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Wainwright initiates coverage on biopharma firm Actuate Therapeutics ACTU.O with \"buy\" rating ** Brokerage sets PT at $20, representing more than 100% upside to the stock's last close** In a mid-stage study, co's experimental therapy for a type of pancreatic cancer improved overall survival over chemotherapy alone, with a 37% reduction in the risk of death ** Brokerage says the trial data for the therapy, elraglusib, \"positions it as a frontrunner among competition\" for pancreatic cancer treatments ** Brokerage is optimistic about ACTU because the pancreatic cancer market has a significant unmet need ** Brokerage expects elraglusib to launch in 2029 and believes ACTU has a revenue potential of nearly $600 mln by 2033** ACTU has fallen 8.9% YTD  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250317:nL4N3Q00SZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BLTE","ACTU"],"gpt_icon":0},{"id":"2520549585","title":"Actuate Therapeutics Initiated at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2520549585","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520549585?lang=en_us&edition=fundamental","pubTime":"2025-03-17 19:03","pubTimestamp":1742209380,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ACTU/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 17, 2025 07:03 ET (11:03 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","ACTU","BK4139"],"gpt_icon":0},{"id":"2520517448","title":"Actuate Therapeutics, Inc. : H.c. 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Losartan in Patients With Previously Untreated Metastatic Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2514096218","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514096218?lang=en_us&edition=fundamental","pubTime":"2025-02-25 21:00","pubTimestamp":1740488400,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250225:nTUA2PHXYL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ACTU"],"gpt_icon":0},{"id":"2514670099","title":"Actuate Announces Completion of Enrollment in a Phase 2 Trial of Elraglusib in Combination with FOLFIRINOX and Losartan in Patients with Previously Untreated Metastatic Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2514670099","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514670099?lang=en_us&edition=fundamental","pubTime":"2025-02-25 21:00","pubTimestamp":1740488400,"startTime":"0","endTime":"0","summary":"Initial Data from this Phase 2 Trial Demonstrates Early Evidence of Clinical Activity of Elraglusib (9-ING-41) in Combination with FOLFIRINOX and Losartan in Untreated Metastatic Pancreatic Ductal Ade","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/25/3031941/0/en/Actuate-Announces-Completion-of-Enrollment-in-a-Phase-2-Trial-of-Elraglusib-in-Combination-with-FOLFIRINOX-and-Losartan-in-Patients-with-Previously-Untreated-Metastatic-Pancreatic-.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ACTU"],"gpt_icon":0},{"id":"2510327329","title":"Is Actuate Therapeutics (NASDAQ:ACTU) In A Good Position To Deliver On Growth Plans?","url":"https://stock-news.laohu8.com/highlight/detail?id=2510327329","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510327329?lang=en_us&edition=fundamental","pubTime":"2025-02-12 18:55","pubTimestamp":1739357746,"startTime":"0","endTime":"0","summary":"Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the right price. For example, biotech and mining exploration companies often lose money for years before finding success with a new treatment or mineral discovery. But while history lauds those rare successes, those that fail are often forgotten; who remembers Pets.com?Given this risk, we thought we'd take a look at whether Actuate Therapeutics  shareholders should be worried about its cash burn. In this article, we define cash burn as its annual  free cash flow, which is the amount of money a company spends each year to fund its growth. The first step is to compare its cash burn with its cash reserves, to give us its 'cash runway'.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/actuate-therapeutics-nasdaq-actu-good-105546392.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BGHQF748.EUR",".IXIC","QID","USAW.SI","NVIW.SI","BK4139","NQmain","IE00B3QW5Z07.USD","LU2095319765.USD","BK4588","PSQ","LU2210149790.SGD","LU2210150020.SGD","USJW.SI","BK4585","TQQQ","IE00BKPKM429.USD","TSYW.SI","IE00B64PRP62.GBP","ACTU","SQQQ","NDAQ","MNQmain","BK4112","QLD"],"gpt_icon":1},{"id":"2506626875","title":"Assault on retail penalty rates may spread to other jobs: ACTU","url":"https://stock-news.laohu8.com/highlight/detail?id=2506626875","media":"The Australian Financial Review","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506626875?lang=en_us&edition=fundamental","pubTime":"2025-01-28 14:52","pubTimestamp":1738047120,"startTime":"0","endTime":"0","summary":"The Australian Council of Trade Unions fears a push by major retailers to exempt senior staff from weekend rates and overtime could form a precedent for other industries, and has called for political parties to commit to protecting penalty rates.Coles, Woolworths, Kmart and Costco have united with other retail chains like 7-Eleven, T2 and Mecca to back an Australian Retailers Association application to the Fair Work Commission to relax rules on rostering, breaks and other minimum conditions in the retail industry award.Loading...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.afr.com/work-and-careers/workplace/assault-on-retail-penalty-rates-may-spread-to-other-jobs-actu-20250128-p5l7mz","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"afr_stock","symbols":["BK4550","LU1551013342.USD","BK4581","LU2125154935.USD","LU2360032135.SGD","BK4588","LU1035775433.USD","LU1116320737.USD","LU2360106947.USD","LU0689472784.USD","BK4533","LU0385154629.USD","LU0234570918.USD","LU0471298694.HKD","LU0820561909.HKD","LU1496350502.SGD","LU0265550946.USD","ACTU","LU2237438978.USD","LU0234572021.USD","XKO.AU","LU0471298777.SGD","IE0008368304.USD","XAO.AU","LU1323610961.USD","XJO.AU","LU1066053197.SGD","BK4504","LU0820561818.USD","LU2125154778.USD","LU2095319765.USD","LU1116320901.HKD","COST","BK4585","BK4596","LU0256863811.USD","LU0265550359.USD","LU1551013425.SGD","BK4139","IE00BKVL7J92.USD","BK4155","IE00B5TLWC47.USD","LU0079474960.USD","LU1066051498.USD","LU0417517546.SGD","LU1496350171.SGD","LU0943347566.SGD","LU2210149790.SGD","IE00BZ1G4Q59.USD","LU1069344957.HKD"],"gpt_icon":1},{"id":"2504824901","title":"ACTU: Aussies could be $165K worse off under a push to change superannuation guarantee","url":"https://stock-news.laohu8.com/highlight/detail?id=2504824901","media":"Sydney Morning Herald","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2504824901?lang=en_us&edition=fundamental","pubTime":"2025-01-17 12:29","pubTimestamp":1737088187,"startTime":"0","endTime":"0","summary":"Aussies could be $165,000 worse-off in retirement if a proposed change to superannuation guarantee is given the go ahead, the peak union body warns.","market":"us","thumbnail":"https://images.perthnow.com.au/publication/C-17419061/aaf4995610415e620b55b7c8a88e1c3d51bbe17e.jpg","type":0,"news_type":0,"thumbnails":["https://images.perthnow.com.au/publication/C-17419061/aaf4995610415e620b55b7c8a88e1c3d51bbe17e.jpg"],"rights":{"source":"perthnow_stock","url":"https://www.perthnow.com.au/business/actu-aussies-could-be-165k-worse-off-under-a-push-to-change-superannuation-guarantee-c-17419061","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.perthnow.com.au/business/actu-aussies-could-be-165k-worse-off-under-a-push-to-change-superannuation-guarantee-c-17419061","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"perthnow_stock","symbols":["XJO.AU","XKO.AU","ACTU","BK4139","XAO.AU"],"gpt_icon":0},{"id":"2501850577","title":"Actuate Therapeutics Gets Orphan Medicinal Product Label for Elraglusib in EU","url":"https://stock-news.laohu8.com/highlight/detail?id=2501850577","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501850577?lang=en_us&edition=fundamental","pubTime":"2025-01-07 23:34","pubTimestamp":1736264082,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics  said Tuesday that the European Medicines Agency has granted orphan medicinal product designation to elraglusib for the treatment of pancreatic ductal adenocarcinoma.The company said the designation is granted to therapies intended for the treatment of life-threatening diseases \"that affect no more than two in 10,000 people in the European Union and for which no satisfactory therapy is available.\"The label also provides certain benefits like reduced regulatory fees, and a potential 10-year market exclusivity, the firm said. It also has an orphan drug designation for Elraglusib in the US for the same indication.\"We look forward to reporting topline data from our Phase 2 trial in 1H 2025 and working closely with the EMA and the FDA to accelerate elraglusib's clinical development program in metastatic pancreatic cancer,\" said Chief Executive Officer Daniel Schmitt.Price: 7.85, Change: -0.43, Percent Change: -5.19","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","BK4139","BK4156","ACTU"],"gpt_icon":0},{"id":"2501910206","title":"BRIEF-Actuate Therapeutics Receives EMA Orphan Medicinal Product Designation For Elraglusib For The Treatment Of Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2501910206","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501910206?lang=en_us&edition=fundamental","pubTime":"2025-01-07 21:11","pubTimestamp":1736255505,"startTime":"0","endTime":"0","summary":"BRIEF-Actuate Therapeutics Receives EMA Orphan Medicinal Product Designation For Elraglusib For The Treatment Of Pancreatic CancerJan 7 (Reuters) - Actuate Therapeutics Inc ACTU.O:ACTUATE THERAPEUTICS","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250107:nTUA3HLZYK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ACTU"],"gpt_icon":0},{"id":"2501209815","title":"Actuate Therapeutics announces EMA granted OMPD to elraglusib","url":"https://stock-news.laohu8.com/highlight/detail?id=2501209815","media":"TIPRANKS","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501209815?lang=en_us&edition=fundamental","pubTime":"2025-01-07 21:11","pubTimestamp":1736255488,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics (ACTU) announced that the European Medicines Agency, EMA, has granted Orphan Medicinal Product Designation, OMPD, to elraglusi...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/actuate-therapeutics-announces-ema-granted-ompd-to-elraglusib?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/actuate-therapeutics-announces-ema-granted-ompd-to-elraglusib?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ACTU","LENZ","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":3,"pageCount":1,"totalSize":44}]}}