** Sino Biopharmaceutical 1177.HK rises 4.3% to HK$3.41; set for biggest one-day pct gain since Oct. 18

** Co buys 4.91% stake in LaNova Medicines for 142 mln yuan ($19.6 mln), enters into agreement for LM-108, a monoclonal antibody for various solid tumour treatment currently at Phase II clinical stage, in Mainland China region

** Says further cooperations with LaNova for various innovative bispecific antibody and antibody-drug conjugates in its pipelines

** Hong Kong's healthcare index .HSCIH up 2.9%

** Stock down 5.8% YTD

($1 = 7.2418 Chinese yuan renminbi)

(Reporting by Donny Kwok)

((donny.kwok@thomsonreuters.com))