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Avutometinib is an RAF/MEK clamp, while defactinib is a best-in-class selective FAK inhibitor.In the past three months, shares of Verastem have surged 86.6% against the industry’s 9.5% decline.More on the FDA Acceptance of Avutometinib NDA for LGSOC. At present, there are no FDA-approved treatments specifically for LGSOC, a rare and distinct type of ovarian cancer with unique biology and treatment responses compared to high-grade serous ovarian cancer, representing a huge unmet medical need. Per Verastem, an estimated 6,000-8,000 women in theUnited Statesand 80,000 worldwide suffer from this disease. The standard of care treatment includes hormone therapy and chemotherapy.Currently, the company is enrolling patients with recurrent LGSOC regardless of KRAS mutation status in the global phase III RAMP 301 study, which is expected to serve as a confirmatory study for the initial indica","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/vstm-nda-ovarian-cancer-combo-145600394.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX","CSTL","BK4196","BK4139","VSTM","SPRO"],"gpt_icon":0},{"id":"2500064962","title":"Verastem Shares Soar on FDA Priority Review of Cancer Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2500064962","media":"Dow Jones","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500064962?lang=en_us&edition=fundamental","pubTime":"2025-01-01 03:00","pubTimestamp":1735671600,"startTime":"0","endTime":"0","summary":"Shares of Verastem surged after the company's new cancer treatment got priority review from regulators.The stock was up 46% at $5.37 on Tuesday. Shares are still down 35% since the start of the year.The company said after the bell on Monday that the Food and Drug Administration has given priority review to its treatment for recurrent low-grade serous ovarian cancer.The FDA's decision is expected by June 30, 2025. If approved, it would be the first treatment specifically for this type of cancer, the company said.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2500460746","title":"Sector Update: Health Care Stocks Lower in Afternoon Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2500460746","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500460746?lang=en_us&edition=fundamental","pubTime":"2025-01-01 02:51","pubTimestamp":1735671116,"startTime":"0","endTime":"0","summary":"Health care stocks fell Tuesday afternoon with the NYSE Health Care Index down 0.2% and the Health Care Select Sector SPDR Fund  easing 0.1%.The iShares Biotechnology ETF  rose 0.1%.In corporate news, Verastem  shares jumped 46% after the US Food and Drug Administration accepted and granted priority review to a new drug application for its ovarian cancer drug and set an action date of June 30.Kazia Therapeutics  shares fell 37% after the company said it was considering options for its drug candidate paxalisib after the US Food and Drug Administration discouraged an accelerated approval process for the potential glioblastoma treatment.Sangamo Therapeutics  shares sank 55% after it said its partner Pfizer  decided not to proceed with further development of a new gene therapy to treat hemophilia A, a bleeding disorder.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU1066053197.SGD","XLV","BK7095","SG9999001176.USD","LU1066051498.USD","LU0170899867.USD","IE000M9KFDE8.USD","KZIA","IE00BBT3K403.USD","BK4556","IE00B19Z3581.USD","BK4599","LU0058720904.USD","LU0868494617.USD","BK4007","SG9999002232.USD","LU0122379950.USD","BK4534","LU1057294990.SGD","IBB","SG9999003800.SGD","BK4585","BK4588","SG9999013999.USD","VSTM","BK4568","IE0002270589.USD","BK4550","LU0225771236.USD","PFE.AU","BK4592","BK4533","SG9999001176.SGD","PFE","LU1883839398.USD","LU1894683264.USD","LU0234572021.USD","LU0306807586.USD","LU0225284248.USD","IE00B19Z3B42.SGD","SGXZ57979304.SGD","BK4139","IE00BLSP4452.SGD","LU0321505439.SGD","IE00BLSP4239.USD","SG9999002224.SGD","SG9999011175.SGD","SGMO","LU0321505868.SGD","LU0985481810.HKD"],"gpt_icon":1},{"id":"2500430306","title":"US Equity Indexes Decline After Midday Tuesday as 2024 Draws to Close","url":"https://stock-news.laohu8.com/highlight/detail?id=2500430306","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500430306?lang=en_us&edition=fundamental","pubTime":"2025-01-01 02:05","pubTimestamp":1735668315,"startTime":"0","endTime":"0","summary":"US benchmark stock indexes fell after midday Tuesday, continuing the previous session's losses on the last trading day of 2024.The Nasdaq slipped 0.9% to 19,314, the S&P 500 lost 0.6% to 5,874 and the","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SGMO","NVIW.SI","SG9999017495.SGD","LU2361044865.SGD","PFE.AU","LU0724617625.USD","LU1145028129.USD","LU1935043023.USD","LU0127658192.USD","AMZN","LU0943347566.SGD","IE00BK4W5L77.USD","LU2756315318.SGD","AFBI",".DJI","VSTM","PFE","LU1084165304.USD","UDOW","LU1057294990.SGD","PSQ","LU2247934214.USD","SDOW","QID","IE00B5949003.HKD","TSYW.SI",".SPX","DDM","LU0708995401.HKD","LU1201861165.SGD","TQQQ","DOG","SQQQ","LU0061474705.USD","LU0823421416.USD","USAW.SI","USJW.SI","NQmain",".IXIC","MNQmain","BK4503","EQR","LU2237957902.USD","DXD","DJX","IE00B19Z8W00.USD","IE00BBT3K403.USD","QLD","LU2463028550.USD"],"gpt_icon":1},{"id":"2495611751","title":"Verastem Shares Surge Over 24% on FDA Acceptance of Cancer Therapy Application","url":"https://stock-news.laohu8.com/highlight/detail?id=2495611751","media":"GuruFocus.com","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495611751?lang=en_us&edition=fundamental","pubTime":"2024-12-31 23:33","pubTimestamp":1735659209,"startTime":"0","endTime":"0","summary":"Following news that the U.S. Food and Drug Administration approved its New Drug Application for avutometinib in combination with defactinib to treat recurrent low-grade serous ovarian cancer in patients with KRAS mutations, Verastem Inc.  jumped 24.8% to $4.58. Setting a Prescription Drug User Fee Act action deadline of June 30, 2025, the FDA granted Priority Review, Verastem stated in a statement.GuruFocus has detected 5 Warning Signs with VSTM.Should approval be granted, the treatmentwhich is the first FDA-approved one expressly aimed at adults with recurrent KRAS mutant LGSOCwould Based on information from the Phase 2 RAMP 201 study, which showed notable response rates and tolerability for the combination treatment, the firm said, the application expands on data.With few therapeutic choices, LGSOC is an uncommon kind of ovarian cancer afflicting between 6,0008,000 women in the United States. Verastem underlined the ability of the treatment to solve this unmet medical need.Verastem h","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/verastem-shares-surge-over-24-153329366.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Verastem Shares Surge Over 24% on FDA Acceptance of Cancer Therapy Application","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["VSTM","BK4139"],"gpt_icon":0},{"id":"2495240613","title":"Verastem Shares up 32% After FDA Grants Priority Review for Ovarian Cancer Combo Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2495240613","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495240613?lang=en_us&edition=fundamental","pubTime":"2024-12-31 22:31","pubTimestamp":1735655503,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241231:nL4N3NW0JW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2495622618","title":"Traders Cautious as 2024 Draws to Close, Stifling US Equity Futures Pre-Bell","url":"https://stock-news.laohu8.com/highlight/detail?id=2495622618","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495622618?lang=en_us&edition=fundamental","pubTime":"2024-12-31 22:03","pubTimestamp":1735653835,"startTime":"0","endTime":"0","summary":"US equity futures were cautiously higher ahead of Tuesday's opening bell as traders refrained from making big bets on the last trading day of 2024.Dow Jones Industrial Average futures gained 0.2%, S&P 500 futures increased 0.3%, and Nasdaq futures were also up 0.3%.US markets will be closed on Wednesday for the New Year holiday.Oil prices were little changed, with front-month global benchmark North Sea Brent crude down 0.03% at $73.97 per barrel and US West Texas Intermediate crude flatlined at around $71 per barrel.The Case-Shiller Home Price Index is due for release at 9 am ET.In other world markets, Hong Kong's Hang Seng ended 0.1% higher, China's Shanghai Composite finished 1.6% lower, and the UK's FTSE 100 closed 0.6% higher in a holiday-shortened session. Meanwhile, the Japanese and German markets were closed for holiday.In equities, Verastem  shares were up 29% pre-bell after the company said Monday that the US Food and Drug Administration accepted for review and granted a prior","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NVIW.SI","BK4588","AFBI",".DJI","VSTM","UDOW","PSQ","BK4211","SDOW","QID","TSYW.SI",".SPX","DDM","TQQQ","DOG","SQQQ","USAW.SI","BK4139","NQmain","BK4215","USJW.SI",".IXIC","MNQmain","EQR","DXD","DJX","BK4585","QLD"],"gpt_icon":1},{"id":"2495161388","title":"Morning Movers: EHang jumps following guidance raise","url":"https://stock-news.laohu8.com/highlight/detail?id=2495161388","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495161388?lang=en_us&edition=fundamental","pubTime":"2024-12-31 21:55","pubTimestamp":1735653319,"startTime":"0","endTime":"0","summary":"Check out this morning’s top movers from around Wall Street, compiled by The Fly. HIGHER – Verastem (VSTM) up 29% after announcing that the FDA has...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/morning-movers-ehang-jumps-following-guidance-raise?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/morning-movers-ehang-jumps-following-guidance-raise?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VSTM","BK4139"],"gpt_icon":0},{"id":"2495669477","title":"Verastem Shares up 27.5% Premarket After FDA Grants Priority Review for Ovarian Cancer Combo 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Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495691214?lang=en_us&edition=fundamental","pubTime":"2024-12-31 20:35","pubTimestamp":1735648556,"startTime":"0","endTime":"0","summary":"Aptorum Group  shares increased more than fourfold pre-bell Tuesday, adding to Monday's gains.VerifyMe  shares surged 192% following a 6% increase from the previous session.Verastem  shares rose 37% after the company said Monday that the US Food and Drug Administration accepted for review and granted a priority review status to the company's new drug application for an ovarian cancer drug combination.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7057","BK4157","VSTM","APM","APM.AU","BK4139","VRME"],"gpt_icon":0},{"id":"2495271699","title":"BUZZ-Verastem jumps as FDA grants priority review for ovarian cancer combo therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2495271699","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495271699?lang=en_us&edition=fundamental","pubTime":"2024-12-31 20:16","pubTimestamp":1735647386,"startTime":"0","endTime":"0","summary":"BUZZ-Verastem jumps as FDA grants priority review for ovarian cancer combo therapy** Shares of cancer drugmaker Verastem VSTM.O rise 45.7% to $5.35 premarket** On Monday, VSTM said the U.S. FDA grante","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241231:nL4N3NW0F8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2495693701","title":"BTIG Raises Price Target on Verastem to $20 From $13, Keeps Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2495693701","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495693701?lang=en_us&edition=fundamental","pubTime":"2024-12-31 19:28","pubTimestamp":1735644502,"startTime":"0","endTime":"0","summary":"Verastem (VSTM)  has an average rating of buy and mean price target of $11.86, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks and","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["VSTM"],"gpt_icon":0},{"id":"2495674526","title":"Verastem price target raised to $20 from $13 at BTIG","url":"https://stock-news.laohu8.com/highlight/detail?id=2495674526","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495674526?lang=en_us&edition=fundamental","pubTime":"2024-12-31 18:20","pubTimestamp":1735640410,"startTime":"0","endTime":"0","summary":"BTIG raised the firm’s price target on Verastem (VSTM) to $20 from $13 and keeps a Buy rating on the shares after the company announced the FDA acc...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/verastem-price-target-raised-to-20-from-13-at-btig?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/verastem-price-target-raised-to-20-from-13-at-btig?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VSTM"],"gpt_icon":0},{"id":"2495650629","title":"U.S. RESEARCH ROUNDUP- Axsome Therapeutics, Ducommun, Vacasa","url":"https://stock-news.laohu8.com/highlight/detail?id=2495650629","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495650629?lang=en_us&edition=fundamental","pubTime":"2024-12-31 16:08","pubTimestamp":1735632504,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP- Axsome Therapeutics, Ducommun, VacasaDec 31  - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Axsome Therapeutics, Ducommun and Vacasa on Tuesday. HIGHLIGHTS* Axsome Therapeutics Inc AXSM.O: Needham raises target price to $133 from $130* Ducommun Inc DCO.N: RBC reinstates coverage with outperform rating* Vacasa Inc VCSA.O: Needham cuts to hold from buyFollowing is a summary of research actions on U.S. companies reported by Reuters on Tuesday. Stock entries are in alphabetical order. * Axsome Therapeutics Inc AXSM.O: Needham raises target price to $133 from $130* Axsome Therapeutics Inc AXSM.O: RBC raises target price to $138 from $132* Cal-Maine Foods Inc CALM.O: Stephens raises target price to $88 from $82* Ducommun Inc DCO.N: RBC reinstates coverage with outperform rating* Ducommun Inc DCO.N: RBC reinstates coverage with price target $72 vs $60* Marinus Pharmaceuticals Inc MRNS.O: Baird raises","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241231:nL4N3NW0B2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VCSA","BK4142","IE00B19Z4B17.USD","IE0031619046.USD","BK4539","MRNS","BK4007","IE00B7SZL793.SGD","AXSM","DCO","BK4212","BK4187","BK4585","CALM","BK4588","IE00B66KJ199.SGD","BK4505","VSTM","BK4139"],"gpt_icon":0},{"id":"2495343596","title":"Verastem Inc : Btig Raises Target Price to $20 From $13","url":"https://stock-news.laohu8.com/highlight/detail?id=2495343596","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495343596?lang=en_us&edition=fundamental","pubTime":"2024-12-31 12:24","pubTimestamp":1735619045,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241231:nFWN3NV019:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["VSTM","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":8,"pageCount":4,"totalSize":121}]}}