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Ltd.","value":-1.562963,"marketCap":84501613},{"symbol":"KAPA","name":"Kairos Pharma, Ltd.","value":-4.773372,"marketCap":13083812},{"symbol":"MURA","name":"Mural Oncology","value":-0.486438,"marketCap":62514088},{"symbol":"TRML","name":"Tourmaline Bio","value":-5.978414,"marketCap":437679710},{"symbol":"CTOR","name":"CITIUS ONCOLOGY INC","value":-2.294087,"marketCap":52948777},{"symbol":"INBX","name":"Inhibrx Biosciences","value":0.118522,"marketCap":204834041},{"symbol":"ORKA","name":"ORUKA THERAPEUTICS INC","value":-4.566552,"marketCap":417087281},{"symbol":"MTSR","name":"Metsera Inc.","value":-15.094245,"marketCap":2555229332},{"symbol":"NNNN","name":"Anbio Biotechnology","value":132.625406,"marketCap":298899072}]},"updateTime":1742161973672},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"STOK\",pageSize:16,pageCount:3,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2501298921","title":"Stoke Therapeutics to Host Webcast to Discuss Successful Global Regulatory Alignment for a Phase 3 Study of Zorevunersen as Potentially the First Disease Modifying Medicine for Dravet Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2501298921","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501298921?lang=en_us&edition=fundamental","pubTime":"2025-01-07 05:30","pubTimestamp":1736199000,"startTime":"0","endTime":"0","summary":"BEDFORD, Mass., January 06, 2025----Stoke Therapeutics, Inc. , a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine, today announced that its management team will host a webcast and conference call for investors and analysts to discuss successful alignment with global regulatory agencies related to a Phase 3 study of zorevunersen as potentially the first disease-modifying medicine for the treatment of Dravet syndrome.Zorevunersen is an investigational new medicine for the treatment of Dravet syndrome currently being evaluated in ongoing clinical trials. Stoke believes that zorevunersen, a proprietary antisense oligonucleotide , has the potential to be the first disease-modifying therapy to address the genetic cause of Dravet syndrome. Zorevunersen is designed to upregulate NaV1.1 protein expression by leveraging the non-mutant  copy of the SCN1A gene to restore physiological NaV1.1 levels, thereby reducing both occurrenc","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/stoke-therapeutics-host-webcast-discuss-213000848.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["HST","BK4585","STOK","BK4561","BK4139","BK4181","BK4200","BK4218","BK4588","LENZ","ASO"],"gpt_icon":0},{"id":"2494728862","title":"The Zacks Analyst Blog Highlights ADMA Biologics, Tarsus Pharmaceuticals, Stoke Therapeutics, Inc. and ChromaDex","url":"https://stock-news.laohu8.com/highlight/detail?id=2494728862","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2494728862?lang=en_us&edition=fundamental","pubTime":"2024-12-26 22:48","pubTimestamp":1735224480,"startTime":"0","endTime":"0","summary":"Chicago, IL – December 26, 2024 – Zacks.com announces the list of stocks featured in the Analyst Blog. Every day the Zacks Equity Research analysts discuss the latest news and events impacting stocks and the financial markets. Stocks recently featured in the blog include: ADMA Biologics, Inc. ADMA, Tarsus Pharmaceuticals, Inc. TARS, Stoke Therapeutics, Inc. STOK and ChromaDex Corp. CDXC.4 Drug, Biotech Stocks Up More than +50% in 2024, with Room to Grow. The biotech sector witnessed a see-saw performance in 2024. While the year started on a positive note, much of the gains slowed down in the second half of 2024. The downside in the second half was due to overall disappointing third-quarter results, guidance cuts and pipeline setbacks. The sector has declined 9.5% in the past six months, underperforming the S&P 500 index.Innovation is likely to drive growth in the industry, with key spaces like obesity and oncology drugs attracting attention. M&A activity should remain strong in 2025. O","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/zacks-analyst-blog-highlights-adma-144800374.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","STOK","BK4121","NRC","BK4139","CDXC","BK4196","TARS","ADMA"],"gpt_icon":1},{"id":"2494308570","title":"4 Drug, Biotech Stocks Rising More Than 50% in 2024 With Room to Grow","url":"https://stock-news.laohu8.com/highlight/detail?id=2494308570","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2494308570?lang=en_us&edition=fundamental","pubTime":"2024-12-25 00:49","pubTimestamp":1735058940,"startTime":"0","endTime":"0","summary":"The biotech sector witnessed a see-saw performance in 2024. While the year started on a positive note, much of the gains slowed down in the second half of 2024. The downside in the second half was due to overall disappointing third-quarter results, guidance cuts and pipeline setbacks. The sector has declined 9.5% in the past six months, underperforming the S&P 500 index, as seen in the chart below.Nonetheless, given the continuous need for innovative medicines, the biotech industry will continue to grab investors’ interest despite the inherent volatility and uncertain macroeconomic environment.Here, we discuss four biotech stocks that have returned 50% or more year to date and have room for more growth in 2025 on the back of a solid portfolio and a promising pipeline. These are ADMA Biologics, Inc. ADMA, Tarsus Pharmaceuticals, Inc. TARS, Stoke Therapeutics, Inc. STOK and ChromaDex Corporation CDXC. The stocks have outperformed the industry this year, as seen in the chart below:. Tarsu","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/sb.6qRd7FfGt7.wCjWz2vw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/675c0ae70cb5036ad2ceb9062f13afc2","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/sb.6qRd7FfGt7.wCjWz2vw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/675c0ae70cb5036ad2ceb9062f13afc2"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/4-drug-biotech-stocks-rising-164900191.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["NRC","BK4139","ADMA","BK4121","STOK","CDXC","BK4196","TARS","BK4007"],"gpt_icon":0},{"id":"2492544520","title":"Chardan Initiates Coverage on Stoke Therapeutics With Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2492544520","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492544520?lang=en_us&edition=fundamental","pubTime":"2024-12-20 21:44","pubTimestamp":1734702246,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics (STOK) has an average rating of Buy and mean price target of $22.29, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","STOK"],"gpt_icon":0},{"id":"2492411858","title":"Stoke Therapeutics initiated with a Buy at Chardan","url":"https://stock-news.laohu8.com/highlight/detail?id=2492411858","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492411858?lang=en_us&edition=fundamental","pubTime":"2024-12-20 19:40","pubTimestamp":1734694817,"startTime":"0","endTime":"0","summary":"Chardan initiated coverage of Stoke Therapeutics (STOK) with a Buy rating and $24 price target The firm cites the potential of the company’s lead a...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/stoke-therapeutics-initiated-with-a-buy-at-chardan?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/stoke-therapeutics-initiated-with-a-buy-at-chardan?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LENZ","BK4139","STOK"],"gpt_icon":0},{"id":"2492959575","title":"Companies Like Stoke Therapeutics (NASDAQ:STOK) Are In A Position To Invest In Growth","url":"https://stock-news.laohu8.com/highlight/detail?id=2492959575","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492959575?lang=en_us&edition=fundamental","pubTime":"2024-12-17 19:39","pubTimestamp":1734435560,"startTime":"0","endTime":"0","summary":"Just because a business does not make any money, does not mean that the stock will go down. Indeed, Stoke Therapeutics  stock is up 143% in the last year, providing strong gains for shareholders. But while history lauds those rare successes, those that fail are often forgotten; who remembers Pets.com?Given its strong share price performance, we think it's worthwhile for Stoke Therapeutics shareholders to consider whether its cash burn is concerning. In this report, we will consider the company's annual negative free cash flow, henceforth referring to it as the 'cash burn'. First, we'll determine its cash runway by comparing its cash burn with its cash reserves.Check out our latest analysis for Stoke Therapeutics. Does Stoke Therapeutics Have A Long Cash Runway?It may already be apparent to you that we're relatively comfortable with the way Stoke Therapeutics is burning through its cash. In particular","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/fZxxC7WFAddugsI0.C6IZw--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/2b615bb0216a492e754128412857f305","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/fZxxC7WFAddugsI0.C6IZw--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/2b615bb0216a492e754128412857f305"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/companies-stoke-therapeutics-nasdaq-stok-113920810.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TQQQ","MNQmain","NVIW.SI",".IXIC","BK4585","LU2210150020.SGD","PSQ","SQQQ","USJW.SI","STOK","QID","LU2095319765.USD","IE00B64PRP62.GBP","BK4588","NQmain","LU2210149790.SGD","USAW.SI","NDAQ","IE00B3QW5Z07.USD","IE00BKPKM429.USD","BK4139","BK4112","IE00BGHQF748.EUR","TSYW.SI","QLD"],"gpt_icon":1},{"id":"2491597793","title":"Stoke Therapeutics (NASDAQ:STOK) pulls back 9.1% this week, but still delivers shareholders solid 136% return over 1 year","url":"https://stock-news.laohu8.com/highlight/detail?id=2491597793","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491597793?lang=en_us&edition=fundamental","pubTime":"2024-12-14 22:45","pubTimestamp":1734187516,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders might be concerned after seeing the share price drop 17% in the...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/stoke-therapeutics-nasdaqstok-pulls-back-91-this-week-but-st","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["TSYW.SI","BK4139","USJW.SI","LU2210150020.SGD","STOK","IE00B3QW5Z07.USD","NQmain","QID","IE00BKPKM429.USD","PSQ","IE00BGHQF748.EUR","NDAQ","QLD","BK4112",".IXIC","IE00B64PRP62.GBP","NVIW.SI","TQQQ","BK4585","LU2210149790.SGD","MNQmain","SQQQ","BK4588","LU2095319765.USD","USAW.SI"],"gpt_icon":1},{"id":"2490953702","title":"Analysts Are Bullish on Top Healthcare Stocks: Stoke Therapeutics (STOK), Kura Oncology (KURA)","url":"https://stock-news.laohu8.com/highlight/detail?id=2490953702","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490953702?lang=en_us&edition=fundamental","pubTime":"2024-12-10 03:20","pubTimestamp":1733772010,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Stoke Therapeutics (STOK – Research Report) and Kura...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-are-bullish-on-top-healthcare-stocks-stoke-therapeutics-stok-kura-oncology-kura?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-are-bullish-on-top-healthcare-stocks-stoke-therapeutics-stok-kura-oncology-kura?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4505","HCSG","BK4137","KURA","STOK"],"gpt_icon":0},{"id":"2490236627","title":"Analysts’ Top Healthcare Picks: Stoke Therapeutics (STOK), Beam Therapeutics (BEAM)","url":"https://stock-news.laohu8.com/highlight/detail?id=2490236627","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490236627?lang=en_us&edition=fundamental","pubTime":"2024-12-09 19:30","pubTimestamp":1733743817,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Stoke Therapeutics (STOK – Research Report) and Beam...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-stoke-therapeutics-stok-beam-therapeutics-beam?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-stoke-therapeutics-stok-beam-therapeutics-beam?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4556","HCSG","STOK","BK4535","BK4585","BK4588","BK4139","BK4505","BK4137","BEAM"],"gpt_icon":0},{"id":"2489725473","title":"Stoke Therapeutics Reports Durable Seizure Control With Zorevunersen in Dravet Patient","url":"https://stock-news.laohu8.com/highlight/detail?id=2489725473","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489725473?lang=en_us&edition=fundamental","pubTime":"2024-12-07 02:06","pubTimestamp":1733508362,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics (STOK) on Friday released data from Phase 1/2a and open-label extension studies of zorevunersen for the treatment of Dravet syndrome.The data analyzed nine patients who initially re","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","STOK","LENZ"],"gpt_icon":0},{"id":"2489565802","title":"Stoke reports ‘substantial’ reductions in seizure frequency with zorevunersen","url":"https://stock-news.laohu8.com/highlight/detail?id=2489565802","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489565802?lang=en_us&edition=fundamental","pubTime":"2024-12-07 01:05","pubTimestamp":1733504730,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics (STOK) announced new data from an analysis of nine patients treated with an initial 2 or 3 doses of 70mg, followed by 45mg maint...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/stoke-reports-substantial-reductions-in-seizure-frequency-with-zorevunersen?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/stoke-reports-substantial-reductions-in-seizure-frequency-with-zorevunersen?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2489256245","title":"Stoke Therapeutics Presents New Open-Label Extension (OLE) Study Data That Further Support the Potential for Zorevunersen as a Disease-Modifying Medicine for the Treatment of Dravet Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2489256245","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489256245?lang=en_us&edition=fundamental","pubTime":"2024-12-07 01:00","pubTimestamp":1733504400,"startTime":"0","endTime":"0","summary":"Figure 1. Substantial and Durable Reductions in Convulsive Seizure Frequency from Baseline in Patients who Received 70mg zorevunersen in Phase 1/2a . Figure 2. Continuing Improvements in Vineland-3 Subdomain Growth Scale Values from OLE Baseline . – Data to be presented at the American Epilepsy Society  2024 Annual Meeting; Company to host virtual event for investors and analysts on Monday, December 9 at 8:30 am Eastern  –。\"Dravet syndrome is stressful to live with and challenging to treat. Anti-seizure medicines are helpful in reducing seizures but can only do so much for patients who continue to experience significant and life-altering limitations in many aspects of neurodevelopment and daily living,\" said Joseph Sullivan, M.D., FAES, Professor of Neurology and Pediatrics and Director of the Pediatric Epilepsy Center of Excellence at the University of California San Francisco. \"The substantial and durable reductions in seizures, as well as the continuous gains in multiple measures of","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/Ig6OzVBJFI0RSgm8Edftyw--~B/aD0yMTI7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/2b97ea6efe97cfc8056e7c1a45d67049","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/Ig6OzVBJFI0RSgm8Edftyw--~B/aD0yMTI7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/2b97ea6efe97cfc8056e7c1a45d67049"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/stoke-therapeutics-presents-open-label-170000772.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4200","IE00B7SZLL34.SGD","BK4139","BK4585","BK4588","IE00B19Z3581.USD","ASO","LENZ","LU1093756325.SGD","IE00B19Z3B42.SGD","AES","LU1093756168.USD","STOK","BK4561","BK4105","BK4519","LU0061475181.USD","IE0002270589.USD"],"gpt_icon":0},{"id":"2489995434","title":"STOK Shares Up on FDA's Breakthrough Tag for Dravet Syndrome Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2489995434","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489995434?lang=en_us&edition=fundamental","pubTime":"2024-12-05 23:13","pubTimestamp":1733411580,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics, Inc. STOK announced that the FDA has granted a Breakthrough Therapy designation to its investigational candidate, zorevunersen , for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy.Shares of the company were up 12.1% on Dec. 4 following the announcement of the news.The FDA grants breakthrough therapy designation to expedite the development and review of therapies for severe or life-threatening diseases where preliminary clinical evidence shows that the therapy may provide substantial improvements over available treatments.Zorevunersen is a novel proprietary antisense oligonucleotide with the potential to become the first disease-modifying therapy to address the genetic cause of Dravet syndrome.Year to date, shares of Stoke Therapeutics have rallied 143.5% against the industry’s decline of 8.3%.In the past 60 days, estimates for Spero Therapeutics’ 2024 loss per share have narrowed from $1.59 to $1.29. Loss per share estimates for 2025 hav","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/.WQmSb1MJO1_eLnmBVS1zA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/a1d7049b0977a02a21fd2aa02b46f307","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/.WQmSb1MJO1_eLnmBVS1zA--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/a1d7049b0977a02a21fd2aa02b46f307"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/stok-shares-fdas-breakthrough-tag-151300966.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SPRO","STOK","CSTL","BK4196","IMCR","BK4139","BK4505"],"gpt_icon":0},{"id":"2489454353","title":"GeneDx expands access to exome testing for pediatric epilepsy patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2489454353","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489454353?lang=en_us&edition=fundamental","pubTime":"2024-12-05 21:45","pubTimestamp":1733406341,"startTime":"0","endTime":"0","summary":"GeneDx (WGS) announced Biogen (BIIB), Praxis Precision Medicines (PRAX) and Stoke Therapeutics (STOK) as the founding partners to its Patient Acces...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/genedx-expands-access-to-exome-testing-for-pediatric-epilepsy-patients?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/genedx-expands-access-to-exome-testing-for-pediatric-epilepsy-patients?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4585","BK4532","BK4588","BIIB","IE00B19Z9Z06.USD","LU0109394709.USD","LU0320765992.SGD","PRAX","IE00B19Z9P08.USD","LU0234570918.USD","LU0889565916.HKD","BK4533","IE00B894F039.SGD","WGS","BK4196","STOK"],"gpt_icon":0},{"id":"2489165111","title":"BUZZ-Stoke rises on FDA's 'breakthrough therapy' tag for epileptic disorder drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2489165111","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489165111?lang=en_us&edition=fundamental","pubTime":"2024-12-05 00:50","pubTimestamp":1733331032,"startTime":"0","endTime":"0","summary":"BUZZ-Stoke rises on FDA's 'breakthrough therapy' tag for epileptic disorder drug** Shares of Stoke Therapeutics STOK.O rise 12.6% to $12.88 ** The biotech says it has received U.S. FDA's \"breakthrough therapy designation\" for zorevunersen, its experimental drug for epileptic disorder Dravet Syndrome** The FDA's tag is meant to speed up development and review of drugs to treat a serious condition or unmet medical need** Breakthrough designation seems appropriate given disease modifying potential in a field of symptomatic treatments, brokerage BTIG says** If approved, the drug could become the first disease modifying treatment for the disease** Including session's moves, stock up 143.54% YTD  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241204:nL3N3N51A2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2488193481","title":"Stoke Therapeutics' Zorevunersen Gets FDA Breakthrough Therapy Status in Dravet Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2488193481","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488193481?lang=en_us&edition=fundamental","pubTime":"2024-12-04 21:11","pubTimestamp":1733317874,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics  said Wednesday it has received Breakthrough Therapy Designation from the U.S. Food and Drug Administration for zorevunersen as treatment for Dravet syndrome with a confirmed mutation in the SCN1A gene.Phase 1/2a and open-label extension studies of zorevunersen showed \"substantial and sustained reductions in seizure frequency\" and improvements in cognitive and behavioral measures, the company said.Stoke Therapeutics said it is in talks with the FDA and other regulatory bodies about advancing to a global, randomized, controlled phase 3 study and that it will provide an update on the phase 3 registrational plans by year-end.Stoke Therapeutics shares were up over 10% in recent premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","STOK","LENZ"],"gpt_icon":0}],"pageSize":16,"totalPage":5,"pageCount":3,"totalSize":68}]}}