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Vertex Pharmaceuticals

454.96

-0.7500-0.16%

Post-market: 454.960.00000.00%19:56 EST

Volume:1.26M

Turnover:573.48M

Market Cap:115.43B

PE:31.99

High:459.05

Open:455.71

Low:452.83

Close:455.71

52wk High:519.68

52wk Low:362.50

Shares:253.72M

Float Shares:253.72M

Volume Ratio:1.03

T/O Rate:0.50%

Dividend:- -

Dividend Rate:- -

EPS(TTM):14.22

EPS(LYR):-2.0768

ROE:22.31%

ROA:12.04%

PB:6.67

PE(LYR):-219.07

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Overview Company News Filings

Vertex Pharmaceuticals announces updated data from RUBY-3 study of povetacicept

A Fresh Look at Vertex (VERX) Valuation After Q3 Earnings, Guidance Cut, and $150M Buyback

Simply Wall St.

Assessing Vertex Pharmaceuticals (VRTX) Valuation as Shares Pause After Strong Multi-Year Gains

Simply Wall St.

Vertex Presents Updated Phase 1/2 Data From Ruby-3 Study That Continue to Demonstrate Best-in-Class Potential for Povetacicept in Adults With Iga Nephropathy and Primary Membranous Nephropathy at American Society of Nephrology Kidney Week

THOMSON REUTERS

CRISPR gene therapy slashes 'bad' cholesterol, triglycerides by half in small study

Vertex Pharmaceuticals Inc. Stock Underperforms Friday When Compared To Competitors

Vertex Pharmaceuticals Is Maintained at Buy by UBS

UBS Adjusts Price Target on Vertex Pharmaceuticals to $546 From $553, Maintains Buy Rating

MT Newswires Live

CORRECTED-UPDATE 1-US FDA awards six more fast-track vouchers to speed drug reviews

BRIEF-FDA Announces Six Additional Awardees Under The CNPV Pilot Program

Entrada Therapeutics Unveils Pipeline Progress and Clinical Milestones for Neuromuscular Disease Therapies

Vertex Is Maintained at Buy by Goldman Sachs

Vortex Energy Corp. Advances Hydrogen Storage Research at Canadian Convention

Analysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX), Agilon Health (AGL) and REPRO-MED Systems (KRMD)

Evercore ISI Sticks to Their Buy Rating for Vertex Pharmaceuticals (VRTX)

Vertex Pharmaceuticals Q3 2025 Earnings Call Highlights

Vertex Pharmaceuticals Inc. Stock Underperforms Tuesday When Compared To Competitors

Stock Track | Vertex Pharmaceuticals Plummets 5.27% Following Mixed Q3 Results and Analyst Downgrades

Vertex Pharmaceuticals: Promising IgAN Market Position with Povetacicept’s Superior Efficacy and Patient-Friendly Administration

Morgan Stanley Keeps Their Hold Rating on Vertex Pharmaceuticals (VRTX)

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Cloud revenue jumped, but customer bankruptcies and faster migrations prompted management to lower Q4 guidance.\nSee our latest analysis for Vertex.\nAfter a sharp drop in the past month, which includes a 21.3% one-month share price decline and a year-to-date slide of over 63%, Vertex is searching for stability as investors digest cautious guidance,...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/8041000-choice2-main-header/1585186556238","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/8041000-choice2-main-header/1585186556238"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/software/nasdaq-verx/vertex/news/a-fresh-look-at-vertex-verx-valuation-after-q3-earnings-guid","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/software/nasdaq-verx/vertex/news/a-fresh-look-at-vertex-verx-valuation-after-q3-earnings-guid","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["VERX","VRTX"],"gpt_icon":0},{"id":"2582895143","title":"Assessing Vertex Pharmaceuticals (VRTX) Valuation as Shares Pause After Strong Multi-Year Gains","url":"https://stock-news.laohu8.com/highlight/detail?id=2582895143","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582895143?lang=en_us&edition=fundamental","pubTime":"2025-11-09 13:23","pubTimestamp":1762665829,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals (VRTX) shares have been moving in a fairly tight range recently, leaving investors wondering what the next catalyst might be. Despite subdued short-term returns, the company’s longer-term growth trends help frame the outlook for its stock.\nSee our latest analysis for Vertex Pharmaceuticals.\nAfter a steady climb earlier this year, Vertex Pharmaceuticals' share price has recently pulled back, reflecting a pause in momentum even as the company continues to report 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Pharmaceuticals Inc. Stock Underperforms Friday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2581367834","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581367834?lang=en_us&edition=fundamental","pubTime":"2025-11-08 05:40","pubTimestamp":1762551600,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Vertex Pharmaceuticals Inc.  shed 1.63% to $409.47 Friday, on what proved to be an all-around favorable trading session for the stock market, with the S&P 500 Index  rising 0.13% to 6,728.80 and the Dow Jones Industrial Average  rising 0.16% to 46,987.10.This was the stock's fourth consecutive day of losses.Vertex Pharmaceuticals Inc. closed 21.24% short of its 52-week high of $519.88, which the company reached on November 8th.The stock underperformed when compared to some of its competitors Friday, as AbbVie Inc.  rose 0.05% to $219.16, Krystal Biotech Inc.  fell 1.02% to $197.93, and Arcturus Therapeutics Holdings Inc.  rose 5.19% to $8.72.Trading volume  remained 156,878 below its 50-day average volume of 1.5 M.Data source: Dow Jones Market Data, FactSet. Data compiled November 7, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VERX","VRTX"],"gpt_icon":0},{"id":"2581833284","title":"Vertex Pharmaceuticals Is Maintained at Buy by UBS","url":"https://stock-news.laohu8.com/highlight/detail?id=2581833284","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581833284?lang=en_us&edition=fundamental","pubTime":"2025-11-08 02:33","pubTimestamp":1762540380,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/VRTX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 07, 2025 13:33 ET (18:33 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VRTX","VERX"],"gpt_icon":0},{"id":"2581884736","title":"UBS Adjusts Price Target on Vertex Pharmaceuticals to $546 From $553, Maintains Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2581884736","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581884736?lang=en_us&edition=fundamental","pubTime":"2025-11-07 23:13","pubTimestamp":1762528392,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals (VRTX) has an 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The company expects to have four clinical-stage programs by the end of 2025, with key data readouts anticipated in 2026 for ENTR-601-44 and ENTR-601-45. Phase 1/2 multiple ascending dose  study patient data for ENTR-601-44 is expected in the second quarter of 2026, while similar data for ENTR-601-45 is anticipated in mid-2026. ENTR-601-50 is set to begin a Phase 1/2 MAD study in the UK, with an EU regulatory filing expected in the second half of 2026. Additionally, Vertex Pharmaceuticals is progressing VX-670 for myotonic dystrophy type 1  in collaboration with Entrada, with completion of MAD patient enrollment and dosing targeted for the first half of 2026. Entrada also reports a cash balance of approximately $327 million, projecting a cash runway into the third quarter of 2027. You can access the full presentation through the link below.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251106:nNDL4rCWbV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0061475181.USD","TRDA","BK4585","IE00B19Z9P08.USD","LU0889565916.HKD","IE00B2B36J28.USD","LU1778281490.HKD","IE0002141913.USD","SG9999001176.USD","LU2417539215.USD","LU0823416689.USD","IE0002270589.USD","IE00B19Z9Z06.USD","BK4533","LU1035775433.USD","LU2362540622.SGD","LU0058720904.USD","LU2362541513.USD","LU2462157665.USD","SG9999013999.USD","LU0109394709.USD","LU2362541273.HKD","LU1674673428.USD","VRTX","LU0256863811.USD","LU1430594728.SGD","BK4532","SG9999001176.SGD","LU1674673691.USD","SGXZ57979304.SGD","LU2236285917.USD","BK4567","IE00B894F039.SGD","LU0432979614.USD","LU0320765992.SGD","BK4139","IE0009355771.USD","LU0234570918.USD","LU1069344957.HKD","IE00B4R5TH58.HKD","LU1093756168.USD","LU2324357040.USD","LU2237438978.USD","BK4588","IE00B19Z3B42.SGD","IE00BJT1NW94.SGD","LU0289739699.SGD","IE00BZ9MQY76.HKD","LU1093756325.SGD","LU1585245621.USD"],"gpt_icon":0},{"id":"2581777105","title":"Vertex Is Maintained at Buy by Goldman Sachs","url":"https://stock-news.laohu8.com/highlight/detail?id=2581777105","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581777105?lang=en_us&edition=fundamental","pubTime":"2025-11-06 01:15","pubTimestamp":1762362900,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/VERX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 05, 2025 12:15 ET (17:15 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VERX","VRTX"],"gpt_icon":0},{"id":"2581777082","title":"Vortex Energy Corp. 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Vortex Energy Corp. has announced the submission of an abstract by the U...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/vortex-energy-corp-advances-hydrogen-storage-research-at-canadian-convention?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/vortex-energy-corp-advances-hydrogen-storage-research-at-canadian-convention?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU2462157665.USD","LU2236285917.USD","LU0889565916.HKD","BK4533","LU2237438978.USD","LU2362541513.USD","IE00B19Z9P08.USD","LU0061475181.USD","LU2362540622.SGD","BK4567","BK4588","IE00B2B36J28.USD","IE0002141913.USD","IE0002270589.USD","IE00B19Z9Z06.USD","LU1093756168.USD","LU0079474960.USD","IE00B19Z3581.USD","LU0289739699.SGD","LU0256863811.USD","LU2456880835.USD","SG9999001176.USD","LU2362541273.HKD","LU0823416689.USD","LU0432979614.USD","LU1430594728.SGD","LU0417517546.SGD","LU1674673691.USD","LU1093756325.SGD","IE0009355771.USD","LU0109394709.USD","BK4139","IE00BZ9MQY76.HKD","LU2324357040.USD","LU1674673428.USD","SGXZ57979304.SGD","SG9999001176.SGD","LU1069344957.HKD","LU2417539215.USD","LU0234570918.USD","LU1035775433.USD","IE00BJJMRZ35.SGD","LU1585245621.USD","IE00BFTCPJ56.SGD","BK4585","VRTX","LU0058720904.USD","LU1778281490.HKD","IE00B894F039.SGD","IE00BJT1NW94.SGD"],"gpt_icon":0},{"id":"2581772626","title":"Analysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX), Agilon Health (AGL) and REPRO-MED Systems (KRMD)","url":"https://stock-news.laohu8.com/highlight/detail?id=2581772626","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581772626?lang=en_us&edition=fundamental","pubTime":"2025-11-06 00:40","pubTimestamp":1762360817,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on Vertex Pharmaceuticals (VRTX – Research Report), A...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-vertex-pharmaceuticals-vrtx-agilon-health-agl-and-repro-med-systems-krmd-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-vertex-pharmaceuticals-vrtx-agilon-health-agl-and-repro-med-systems-krmd-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4581","BK4532","LABU","XBI","MED","LU0823416689.USD","LU2236285917.USD","LU0061475181.USD","BK4023","LU1674673691.USD","KRMD","LU0889565916.HKD","LU1035775433.USD","LU1815336091.USD","SGXZ57979304.SGD","LU1093756168.USD","BK4533","AGL","BK4137","IE0002141913.USD","LU1778281490.HKD","IE00B19Z9P08.USD","BK4139","LU0058720904.USD","HCSG","LU0128526141.USD","LU1093756325.SGD","LU2237438978.USD","LU0109394709.USD","BK4183","LU2324357040.USD","SG9999013999.USD","IE0002270589.USD","IE00B19Z3B42.SGD","LU1069344957.HKD","IE00B2B36J28.USD","IE00BJJMRZ35.SGD","LU0432979614.USD","IE00B19Z3581.USD","LU1430594728.SGD","BK4588","VRTX","SG9999001176.USD","LU0029874061.USD","VERX","BK4567","LU2362540622.SGD","IE00B894F039.SGD","XLV","LU2362541273.HKD"],"gpt_icon":0},{"id":"2581712283","title":"Evercore ISI Sticks to Their Buy Rating for Vertex Pharmaceuticals (VRTX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2581712283","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581712283?lang=en_us&edition=fundamental","pubTime":"2025-11-05 14:16","pubTimestamp":1762323379,"startTime":"0","endTime":"0","summary":"In a report released yesterday, Cory Kasimov from Evercore ISI maintained a Buy rating on Vertex Pharmaceuticals, with a price target of $475.00. T...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/evercore-isi-sticks-to-their-buy-rating-for-vertex-pharmaceuticals-vrtx-blurbs-3?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/evercore-isi-sticks-to-their-buy-rating-for-vertex-pharmaceuticals-vrtx-blurbs-3?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VERX","VRTX"],"gpt_icon":0},{"id":"2581791306","title":"Vertex Pharmaceuticals Q3 2025 Earnings Call Highlights","url":"https://stock-news.laohu8.com/highlight/detail?id=2581791306","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581791306?lang=en_us&edition=fundamental","pubTime":"2025-11-05 08:11","pubTimestamp":1762301475,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals Inc. 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Vertex Pharmaceuticals’ earnings ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/vertex-pharmaceuticals-q3-2025-earnings-call-highlights?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/vertex-pharmaceuticals-q3-2025-earnings-call-highlights?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VRTX","VERX"],"gpt_icon":0},{"id":"2581767681","title":"Vertex Pharmaceuticals Inc. Stock Underperforms Tuesday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2581767681","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581767681?lang=en_us&edition=fundamental","pubTime":"2025-11-05 05:39","pubTimestamp":1762292340,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Vertex Pharmaceuticals Inc.  slid 1.02% to $421.67 Tuesday, on what proved to be an all-around grim trading session for the stock market, with the S&P 500 Index  falling 1.17% to 6,771.55 and Dow Jones Industrial Average  falling 0.53% to 47,085.24.The stock's fall snapped a three-day winning streak.Vertex Pharmaceuticals Inc. closed 18.89% below its 52-week high of $519.88, which the company achieved on November 8th.The stock demonstrated a mixed performance when compared to some of its competitors Tuesday, as AbbVie Inc.  rose 1.85% to $215.89, Krystal Biotech Inc.  rose 2.73% to $203.26, and Arcturus Therapeutics Holdings Inc.  fell 3.98% to $8.93.Data source: Dow Jones Market Data, FactSet. Data compiled November 4, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. 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