三叶草生物(02197.HK)二价RSV候选疫苗与GSKRSV疫苗头对头比较在老年人受试者中获积极临床数据

阿斯达克财经

2024/10/29

三叶草生物(02197.HK) 公布，在Ⅰ期临床试验中评估未使用佐剂的二价RSV PreF－三聚体亚单位候选疫苗SCB-1019 (开发基于三叶草生物独有的Trimer-Tag－蛋白质三聚体化疫苗技术平台)与GSK使用AS01E佐剂的RSV疫苗AREXVY进行头对头比较后，在老年人受试者中获得更多积极的免疫原性和安全性数据。与GSK使用AS01E佐剂的RSV疫苗AREXVY(76.7%)相比，未...

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HK) bivalent RSV vaccine candidate and GSKRSV vaccine has obtained positive clinical data in elderly subjects","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"159646":1,"02197":1},"content_text":"三叶草生物(02197.HK) 公布，在Ⅰ期临床试验中评估未使用佐剂的二价RSV PreF－三聚体亚单位候选疫苗SCB-1019 (开发基于三叶草生物独有的Trimer-Tag－蛋白质三聚体化疫苗技术平台)与GSK使用AS01E佐剂的RSV疫苗AREXVY进行头对头比较后，在老年人受试者中获得更多积极的免疫原性和安全性数据。与GSK使用AS01E佐剂的RSV疫苗AREXVY(76.7%)相比，未使用佐剂的SCB1019(16.7%)的局部不良事件(AEs)发生率明显较低。SCB-1019的耐受性总体良好。SCB-1019的局部和全身不良事件(AEs)总体较轻，与生理盐水安慰剂组相当。未观察到与疫苗相关的严重不良事件(SAEs)，特殊关注的不良事件(AESIs)或局部不良事件(AEs)导致的停药。基于上述积极的Ⅰ期临床试验结果，公司计划将在2025年启动临床试验，用于评估SCB-1019 (未使用佐剂的二价RSV-A/B候选疫苗)在RSV疫苗重复接种以及呼吸道联合疫苗的应用情况。(jl/w)(港股报价延迟最少十五分钟。)AASTOCKS新闻","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1,"need_auth":false,"code":"91000000","status":"200"}}}

三叶草生物(02197.HK)二价RSV候选疫苗与GSKRSV疫苗头对头比较 在老年人受试者中获积极临床数据

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三叶草生物(02197.HK)二价RSV候选疫苗与GSKRSV疫苗头对头比较在老年人受试者中获积极临床数据