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Published first on TheFly – the ultim...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/vertex-pharmaceuticals-upgraded-to-hold-from-sell-at-canaccord?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/vertex-pharmaceuticals-upgraded-to-hold-from-sell-at-canaccord?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VRTX","VERX"],"gpt_icon":0},{"id":"2510377053","title":"BUZZ-Vertex falls after Q4 profit, sales of gene therapy disappoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2510377053","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510377053?lang=en_us&edition=fundamental","pubTime":"2025-02-12 01:32","pubTimestamp":1739295152,"startTime":"0","endTime":"0","summary":"BUZZ-Vertex falls after Q4 profit, sales of gene therapy disappoint** Shares of drugmaker Vertex Pharmaceuticals VRTX.O fall 1.8% to $461 in morning trade ** Co on Monday reported Q4 profit of $3.98/s","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250211:nL4N3P21CW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VRTX"],"gpt_icon":0},{"id":"2510337969","title":"VRTX's Q4 Earnings Miss Mark, Revenues Beat on Higher Product Sales","url":"https://stock-news.laohu8.com/highlight/detail?id=2510337969","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510337969?lang=en_us&edition=fundamental","pubTime":"2025-02-12 00:00","pubTimestamp":1739289600,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals Incorporated VRTX reported adjusted earnings of $3.98 per share for the fourth quarter of 2024, missing the Zacks Consensus Estimate of $3.99. The bottom line declined 5.2% on a year-over-year basis.See the ZacksEarnings Calendarto stay ahead of market-making news.The company reported total revenues of $2.91 billion for the fourth quarter, comprising cystic fibrosis  product revenues. The figure beat the Zacks Consensus Estimate of $2.77 billion. Total revenues rose 16% year over year, primarily driven by higher sales of Trikafta/Kaftrio .The company currently markets four CF products, Trikafta/Kaftrio, Symdeko , Orkambi and Kalydeco.Sales from other CF products increased 3.7% year over year to $191.2 million. In recent quarters, sales of other CF products have been negatively impacted as more patients switched to Trikafta.While CF remains the main area of focus, Vertex has seen rapid success in its non-CF pipeline candidates’ development in the past year. 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A copy of the letter can be downloaded here. For the second consecutive year, U.S. equity indices ended the year with double-digit returns after generating modest returns in the fourth quarter of 2024. Conestoga's investment plans were hindered by the enthusiasm for everything artificial intelligence  related, which the firm believes led to a more speculative investing climate. The Conestoga Small Cap Composite surged 1.67%  in the fourth quarter compared to the Russell 2000 Growth Index’s 1.70% return. The Conestoga SMid Cap Composite returned -0.68%  trailing the Russell 2500 Growth Index’s 2.43% return. The Conestoga Micro Cap Composite advanced 9.91%  vs the Russell Microcap Growth Index’s return of 11.55%. Finally, the Conestoga Mid Cap Composite returned -4.63%  underperforming the Russell Midcap Growth Index’s 8.14% return. Please check the top 5 holdings of the fund for a 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The c...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/vertex-pharmaceuticals-price-target-raised-to-450-from-433-at-scotiabank?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/vertex-pharmaceuticals-price-target-raised-to-450-from-433-at-scotiabank?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VRTX","VERX"],"gpt_icon":0},{"id":"2510380731","title":"Vertex Pharmaceuticals price target raised to $520 from $460 at Truist","url":"https://stock-news.laohu8.com/highlight/detail?id=2510380731","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510380731?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:41","pubTimestamp":1739284861,"startTime":"0","endTime":"0","summary":"Truist raised the firm’s price target on Vertex Pharmaceuticals (VRTX) to $520 from $460 and keeps a Buy rating on the shares. 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