treatment for major depressive disorder would likely fail to meet its primary goal in a trial it deemed futile.Shares of Relmada dropped 77% to 64 cents in premarket trading. The stock already was down by about a third since the start of the year, as of Tuesday's close.The Coral Gables, Fla., company said an interim analysis by an independent data monitoring committee found the treatment was unlikely to meet the primary endpoint with statistical significance in a Phase 3 study.The treatment, REL-1017, was being evaluated as an adjunctive treatment for major depressive disorder to be used in combination with other approved anti-depressants.Relmada said no new safety signals were reported.\"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program,\" Chief Executive Sergio Traversa said.Relmada said it will focus on ","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Relmada Study of Major-Depression Treatment Deemed Futile; Shares Plummet - Update","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","RLMD"],"gpt_icon":0},{"id":"2488219516","title":"BUZZ-Relmada Therapeutics slumps as depression drug unlikely to meet main trial goal","url":"https://stock-news.laohu8.com/highlight/detail?id=2488219516","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488219516?lang=en_us&edition=fundamental","pubTime":"2024-12-04 21:28","pubTimestamp":1733318881,"startTime":"0","endTime":"0","summary":"** Shares of drug developer Relmada Therapeutics    fall 77.6% to 62 cents premarket   ** Co says its depression treatment is \"unlikely\" to meet the main goal of a late-stage trial, according to an independent data monitoring committee's analysis   ** Co was testing the treatment, REL-1017, as an additional treatment for major depressive disorder to be used in combination with other approved anti-depressants   ** Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program - RLMD   ** Co had about $54.1 million in cash and cash equivalents as of September 30, 2024   ** Up to last close, stock down 33% YTD ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","BK4139","RLMD","LENZ"],"gpt_icon":0},{"id":"2488193627","title":"Relmada Therapeutics Shares Resume Trading Premarket, Last Down 78.7% After Co's Depression Drug Unlikely to Meet Main Trial Goal","url":"https://stock-news.laohu8.com/highlight/detail?id=2488193627","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488193627?lang=en_us&edition=fundamental","pubTime":"2024-12-04 21:06","pubTimestamp":1733317570,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241204:nL3N3N50X7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","RLMD"],"gpt_icon":0},{"id":"2488193985","title":"Relmada Therapeutics' Late-Stage Trial of REL-1017 Deemed 'Futile' -- Shares Decline Pre-Bell","url":"https://stock-news.laohu8.com/highlight/detail?id=2488193985","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488193985?lang=en_us&edition=fundamental","pubTime":"2024-12-04 21:05","pubTimestamp":1733317503,"startTime":"0","endTime":"0","summary":"Relmada Therapeutics Inc  said Wednesday that an Independent Data Monitoring Committee has determined that a late-stage study of REL-1017 as an adjunctive treatment for major depressive disorder is \"futile.\"The committee said trial is unlikely to meet the primary efficacy endpoint with statistical significance.\"We are disappointed with the outcome of this interim analysis,\" the company quoted its chief executive officer, Sergio Traversa, as saying in a statement. \"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program.\"The company's shares were down more than 70% in recent premarket activity.Price: 0.6100, Change: -2.16, Percent Change: -77.60","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","BK4139","RLMD","BK4007","SSI"],"gpt_icon":0},{"id":"2488198688","title":"Relmada Therapeutics Study of Major Depressive Disorder Treatment Assessed as Futile","url":"https://stock-news.laohu8.com/highlight/detail?id=2488198688","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488198688?lang=en_us&edition=fundamental","pubTime":"2024-12-04 20:50","pubTimestamp":1733316600,"startTime":"0","endTime":"0","summary":"Relmada Therapeutics said an interim analysis of a study assessing a treatment for major depressive disorder is futile and unlikely to meet the primary efficacy endpoint with statistical significance.The late-stage biotechnology company said an interim analysis of Reliance II conducted by the Independent Data Monitoring Committee determined its assessment of the Phase 3 study. Reliance II was designed to evaluate REL-1017 as an adjunctive treatment for major depressive disorder to be used in combination with other approved anti-depressants.Relmada said no new safety signals were reported.\"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program,\" said Chief Executive Sergio Traversa. He added that Relmada will continue to advance a Phase 1 study of REL-P11 as a treatment of metabolic disease.Trading was halted at 7:25 a.m. ET ahead of its disclosure and has yet to resume trading as of 7:47 a.m. ET.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","RLMD","BK4139","BK4007"],"gpt_icon":0}],"pageSize":16,"totalPage":4,"pageCount":2,"totalSize":50}]}}

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