Novo Nordisk Reports 22% Weight Loss in Early Subcutaneous Amycretin Trial

Reuters
01-24

COPENHAGEN, Jan 24 (Reuters) - Novo Nordisk on Friday announced early-stage trial results for its amycretin obesity drug for subcutaneous injection, saying people with obesity or overweight treated with the drug achieved a 22% weight loss after 36 weeks.

Shares jumped on the release and traded up 12% in premarket trading.

Amycretin targets the same gut hormone that Wegovy mimics, known as GLP-1, but also a pancreas hormone called amylin that affects hunger.

"The results seen in the trial support the weight lowering potential of this novel unimolecular GLP-1 and amylin receptor agonist, amycretin, that we have previously seen with the oral formulation," Novo Nordisk's head of development Martin Lange said in a statement.

Novo is also developing amycretin as a weight-loss pill, which helped obese participants lose 13.1% of their weight after 12 weeks of treatment in an early-stage study.

The company said in September it plans to decide on further studies for amycretin after data from the trial with the subcutaneous version.

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