BUZZ-Amylyx rises on late-stage trial update for low-blood sugar drug

Reuters
2024-12-04
BUZZ-Amylyx rises on late-stage trial update for low-blood sugar drug

** Shares of drug developer Amylyx Pharmaceuticals AMLX.O rise 1.9% to $5.45 premarket

** Co announces late-stage trial design for its experimental GLP-1 antagonist treatment, avexitide, to treat a type of low blood sugar called post-bariatric hypoglycemia $(PBH)$

** PBH is a condition that affects approximately 8% of people who have undergone bariatric surgery- AMLX

** The trial is designed to evaluate FDA-agreed upon primary goal of reduction in hypoglycemia or low blood sugar events- AMLX

** Co expects to dose the first study participant in the first quarter of 2025, followed by expected completion of recruitment in 2025, and anticipates topline data in 2026

** The late-stage trial will test the efficacy and safety of avexitide in participants with PBH following gastric bypass surgery

** Up to last close, stock was down 63.7% YTD

(Reporting by Sneha S K)

((Sneha.SK@thomsonreuters.com;))

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