Wall Street's main indexes traded off session lows on Friday as investors assessed comments from Fed Chair Jerome Powell amid economic uncertainty fanned by the Trump administration's tariff policies. .N

At 13:30 EST, the Dow Jones Industrial Average .DJI was up 0.05% at 42,598.93. The S&P 500 .SPX was down 0.07% at 5,734.14, and the Nasdaq Composite .IXIC was down 0.16% at 18,041.25.

The top three S&P 500 .PG.INX percentage gainers:

** Walgreens Boots Alliance Inc WBA.OQ, up 7.6%

** Moderna Inc MRNA.OQ, up 7.5%

** Campbell's Co CPB.OQ, up 7.1%

The top three S&P 500 .PL.INX percentage losers:

** Hewlett Packard Enterprise Co HPE.N, down 15.4%

** Costco Wholesale Corp COST.OQ, down 7.4%

** Cooper Companies Inc COO.OQ, down 6.9%

The top three NYSE .PG.N percentage gainers:

** Nine Energy Service Inc NINE.N, up 19.3%

** Ameresco Inc AMRC.N, up 17.8%

** Wolfspeed Inc WOLF.N, up 15.3%

The top three NYSE .PL.N percentage losers:

** BigBear.ai Holdings Inc BBAI.N, down 21.7%

** Genesco Inc GCO.N, down 19.0%

** Entravision Communications Corp EVC.N, down 18.3%

The top three Nasdaq .PG.O percentage gainers:

** Bit Origin Ltd BTOG.OQ, up 165.7%

** Sunation Energy Inc SUNE.OQ, up 116.3%

** Dogwood Therapeutics Inc DWTX.OQ, up 59.1%

The top three Nasdaq .PL.O percentage losers:

** Scienture Holdings Inc SCNX.OQ, down 32.8%

** Avalon Globocare Corp ALBT.OQ, down 32.7%

** Acurx Pharmaceuticals Inc ACXP.OQ, down 30.2%

** Alibaba Group Holding Ltd BABA.N:

BUZZ - Shares hit over 3-yr peak on release of AI reasoning model nL2N3PQ07M

** Walgreens Boots Alliance Inc WBA.O:

BUZZ - Climbs on Sycamore's take-private deal for $10 billion nL3N3PQ1HQ

** Newmont Corp NEM.N:

** Barrick Gold Corp GOLD.N:

** Gold Fields Ltd GFI.N:

** Harmony Gold Mining Co Ltd HMY.N:

BUZZ - Gold miners rise as bullion prices edge higher on weak dollar nL3N3PQ0T2

** Gap Inc GAP.N:

BUZZ - Jumps as Q4 results beat estimates on strong holiday demand nL3N3PQ0TO

** Hewlett Packard Enterprises Co HPE.N:

BUZZ - Slumps after dour Q2 forecasts nL3N3PQ0VF

** Broadcom Inc AVGO.O:

BUZZ - Climbs after upbeat quarterly revenue forecast nL3N3PQ0WW

** Wayfair Inc W.N:

BUZZ - Rises after Jefferies upgrades to 'buy', co announces job cuts nL3N3PQ1AUx

** Traeger Inc COOK.N:

BUZZ - Drops after soft outlook, CFO transition nL6N3PQ0HS

** Lands End Inc LE.O:

BUZZ - Explores strategic options, including sale; shares up nL3N3PQ14C

** Zscaler Inc :

BUZZ - Rises as BofA upgrades to 'buy' nL3N3PQ15V

** CorMedix Inc CRMD.O:

BUZZ - Gains after Leerink starts coverage with 'outperform' nL3N3PQ16B

** Algonquin Power & Utilities Corp AQN.N:

BUZZ - Falls on fourth-quarter profit miss nL3N3PQ1GO

** General Motors Co GM.N:

** Ford Motor Co F.N:

** Aptiv PLC APTV.N:BUZZ - TD Cowen starts coverage on some US auto makers, expects sales to recover nL3N3PQ16P

**BigBear.ai Holdings Inc BBAI.N:BUZZ - Tumbles after Q4 miss, downbeat forecast nL6N3PQ0JZ

** Neumora Therapeutics Inc NMRA.O:BUZZ - Falls as J&J's setback triggers concerns over depression drug nL3N3PQ17A

** Chevron Corp CVX.N:

** Exxon Mobil Corp XOM.N:

** Halliburton Co HAL.N:

** Transocean Ltd RIG.N: BUZZ - Energy firms rise after Russia's Novak hints at OPEC+ output reversal nL3N3PQ1E7

** Jazz Pharmaceuticals Inc JAZZ.O:BUZZ - Climbs after Morgan Stanley raises PT nL3N3PQ183

** KLX Energy Services Holdings Inc KLXE.O:BUZZ - Gains on debt refinancing plan nL3N3PQ1A9

** Cooper Companies Inc COO.O:BUZZ - Falls to 15-month low on Q1 revenue miss nL3N3PQ0Y9

** CH Robinson Worldwide Inc CHRW.O:

** Old Dominion Freight Line Inc ODFL.O:

** JB Hunt Transport Services Inc JBHT.O:BUZZ - Deutsche Bank initiates coverage on some US trucking firms nL3N3PQ1B6

** Samsara Inc IOT.N:BUZZ - Slides after Q4 beat, in line guidance

nL6N3PQ0LA

** Intuitive Machines Inc LUNR.O:BUZZ - Slides after second sideways moon landing nL3N3PQ1CO

** Air Lease Corp AL.N:BUZZ - Falls after brokerage downgrades to 'underperform' nL3N3PQ1E8

** New Fortress Energy Inc NFE.O:

** Energy Transfer LP ET.N:

** Williams Companies Inc WMB.N:

** United States Natural Gas Fund LP UNG.N:BUZZ - Natgas companies slip on milder weather forecasts, lower demand nL3N3PQ1EA

** Affinity Bancshares Inc AFBI.O: BUZZ - Rises on stock repurchase plan nL3N3PQ1F7

** Mobileye Global Inc MBLY.O:BUZZ - Rises after Steve Cohen's Point72 reports 5% stake nL6N3PQ0MP

** Potbelly Corp PBPB.O:BUZZ - Shares flop after Q4 results, guidance nL2N3PQ0UQ

** Visionary Holdings Inc GV.O:BUZZ - Surges on order for 12,000 EVs in Hong Kong nL3N3PQ1F2

** Biohaven Ltd BHVN.N:BUZZ - Drops as Morgan Stanley cuts PT after bipolar drug failure nL3N3PQ1DL

** MeridianLink Inc MLNK.N:BUZZ - Hits over one-month high after Q4 revenue beats expectations nL3N3PQ1IH

** Wolfspeed Inc WOLF.N:BUZZ - Jumps after lowering capital expenditures forecast, job cuts announcement nL3N3PQ1GV

** JPMorgan Chase & Co JPM.N:

** Morgan Stanley MS.N:

** $Bank of America Corp(BAC-N)$ BAC.N:

** Wells Fargo & Co WFC.N:BUZZ - Wall Street lenders dive after jobs data deepens economic slowdown worries nL3N3PQ1JC

** Velocity Financial Inc VEL.N:BUZZ - Hits all-time high after Q4 profit beat nL3N3PQ1J7

(Compiled by Rajarshi Roy and Anshuman Tripathy)

((Rajarshi.Roy@thomsonreuters.com))