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Bicara Therapeutics
15.51
+1.69
12.23%
盤後:
15.51
0.0000
0.00%
17:52 EDT
成交量:
117.58萬
成交額:
1,807.42萬
市值:
8.46億
市盈率:
-3.83
高:
16.22
開:
14.10
低:
13.66
收:
13.82
資料載入中...
總覽
公司
新聞
公告
公司資料
公司名字:
Bicara Therapeutics
交易所:
NASDAQ
成立時間:
2018
員工人數:
55
公司地址:
116 Huntington Avenue,Suite 703,Boston,Massachusetts,United States
官網:
http://www.bicara.com
郵編:
02116
電話:
617 468 4219
傳真:
- -
簡介:
Bicara Therapeutics Inc.於2018年12月12日在特拉華州註冊成立。他們是一家臨床階段的生物製藥公司,致力於為實體瘤患者帶來變革性的雙功能療法。他們的主要項目阿法是一種雙功能抗體,它結合了兩個臨床驗證的靶點,即表皮生長因子受體(EGFR)導向的單克隆抗體和結合人類轉化生長因子β(TGF-b)的結構域。通過這種雙靶向機制,阿法有可能通過同時阻斷癌症細胞固有的EGFR存活和增殖,以及腫瘤微環境(TME)中的免疫抑制性TGF-b信號傳導,發揮強大的抗腫瘤活性。Ficerafusp alfa通過與腫瘤細胞上的EGFR結合,將TGF-b抑製劑直接引入TME,他們認為這將導致持久的反應和總生存率或OS的增加,同時減少通常與全身TGF-b抑制相關的不良反應。
董事
名稱
職位
Claire Mazumdar
Chief Executive Officer and Director
Michael Powell
Chairperson of the Board
Ryan Cohlhepp, Pharm.D
President, Chief Operating Officer and Director
Carolyn Ng
Director
Christopher Bowden
Director
Heath Lukatch
Director
Jake Simson
Director
Kate Haviland
Director
Kiran Mazumdar Shaw
Director
Nils Lonberg
Director
Scott Robertson
Director
Vijay Kuchroo, D.V.M
Director
股東
名稱
職位
Claire Mazumdar
Chief Executive Officer and Director
Ryan Cohlhepp, Pharm.D
President, Chief Operating Officer and Director
Ivan Hyep
Chief Financial Officer
David Raben
Chief Medical Officer
Lara Meisner
Chief Legal Officer
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