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Sage Therapeutics

7.37

-0.4000-5.15%

Pre-market: 7.15-0.2200-2.99%07:30 EDT

Volume:1.01M

Turnover:7.56M

Market Cap:453.11M

PE:-1.12

High:7.68

Open:7.68

Low:7.35

Close:7.77

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Overview Company News Filings

BUZZ-Sage Therapeutics soars after Biogen makes $441.7 mln bid for company

Biogen Inc Reports 10.2% Stake in Sage Therapeutics Inc as of Jan 10, 2025

THOMSON REUTERS

Biogen Inc - Submits Non-Binding Proposal to Buy All Outstanding Shares of Sage Therapeutics' Common Stock Not Owned by Biogen for $7.22/Share in Cash

THOMSON REUTERS

Biogen Inc Says on January 10, Delivered Letter to Sage Therapeutics' CEO - SEC Filing

THOMSON REUTERS

RBC Raises Price Target on SAGE Therapeutics to $5 From $4, Keeps Sector Perform, Speculative Risk

MT Newswires Live

Wall Street Analysts Believe Sage Therapeutics (SAGE) Could Rally 42.02%: Here's is How to Trade

Sage Therapeutics Is Maintained at Overweight by Piper Sandler

Sage Therapeutics price target lowered to $9 from $26 at Piper Sandler

Sage Therapeutics (SAGE) Surges 12.2%: Is This an Indication of Further Gains?

Sage Therapeutics price target lowered to $6 from $10 at Stifel

Sage Therapeutics Is Maintained at Hold by Stifel

Sage Therapeutics Inc : Mizuho Cuts Target Price to $6 From $10

THOMSON REUTERS

Mizuho Securities Sticks to Their Hold Rating for SAGE Therapeutics (SAGE)

Biogen Stock Declines 21.4% in 3 Months: How to Play the Stock

ADVISORY-Alert wrongly tagged to Sage Therapeutics withdrawn

Sage Secures $35 Million in Series B Funding to Transform Senior Living Operations Across the U.S. and Beyond

THOMSON REUTERS

Analysts Offer Insights on Healthcare Companies: Nkarta (NKTX), Agenus (AGEN) and SAGE Therapeutics (SAGE)

Sage Therapeutics Drug's Failure in Huntington's 'Not Surprising,' RBC Says

MT Newswires Live

Biotech Stock Roundup: SAGE, INCY Suffer Setbacks, JAZZ Wins Oncology Drug Approval & More

Sage Therapeutics Is Maintained at Hold by TD Cowen

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bank","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SAGE"],"gpt_icon":0},{"id":"2501110250","title":"Wall Street Analysts Believe Sage Therapeutics (SAGE) Could Rally 42.02%: Here's is How to Trade","url":"https://stock-news.laohu8.com/highlight/detail?id=2501110250","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501110250?lang=en_us&edition=fundamental","pubTime":"2025-01-06 22:55","pubTimestamp":1736175304,"startTime":"0","endTime":"0","summary":"Sage Therapeutics, Inc.  closed the last trading session at $6.14, gaining 9.5% over the past four weeks, but there could be plenty of upside left in the stock if short-term price targets set by Wall Street analysts are any guide. The mean price target of $8.72 indicates a 42% upside potential.The average comprises 18 short-term price targets ranging from a low of $4 to a high of $17, with a standard deviation of $3.54. While the lowest estimate indicates a decline of 34.9% from the current price level, the most optimistic estimate points to a 176.9% upside. More than the range, one should note the standard deviation here, as it helps understand the variability of the estimates. The smaller the standard deviation, the greater the agreement among analysts.However, an impressive consensus price target is not the only factor that indicates a potential upside in SAGE. This view is strengthened by the agreement among analysts that the company will report better earnings than what they estim","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/wall-street-analysts-believe-sage-145504428.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","SAGE"],"gpt_icon":0},{"id":"2500979987","title":"Sage Therapeutics Is Maintained at Overweight by Piper Sandler","url":"https://stock-news.laohu8.com/highlight/detail?id=2500979987","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500979987?lang=en_us&edition=fundamental","pubTime":"2025-01-03 00:32","pubTimestamp":1735835520,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SAGE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  January 02, 2025 11:32 ET (16:32 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SAGE"],"gpt_icon":0},{"id":"2500947431","title":"Sage Therapeutics price target lowered to $9 from $26 at Piper Sandler","url":"https://stock-news.laohu8.com/highlight/detail?id=2500947431","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500947431?lang=en_us&edition=fundamental","pubTime":"2025-01-02 19:35","pubTimestamp":1735817751,"startTime":"0","endTime":"0","summary":"Piper Sandler lowered the firm’s price target on Sage Therapeutics (SAGE) to $9 from $26 and keeps an Overweight rating on the shares following a t...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/sage-therapeutics-price-target-lowered-to-9-from-26-at-piper-sandler?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/sage-therapeutics-price-target-lowered-to-9-from-26-at-piper-sandler?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SAGE"],"gpt_icon":0},{"id":"2493476480","title":"Sage Therapeutics (SAGE) Surges 12.2%: Is This an Indication of Further Gains?","url":"https://stock-news.laohu8.com/highlight/detail?id=2493476480","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493476480?lang=en_us&edition=fundamental","pubTime":"2024-12-23 21:46","pubTimestamp":1734961560,"startTime":"0","endTime":"0","summary":"Sage Therapeutics, Inc.  shares rallied 12.2% in the last trading session to close at $5.61. This move can be attributable to notable volume with a higher number of shares being traded than in a typical session. This compares to the stock's 3.1% gain over the past four weeks.The company recently announced a strategic reorganization wherein it decided to focus on the commercialization of its depression drug Zurzuvae , which is marketed in partnership with Biogen. Zurzuvae is the first and only oral treatment indicated for adults with postpartum depression. Sage Therapeutics also anticipates operating expenses to decline in 2025 compared with 2024. This might have driven the recent share price rally.For Sage Therapeutics, the consensus EPS estimate for the quarter has been revised marginally lower over the last 30 days to the current level. And a negative trend in earnings estimate revisions doesn't usually translate into price appreciation. So, make sure to keep an eye on SAGE going for","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/ev7Rs1g8mZnA8Zxoa5bA9Q--~B/aD03NTQ7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/zacks.com/72779214019151147f34c8fb2595408d","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/ev7Rs1g8mZnA8Zxoa5bA9Q--~B/aD03NTQ7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/zacks.com/72779214019151147f34c8fb2595408d"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/sage-therapeutics-sage-surges-12-134600381.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0889565916.HKD","BK4585","ASND","LU0320765992.SGD","BK4139","LU0109394709.USD","SAGE"],"gpt_icon":0},{"id":"2492577389","title":"Sage Therapeutics price target lowered to $6 from $10 at Stifel","url":"https://stock-news.laohu8.com/highlight/detail?id=2492577389","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492577389?lang=en_us&edition=fundamental","pubTime":"2024-12-17 20:20","pubTimestamp":1734438048,"startTime":"0","endTime":"0","summary":"Discover top-rated stocks from highly ranked analysts with Analyst Top Stocks!Easily identify outperforming stocks and invest smarter with Top Smart Score Stocks. RBC upgrades Sage to Sector Perform with negative thesis played out. Sage Therapeutics upgraded to Sector Perform from Underperform at RBC Capital. Sage Therapeutics reported another clinical setback, says H.C. Wainwright","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/EWL56DETwmfBFfnXlOrIoQ--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/8948b64e92d23cb05c63afbc8ed98e4c","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/EWL56DETwmfBFfnXlOrIoQ--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/8948b64e92d23cb05c63afbc8ed98e4c"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/sage-therapeutics-price-target-lowered-122048827.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/sage-therapeutics-price-target-lowered-122048827.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SAGE","SF"],"gpt_icon":0},{"id":"2491695776","title":"Sage Therapeutics Is Maintained at Hold by Stifel","url":"https://stock-news.laohu8.com/highlight/detail?id=2491695776","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491695776?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:24","pubTimestamp":1734355440,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SAGE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 16, 2024 08:24 ET (13:24 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SF","SAGE","BK4127"],"gpt_icon":0},{"id":"2490811804","title":"Sage Therapeutics Inc : Mizuho Cuts Target Price to $6 From $10","url":"https://stock-news.laohu8.com/highlight/detail?id=2490811804","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490811804?lang=en_us&edition=fundamental","pubTime":"2024-12-12 19:48","pubTimestamp":1734004114,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND0XO:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SAGE","BK4139"],"gpt_icon":0},{"id":"2490873233","title":"Mizuho Securities Sticks to Their Hold Rating for SAGE Therapeutics (SAGE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2490873233","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490873233?lang=en_us&edition=fundamental","pubTime":"2024-12-12 15:16","pubTimestamp":1733987810,"startTime":"0","endTime":"0","summary":"Mizuho Securities analyst Uy Ear maintained a Hold rating on SAGE Therapeutics (SAGE – Research Report) yesterday. The company’s shares closed yest...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/mizuho-securities-sticks-to-their-hold-rating-for-sage-therapeutics-sage-4?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/mizuho-securities-sticks-to-their-hold-rating-for-sage-therapeutics-sage-4?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SAGE","MFG"],"gpt_icon":0},{"id":"2490960048","title":"Biogen Stock Declines 21.4% in 3 Months: How to Play the Stock","url":"https://stock-news.laohu8.com/highlight/detail?id=2490960048","media":"Zacks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490960048?lang=en_us&edition=fundamental","pubTime":"2024-12-10 21:32","pubTimestamp":1733837520,"startTime":"0","endTime":"0","summary":"Biogen BIIB stock has declined 21.4% in the past three months against a decrease of 12.3% for the industry. The stock has also underperformed the sector and the S&P 500 index, as seen in the chart below.BIIB Stock Underperforms Industry, Sector & S&P 500. Sales of MS drugs and Spinraza are declining due to competitive pressure. Tecfidera revenues are declining as multiple generic versions have been launched in North America, Brazil and certain European countries. Regulatory applications seeking approval for a biosimilar referencing Tysabri have been approved in the United States and Europe. A Tysabri biosimilar is now available in some European countries, which has begun to hurt growth. Additional launches in the United States and other countries are expected in the near term. Spinraza sales declined almost 13.3% in the first nine months of 2024 due to increased competitive pressure and a decrease in demand. Sales of MS drugs and Spinraza are not expected to show any significant improv","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/vtsVt8PEmb10KQ4cnwEJfQ--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/96776645e0ac7ab203b7d5e3b37251a6","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/vtsVt8PEmb10KQ4cnwEJfQ--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/96776645e0ac7ab203b7d5e3b37251a6"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biogen-stock-declines-21-4-133200941.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0320765992.SGD","LU2089984988.USD","LLY","LU0256863902.USD","LU2361045086.USD","LU0385154629.USD","PPD","LU2089283258.USD","LU2324357040.USD","LU0314104364.USD","GB00BDT5M118.USD","BIIB","LU1064131342.USD","LU2360106947.USD","SAGE","LU2602419157.SGD","SGXZ99366536.SGD","LU1868836914.USD","LU2237443465.HKD","LU0058720904.USD","IE00BZ1G4Q59.USD","IE0002141913.USD","LU0320765059.SGD","LU0882574139.USD","LU0820561909.HKD","LU1551013342.USD","LU1989772923.USD","IE00B4R5TH58.HKD","IE00BK4W5L77.USD","LU2028103732.USD","SGXZ81514606.USD","LU2357305700.SGD","LU2237438978.USD","LU0106831901.USD","LU0096364046.USD","LU0466842654.USD","LU1868837300.USD","LU2361044949.HKD","LU2491050071.SGD","LU1623119135.USD","LU0098860793.USD","LU2023250504.SGD","LU2023251221.USD","LU0158827948.USD","LU2265009873.SGD","SG9999015952.SGD","LU1023059063.AUD","SGXZ51526630.SGD","IE0009355771.USD","LU0289739699.SGD"],"gpt_icon":1},{"id":"2489145206","title":"ADVISORY-Alert wrongly tagged to Sage Therapeutics withdrawn","url":"https://stock-news.laohu8.com/highlight/detail?id=2489145206","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489145206?lang=en_us&edition=fundamental","pubTime":"2024-12-05 22:31","pubTimestamp":1733409112,"startTime":"0","endTime":"0","summary":"ADVISORY-Alert wrongly tagged to Sage Therapeutics withdrawnAn alert on operations management platform Sage's funding round was inadvertently tagged to Sage Therapeutics SAGE.O, an unrelated company, ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241205:nTUA5RYNHH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SAGE"],"gpt_icon":0},{"id":"2489454823","title":"Sage Secures $35 Million in Series B Funding to Transform Senior Living Operations Across the U.S. and Beyond","url":"https://stock-news.laohu8.com/highlight/detail?id=2489454823","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489454823?lang=en_us&edition=fundamental","pubTime":"2024-12-05 22:00","pubTimestamp":1733407220,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241205:nTUA5RYNHH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SAGE"],"gpt_icon":0},{"id":"2486720301","title":"Analysts Offer Insights on Healthcare Companies: Nkarta (NKTX), Agenus (AGEN) and SAGE Therapeutics (SAGE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2486720301","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486720301?lang=en_us&edition=fundamental","pubTime":"2024-11-25 14:10","pubTimestamp":1732515020,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Nkarta (NKTX – Research Report), Agenus (AGEN – Research Report) ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-nkarta-nktx-agenus-agen-and-sage-therapeutics-sage?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-nkarta-nktx-agenus-agen-and-sage-therapeutics-sage?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["HCSG","SAGE","BK4505","BK4139","NKTX","AGEN","BK4137"],"gpt_icon":0},{"id":"2485475384","title":"Sage Therapeutics Drug's Failure in Huntington's 'Not Surprising,' RBC Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2485475384","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2485475384?lang=en_us&edition=fundamental","pubTime":"2024-11-22 04:16","pubTimestamp":1732220179,"startTime":"0","endTime":"0","summary":"Sage Therapeutics  drug's failure in Huntington's disease was \"not surprising\" as there was a \"low likelihood of success\" to begin with, RBC Capital Markets said in a note emailed Thursday.RBC was referring to Sage's dalzanemdor, which failed to meet the main and secondary goals in a phase 2 study called Dimension.Sage said Wednesday that the study was unable to demonstrate a statistically significant difference from baseline in subjects with cognitive impairment associated with Huntington's disease and that it was discontinuing development.RBC said it had expected the probability of success to be low given the drug's mechanism, prior data and trial endpoints. The firm added that the drug's failure, and its thesis on potential stock downside into and through the data readout had played out.With dalzanemdor no longer being developed, Sage will need to work through a \"strategic reset\" as it commercializes Zurzuvae, During this period, the company's shares should trade more in line, promp","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","SAGE"],"gpt_icon":0},{"id":"2485445105","title":"Biotech Stock Roundup: SAGE, INCY Suffer Setbacks, JAZZ Wins Oncology Drug Approval & More","url":"https://stock-news.laohu8.com/highlight/detail?id=2485445105","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2485445105?lang=en_us&edition=fundamental","pubTime":"2024-11-22 01:13","pubTimestamp":1732209180,"startTime":"0","endTime":"0","summary":"The focus shifts back to regualr pipleine updates in the biotech sector with the end of the third-quarter earnings season. Among these, Sage Therapeutics, Inc. SAGE and Incyte INCY were in focus this week as investors were disappointed with study failures.Sage Therapeutics announced disppointing top-line results from the mid-stage study on dalzanemdor . The phase II DIMENSION Study was a 12-week, double-blind, placebo-controlled study to evaluate the effects of dalzanemdor in participants with cognitive impairment  associated with Huntington’s Disease . A total of 189 participants were randomized.However, the study did not demonstrate a statistically significant difference from baseline in participants treated with dalzanemdor versus placebo on the Symbol Digit Modalities Test , a measure of cognitive function, at day 84, the primary endpoint.SAGE will also discontinue the ongoing PURVIEW Study, an open-label safety study of dalzanemdor in participants with HD.PYX-201 achieved a confir","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/1H9NqoSNLfLtMd2fyMlfBA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/9883d206905e7516b2353476e213e60c","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/1H9NqoSNLfLtMd2fyMlfBA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/9883d206905e7516b2353476e213e60c"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biotech-stock-roundup-sage-incy-171300122.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE0009355771.USD","LU0203345920.USD","BTC","IE0002270589.USD","IE0002141913.USD","LU1291159041.SGD","SG9999014542.SGD","SAGE","LU0238689110.USD","LU0965509283.SGD","SG9999001176.USD","LU0985320562.USD","INCY","IE00B19Z3581.USD","BK4588","LU1917777945.USD","LU0211331839.USD","LU1061106388.HKD","LU1989772840.SGD","LU2023250504.SGD","SG9999002224.SGD","IE00BSNM7G36.USD","LU2112291526.USD","SG9999014559.SGD","IE00BLSP4452.SGD","LU1989772923.USD","LU1093756168.USD","PYXS","SG9999002232.USD","LU1066051498.USD","LU1989771016.USD","MRK","LU2361045086.USD","LU0109394709.USD","LU1059921491.USD","LU0868494617.USD","BK4559","LU1066051811.HKD","BK4585","BK4533","IE00BJT1NW94.SGD","LU0070302665.USD","LU1093756325.SGD","LU0289739699.SGD","LU1941712348.USD","JAZZ","CI","LU1116320737.USD","LU2461242641.AUD","LU0203347892.USD"],"gpt_icon":0},{"id":"2485729412","title":"Sage Therapeutics Is Maintained at Hold by TD Cowen","url":"https://stock-news.laohu8.com/highlight/detail?id=2485729412","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2485729412?lang=en_us&edition=fundamental","pubTime":"2024-11-22 01:01","pubTimestamp":1732208460,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SAGE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 21, 2024 12:01 ET (17:01 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