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Bicara Therapeutics
15.51
+1.69
12.23%
盘后:
15.51
0.0000
0.00%
17:52 EDT
成交量:
117.58万
成交额:
1,807.42万
市值:
8.46亿
市盈率:
-3.83
高:
16.22
开:
14.10
低:
13.66
收:
13.82
数据加载中...
总览
公司
新闻
公告
公司资料
公司名字:
Bicara Therapeutics
交易所:
NASDAQ
成立时间:
2018
员工人数:
55
公司地址:
116 Huntington Avenue,Suite 703,Boston,Massachusetts,United States
官网:
http://www.bicara.com
邮编:
02116
电话:
617 468 4219
传真:
- -
简介:
Bicara Therapeutics Inc.于2018年12月12日在特拉华州注册成立。他们是一家临床阶段的生物制药公司,致力于为实体瘤患者带来变革性的双功能疗法。他们的主要项目阿法是一种双功能抗体,它结合了两个临床验证的靶点,即表皮生长因子受体(EGFR)导向的单克隆抗体和结合人类转化生长因子β(TGF-b)的结构域。通过这种双靶向机制,阿法有可能通过同时阻断癌症细胞固有的EGFR存活和增殖,以及肿瘤微环境(TME)中的免疫抑制性TGF-b信号传导,发挥强大的抗肿瘤活性。Ficerafusp alfa通过与肿瘤细胞上的EGFR结合,将TGF-b抑制剂直接引入TME,他们认为这将导致持久的反应和总生存率或OS的增加,同时减少通常与全身TGF-b抑制相关的不良反应。
董事
名称
职位
Claire Mazumdar
Chief Executive Officer and Director
Michael Powell
Chairperson of the Board
Ryan Cohlhepp, Pharm.D
President, Chief Operating Officer and Director
Carolyn Ng
Director
Christopher Bowden
Director
Heath Lukatch
Director
Jake Simson
Director
Kate Haviland
Director
Kiran Mazumdar Shaw
Director
Nils Lonberg
Director
Scott Robertson
Director
Vijay Kuchroo, D.V.M
Director
股东
名称
职位
Claire Mazumdar
Chief Executive Officer and Director
Ryan Cohlhepp, Pharm.D
President, Chief Operating Officer and Director
Ivan Hyep
Chief Financial Officer
David Raben
Chief Medical Officer
Lara Meisner
Chief Legal Officer
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