** Shares of Alphamab Oncology 9966.HK jump as much as 15.8% to HK$6.07, set for biggest one-day pct gain since February 27

** Stock top pct gainer on healthcare index .HSCIH, which is up 1.1%

** The oncology drugs developer expects to record a net profit of 150 mln yuan ($20.6 mln) for 2024 as compared to a loss of 210.6 mln yuan in 2023; this is the first time the company expects to achieve an annual profit

** The Hang Seng Commerce & Industry Index .HSNC jumps 1.9%, Hang Seng Index .HSI rises 1.6%

** Stock up 73.4% YTD

($1 = 7.2658 Chinese yuan renminbi)

(Reporting by Donny Kwok)

((donny.kwok@thomsonreuters.com))