U.S. stocks traded mostly lower midway through trading, with the Dow Jones index falling by around 0.1% on Wednesday.

The Dow traded down 0.05% to 42,567.48 while the NASDAQ fell 1.58% to 17,982.46. The S&P 500 also fell, dropping, 0.81% to 5,729.89.

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Leading and Lagging SectorsEnergy shares jumped by 1.5% on Wednesday.

In trading on Wednesday, information technology shares fell by 1.5%.

Top Headline

Cintas Corporation (NASDAQ:CTAS) shares jumped over 8% on Wednesday after the company posted better-than-expected third-quarter earnings.

Cintas reported quarterly earnings of $1.13 per share which beat the analyst consensus estimate of $1.06 per share. The company reported quarterly sales of $2.609 billion which beat the analyst consensus estimate of $2.597 billion.

Equities Trading UP                       

• Worthington Enterprises, Inc. (NYSE:WOR) shares shot up 20% to $49.96 as the company posted better-than-expected earnings for the third quarter.
• Shares of OSR Holdings, Inc. (NASDAQ:OSRH)got a boost, surging 92% to $3.0805 after its subsidiary, Vaximm AG, announced Phase 2a trial results for VXM01 and Avelumab combination therapy in glioblastoma, demonstrating safety and tolerability.
• VivoPower International PLC (NASDAQ:VVPR) shares were also up, gaining 110% to $4.7601. The company is in advanced bilateral negotiations on all-cash takeover offer at enterprise value of $120 million.

Equities Trading DOWN

• Acrivon Therapeutics, Inc (NASDAQ:ACRV) shares dropped 37% to $3.38. HC Wainwright & Co. analyst Emily Bodnar maintained Acrivon Therapeutics with a Buy and lowered the price target from $22 to $19.
• Shares of Intchains Group Limited (NASDAQ:ICG) were down 27% to $3.00 after the company announced entry into agreement for registered direct offering of its ADSs and warrants.
• Aclarion, Inc. (NASDAQ:ACON) was down, falling 29% to $0.5326 after the company announced a 1-for-27 reverse stock split.

CommoditiesIn commodity news, oil traded up 1.4% to $69.96 while gold traded down 0.1% at $3,023.10.

Silver traded down 0.1% to $34.165 on Wednesday, while copper rose 1.2% to $5.2740.

Euro zone

European shares were mostly lower today. The eurozone's STOXX 600 dipping 0.48%, Germany's DAX 40 fell 0.77% and France's CAC 40 dipped 0.63%. Spain's IBEX 35 Index fell 0.17%, while London's FTSE 100 gained 0.35%.

Asia Pacific Markets

Asian markets closed mixed on Wednesday, with Japan's Nikkei 225 gaining 0.65%, China's Shanghai Composite Index falling 0.04%, Hong Kong's Hang Seng Index rising 0.60% and India's BSE Sensex falling 0.93%.

Economics

• U.S. new orders for manufactured durable goods rose 0.9% month-over-month to $289.3 billion in February.
• U.S. mortgage applications declined by 2% in the week ending March 21, compared to a 6.2% fall in the previous period.

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