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The licensed patent is based on research led by Yale University and published in Science Translational Medicine showing that treatment with simufilam appeared to meaningfully reduce seizure frequency in an animal model. Cassava will prioritize initial development efforts on tuberous sclerosis complex -related seizures. The intellectual property that Cassava has licensed is based on the promising research and development work of Angélique Bordey, PhD, Professor of Neurosurgery and Vice Chair of Research, Neurosurgery at Yale, and her collaborators. In a paper published in Science Translational Medicine2 in 2020, the researchers showed that treatment with simufilam  appeared to meaningfully reduce TSC-related seizure frequency in an an","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cassava-sciences-licenses-simufilam-method-120000627.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","BK4135","CNS","SAVA","SAVAW","BK4588","BK4547","BK4007"],"gpt_icon":0},{"id":"2513221890","title":"Cassava Gears Up to Report Q4 Earnings: What's in the Cards?","url":"https://stock-news.laohu8.com/highlight/detail?id=2513221890","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513221890?lang=en_us&edition=fundamental","pubTime":"2025-02-21 23:37","pubTimestamp":1740152220,"startTime":"0","endTime":"0","summary":"Cassava SciencesSAVA, a clinical-stage biotech focusing on developing novel products to detect and treat neurodegenerative diseases, such as Alzheimer’s disease , is expected to report fourth-quarter earnings results soon.See the ZacksEarnings Calendar to stay ahead of market-making news.The Zacks Consensus Estimate for SAVA’s loss per share in the to-be-reported quarter is currently pegged at $1.58. The company currently does not generate any revenues.Let's see how things have shaped up for the upcoming quarterly release.In the absence of a marketed product, investors are advised to look forward to the company’s pipeline updates in the upcoming earnings call.Please note that in November 2024, Cassava faced a massive setback after it reported that its lead and only pipeline drug, simufilam, failed to meet the primary endpoints in a late study for AD.Cassava beat estimates in one of the trailing four quarters and missed on the other three occasions, delivering an average negative 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100 mg for mild-to-moderate Alzheimer’s disease, named “REFOCUS-ALZ,” has been “terminated” i...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/clinical-trials-site-shows-cassava-sciences-refocus-alz-trial-terminated?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/clinical-trials-site-shows-cassava-sciences-refocus-alz-trial-terminated?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","BK4585","SAVA","BK4547","BK4588"],"gpt_icon":0},{"id":"2501747302","title":"Cassava Sciences to Reduce Staff, Halt Further Analysis","url":"https://stock-news.laohu8.com/highlight/detail?id=2501747302","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501747302?lang=en_us&edition=fundamental","pubTime":"2025-01-08 19:09","pubTimestamp":1736334591,"startTime":"0","endTime":"0","summary":"Cassava Sciences  said late Tuesday that it is reducing its workforce by ten employees, laying off 33% of its workforce in Q1, incurring one-time expenses of $400,000 for the reduction.The clinical-stage company said it will reduce expenses by halting the planned biomarker analysis of additional plasma samples from previous mid-stage studies of its investigational potential treatments for central nervous system diseases including Alzheimer's disease.The measures come after the company said a late-stage study of its drug simufilam as a potential treatment for Alzheimer's patients did not meet its 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PROVIDES A BUSINESS UPDATECASSAVA SCIENCES INC: IMPLEMENTING COST CURTAILMENT INCLUDING ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250107:nTUA4QCJDC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SAVA","BK4547","BK4588","BK4585","BK4007"],"gpt_icon":0},{"id":"2501758928","title":"Cassava Sciences Inc: in Final Stages of Discontinuing Refocus-Alz Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2501758928","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501758928?lang=en_us&edition=fundamental","pubTime":"2025-01-08 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inclu","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/01/07/3005863/8339/en/Cassava-Sciences-Provides-a-Business-Update.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","BK4547","BK4588","PET","BK4601","SAVA","BK4585","BK4192","ETH"],"gpt_icon":0},{"id":"2491779357","title":"Lost Money on Cassava Sciences, Inc.(SAVA)? Join Class Action Suit Seeking Recovery – Contact Levi & Korsinsky LLP","url":"https://stock-news.laohu8.com/highlight/detail?id=2491779357","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491779357?lang=en_us&edition=fundamental","pubTime":"2024-12-13 05:50","pubTimestamp":1734040204,"startTime":"0","endTime":"0","summary":"THE LAWSUIT: A class action securities lawsuit was filed against Cassava Sciences, Inc. (SAVA) that seeks to recover losses of Cassava Sciences, In...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/class-action/lost-money-on-cassava-sciences-inc-sava-join-class-action-suit-seeking-recovery-contact-levi-korsinsky-llp?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/class-action/lost-money-on-cassava-sciences-inc-sava-join-class-action-suit-seeking-recovery-contact-levi-korsinsky-llp?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4585","BK4547","BK4588","SAVA","BK4007"],"gpt_icon":0},{"id":"2487592243","title":"Biotech Stock Roundup: BBIO Stock Up on Drug Approval, SAVA, APLT Plunge on Setbacks & More","url":"https://stock-news.laohu8.com/highlight/detail?id=2487592243","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2487592243?lang=en_us&edition=fundamental","pubTime":"2024-11-30 02:51","pubTimestamp":1732906260,"startTime":"0","endTime":"0","summary":"Pipeline and regulatory updates are in focus in the biotech sector. Among these, BridgeBio Pharma, Inc. BBIO gained on approval of cardiovascular drug while a few others faced setbacks.BridgeBio Pharma, Inc. announced that it has obtained FDA approval for its pipeline candidate acoramidis for the treatment of adults with transthyretin amyloidosis cardiomyopathy  to reduce cardiovascular death and cardiovascular-related hospitalization. The candidate has been approved under the brand name Attruby. BBIO stock surged on the news.The FDA approval is based on positive results from the phase III ATTRibute-CM study, in which Attruby significantly reduced death and cardiovascular-related hospitalization and improved quality of life. The approval came ahead of the targeted action date of Nov. 29.MariTide caused approximately 20% average weight loss over 52 weeks without reaching a weight loss plateau. In patients with type II diabetes who were obese or overweight, the weight loss reduction was ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/0.VF5p.GUKhgU24gMni2XA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/59a827b8514d5d6d47690daa5eb16f24","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/0.VF5p.GUKhgU24gMni2XA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/59a827b8514d5d6d47690daa5eb16f24"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biotech-stock-roundup-bbio-stock-185100614.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","BK4505","IE00BJJMRZ35.SGD","BK4585","BK4547","LU0889565916.HKD","BK4533","LU1057294990.SGD","LU1983299246.USD","LU0122379950.USD","LU1061106388.HKD","LU0868494617.USD","LU2242646821.SGD","LU0320765992.SGD","IE00B2B36J28.USD","BBIO","IE0002141913.USD","LU0058720904.USD","IE00B4R5TH58.HKD","BK4534","BK4581","SG9999001440.SGD","BK4588","BK4599","IE00BJT1NW94.SGD","LU1571399168.USD","SAVAW","AMGN","BK4566","IE00BFTCPJ56.SGD","LU2112291526.USD","BK4139","SAVA","LU1023059063.AUD","LU0109394709.USD","IE0009355771.USD","LU2242652126.USD","APLT","LU0289739699.SGD"],"gpt_icon":1},{"id":"2486856869","title":"A Post-Mortem on Cassava Sciences","url":"https://stock-news.laohu8.com/highlight/detail?id=2486856869","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486856869?lang=en_us&edition=fundamental","pubTime":"2024-11-27 05:36","pubTimestamp":1732656960,"startTime":"0","endTime":"0","summary":"There are few things in the investment world scarier than owning a biotech that misses the mark. That was the case this morning with once high-flying stock Cassava Sciences . This is a stock that once skyrocketed to $146. A little over three years later, this thing closed the day at $4.30, down 83% on the day.It’s Alzheimer’s drug Simufilam did not show a significant reduction in cognitive or functional decline versus placebo in patients with mild-to-moderate Alzheimer’s disease in its Phase 3 study. The good news, if there is any, is that Cassava still has $149 million in cash as of the end of last quarter. The bad news is, they’ve got a strikeout where they were hoping to hit a home run.Moving Averages: Bartosiak starts by examining the stock's moving averages, such as the 50-day and 200-day moving averages. He points out the significance of crossovers and divergences between these averages, which can indicate potential trend changes.To read this article on Zacks.com click here.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/post-mortem-cassava-sciences-213600264.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","SAVAW","BK4547","BK4212","BK4585","SAVA","POST","BK4588"],"gpt_icon":1}],"pageSize":16,"totalPage":10,"pageCount":2,"totalSize":150}]}}