Ascentage Pharma Says 2 Investigational Drugs Added to 2025 CSCO Guidelines

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Ascentage Pharma (AAPG) said Monday that two of its drug candidates, lisaftoclax and olverembatinib, were included in the 2025 Chinese Society of Clinical Oncology Guidelines.

The company said lisaftoclax is first recommended in the CSCO guidelines as a potential treatment for relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma.

The investigational drug is currently under priority review in China following a November 2024 new drug application, Ascentage said.

Olverembatinib received an upgraded recommendation for use in children with leukemia and retained several existing recommendations for adult leukemia treatment, according to the company.

Ascentage said the drug remains part of China's national reimbursement drug list and is co-marketed in the country with Innovent Biologics.

The investigational drugs have not been approved in the US, Ascentage added.

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