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Camizestrant與芙仕得相比顯著延緩晚期ER陽性乳腺癌患者疾病進展，延長至少3.5個月患者獲益

KN046聯合白蛋白紫杉醇用於三陰乳腺癌治療的最終研究結果在SABCS 2022公佈

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12:57","pubTimestamp":1670821020,"startTime":"0","endTime":"0","summary":"Camizestrant在没有检测到ESR1突变的患者中也有疗效，75mg和150mg剂量水平下疾病进展或死亡风险分别降低22%和24%。Camizestrant的耐受性普遍良好，其安全性与以前的试验中观察到的一致，没有发现新的安全信号。阿斯利康为评估Camizestrant治疗晚期乳腺癌制定了广泛的临床开发计划。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://wwwold.prnasia.com/story/archive/3962076_ZH62076_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"prnasia","symbols":["BK4023","HR","LU0320765992.SGD","PFS","BK4195","CBR","BK4568","CDK","BK4203","AZN","LU0889565916.HKD","LU0109394709.USD","BK4007"],"gpt_icon":0},{"id":"2290748162","title":"KN046聯合白蛋白紫杉醇用於三陰乳腺癌治療的最終研究結果在SABCS 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10:30","pubTimestamp":1670812200,"startTime":"0","endTime":"0","summary":"KN046-203的初步研究结果已于2021年在AACR大会线上公开，本次公开的数据是该研究的最终研究结果。研究结果表明，KN046耐受性良好；KN046联合白蛋白结合型紫杉醇对晚期三阴乳腺癌患者有效，无论患者的PD-L1是否阳性，都显示出无进展生存期和总生存期获益。目前KN046四个注册临床试验正在进行中，其中KN046联合化疗一线治疗非小细胞肺癌的Ⅲ期临床研究中期分析成功达到预设PFS终点。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://wwwold.prnasia.com/story/archive/3962192_ZH62192_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"prnasia","symbols":["IE0004445015.USD","BK4512","BK4573","LU0198837287.USD","LU0234572021.USD","IE00B19Z9505.USD","BK4161","BK1574","BK4571","LU0109391861.USD","LU0417517546.SGD","BK4566","IE0009356076.USD","LU0456855351.SGD","BK4532","IE00BJJMRY28.SGD","LU0256863811.USD","09966","BK4576","LU0149725797.USD","BK4581","BK4574","LU0353189680.USD","BK4533","IE00B1XK9C88.USD","BK4170","IE00BJTD4V19.USD","LU0097036916.USD","ITT","LU0056508442.USD","LU0444971666.USD","IE00B3S45H60.SGD","BK4550","IE00BJJMRX11.SGD","BK4534","LU0109392836.USD","BK4575","LU0353189763.USD","IE00BSNM7G36.USD","LU0320765059.SGD","LU0289739343.SGD","IRC","IE00B1BXHZ80.USD","BK4553","CBR","BK4195","BK4515","LU0511384066.AUD","BK4527","IE0004445239.USD"],"gpt_icon":0}],"pageSize":20,"totalPage":1,"pageCount":1,"totalSize":2,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/CBR\",params:#limit:5,,,undefined,":[{"market":"US","date":"2016-11-08","symbol":"CBR","fiscalQuarterEnding":null,"expectedEps":-0.06,"name":null,"time":"盤前","type":"earning","dateTimestamp":1478581200000,"reportTimeType":"pre","actualEps":null},{"market":"US","date":"2016-08-04","symbol":"CBR","fiscalQuarterEnding":null,"expectedEps":-0.02,"name":null,"time":"盤前","type":"earning","dateTimestamp":1470283200000,"reportTimeType":"pre","actualEps":null},{"market":"US","date":"2016-05-05","symbol":"CBR","fiscalQuarterEnding":null,"expectedEps":-0.13,"name":null,"time":"盤前","type":"earning","dateTimestamp":1462420800000,"reportTimeType":"pre","actualEps":null},{"market":"US","date":"2016-02-18","symbol":"CBR","fiscalQuarterEnding":null,"expectedEps":0.04,"name":null,"time":"盤前","type":"earning","dateTimestamp":1455771600000,"reportTimeType":"pre","actualEps":0.01},{"market":"US","date":"2015-10-29","symbol":"CBR","fiscalQuarterEnding":null,"expectedEps":0.03,"name":null,"time":"盤前","type":"earning","dateTimestamp":1446091200000,"reportTimeType":"pre","actualEps":0.01}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"CBR\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"CBR\",market:\"US\",delay:false,,,undefined,":{}}}