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While the fourth-quarter earnings season is nearing the end, other pipeline and regulatory updates were in focus.bluebird bio’s BLUE shares plunged after the company announced that it has entered into a definitive agreement to be acquired by funds managed by global investment firms Carlyle and SK Capital Partners, LP.Gilead Sciences, Inc. GILD announced that the European Medicines Agency  has validated the company’s marketing authorization application and EU-Medicines for all applications for its twice-yearly injectable HIV-1 capsid inhibitor, lenacapavir. Gilead is seeking approval for lenacapavir for the prevention of HIV as pre-exposure prophylaxis .Both these applications are being assessed under an accelerated assessment review timeline as the EMA’s Committee for Medicinal Products for Human Use  determined that twice-yearly lenacapavir for HIV prevention is a product of major interest for public health and therapeutic innovation.BioMarin","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biotech-stock-roundup-blue-down-141900146.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00B7SZLL34.SGD","LU0234570918.USD","IE00BZ1G4Q59.USD","BK4578","BLUE","BK4532","LU1839511570.USD","LU0289739699.SGD","LU2087621335.USD","GILD","LU1066053197.SGD","BK4588","BK4139","LU1066051498.USD","LU2089984988.USD","IE00B3T34201.USD","CHMP","BK4585","LU0889565916.HKD","BK4566","BK4556","IE00B19Z3B42.SGD","BK4568","TRDA","IE0002270589.USD","LU1571399168.USD","LU0058720904.USD","LU1430594728.SGD","BK4087","BK4583","IE00BKVL7J92.USD","BMRN","LU0320765992.SGD","BK4550","LU2468319806.SGD","LU1585245621.USD","IE00BSNM7G36.USD","IE00B19Z3581.USD","LU0109394709.USD"],"gpt_icon":0},{"id":"2513672328","title":"JPMorgan Upgrades bluebird bio to Neutral From Underweight","url":"https://stock-news.laohu8.com/highlight/detail?id=2513672328","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513672328?lang=en_us&edition=fundamental","pubTime":"2025-02-24 20:33","pubTimestamp":1740400380,"startTime":"0","endTime":"0","summary":"bluebird bio (BLUE) has an average rating of hold and mean price target of $14.50, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BLUE"],"gpt_icon":0},{"id":"2513728770","title":"bluebird bio Raised to Neutral From Underweight by JP Morgan","url":"https://stock-news.laohu8.com/highlight/detail?id=2513728770","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513728770?lang=en_us&edition=fundamental","pubTime":"2025-02-24 20:10","pubTimestamp":1740399000,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BLUE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 24, 2025 07:10 ET (12:10 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BLUE"],"gpt_icon":0},{"id":"2513744614","title":"BUZZ-J.P. 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Morgan upgrades gene therapy maker bluebird bio BLUE.O to \"neutral\" from \"underweight\" rating, citing co's announcement that it would be take","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250224:nL3N3PF0NA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BLUE"],"gpt_icon":0},{"id":"2513426937","title":"Calendar of U.S. Earnings Expected in the Week Ahead","url":"https://stock-news.laohu8.com/highlight/detail?id=2513426937","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513426937?lang=en_us&edition=fundamental","pubTime":"2025-02-24 19:00","pubTimestamp":1740394800,"startTime":"0","endTime":"0","summary":"Major companies tentatively scheduled to report quarterly earnings in the week ahead, with earnings estimates provided by FactSet Research Systems Inc.·Clean Energy Fuels                               4Q       .00    4:05 PM. ·Clear Channel Otdr                                4Q       .01    7:00 AM. ·DMC Global Inc.                                  4Q      (.27)   4:05 PM. ·Domino's Pizza Inc.                               4Q      4.90    6:05 AM","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AORT","DPZ","BLUE","FMS","CLNE","SIBN","AROC","CWEN.A","CGBD","CTRA","PRIM","NVTS","SAM","PLOW","GO","AMT","O","PSA","BMO","HLX","JBTM","MAX","HSTM","CNNE","HLIO","BSM","DRVN","MODG","FLYW","CAVA","NTST","DAWN","CPNG","VNOM","HVT.A","CCO","BRDG","CWEN","CLF","AS","CECO","KSPI","IMOS","UCTT","OMAB","OC","LTC","CWH","CIVI"],"gpt_icon":1},{"id":"2513583716","title":"U.S. RESEARCH ROUNDUP-Amneal pharma, Aramark, Bluebird Bio","url":"https://stock-news.laohu8.com/highlight/detail?id=2513583716","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513583716?lang=en_us&edition=fundamental","pubTime":"2025-02-24 15:19","pubTimestamp":1740381562,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-Amneal pharma, Aramark, Bluebird BioFeb 24 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Amneal ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250224:nL3N3PF0E7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ARMK","LU0054578231.USD","COTY","LU2361044949.HKD","DBX","PG","LU1066053197.SGD","CAKE","KNSL","COP","IE00B3PB1722.GBP","RIGL","AMRX","SGXZ99366536.SGD","BBWI","RNG","LU1814569148.SGD","EMR","FIVN","LU0648000940.SGD","KVUE","LU0056508442.USD","LU1868837136.USD","LU1914381329.SGD","IE00BGHQF524.EUR","LU0130517989.USD","LU1974910355.USD","LU0823421416.USD","IE00B19Z9505.USD","LU0079474960.USD","IE00BFXG1179.USD","LU1267930730.SGD","AKAM","CRL","LU2265009873.SGD","LU1691799644.USD","UTZ","AMH","BK4121","LOAR","LU1934455194.USD","LU2326559502.SGD","BK4528","V","IE00BVYPNW00.USD","IE00B3T34201.USD","LU0345781412.USD","IE00BQXX3F31.USD","BLUE"],"gpt_icon":1},{"id":"2513792033","title":"bluebird bio Inc : JP Morgan Raises to Neutral From Underweight","url":"https://stock-news.laohu8.com/highlight/detail?id=2513792033","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513792033?lang=en_us&edition=fundamental","pubTime":"2025-02-24 13:23","pubTimestamp":1740374629,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250224:nFWN3PF0A2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4556","BK4578","BK4139","BLUE"],"gpt_icon":0},{"id":"2513119162","title":"BofA moves to No Rating on Bluebird Bio after deal announcement","url":"https://stock-news.laohu8.com/highlight/detail?id=2513119162","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513119162?lang=en_us&edition=fundamental","pubTime":"2025-02-22 03:20","pubTimestamp":1740165610,"startTime":"0","endTime":"0","summary":"BofA moved to No Rating on Bluebird Bio (BLUE) after the company announced it has entered a definitive merger agreement under which Carlyle and SK ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/bofa-moves-to-no-rating-on-bluebird-bio-after-deal-announcement?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/bofa-moves-to-no-rating-on-bluebird-bio-after-deal-announcement?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BLUE","BK4578","BK4556"],"gpt_icon":0},{"id":"2513221677","title":"Top Midday Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2513221677","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513221677?lang=en_us&edition=fundamental","pubTime":"2025-02-22 02:50","pubTimestamp":1740163822,"startTime":"0","endTime":"0","summary":"Bluebird Bio  said Friday it agreed to be acquired by Carlyle Group  managed funds and SK Capital Partners.Under the terms of the deal, bluebird shareholders will receive $3.00 per share in cash and a contingent value of $6.84 per share, payable in cash if bluebird's current product portfolio earns $600 million in net sales in any trailing 12-month period before or ending on Dec. 31, 2027.Shares slumped 41% following a surge in intraday trading volume to over 4.5 million from a daily average of about 392,000.AXT  reported a wider Q4 non-GAAP loss late Thursday compared with a year ago and sequentially. Wedbush adjusted AXT's price target to $4.50 from $5.50 while maintaining its outperform rating.Shares of AXT sank 31%, with intraday trading volume catapulting to over 5.3 million versus a daily average of about 361,000.Akamai Technologies  has \"limited\" short-term growth opportunities, BofA Securities said in a note Friday, following the company's Q4 results overnight. BofA downgraded ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","IE00BGHQF748.EUR","BK4135","AKAM","BK4588","BK4578","BK4608","AXTI","BK4116","BK4554","IE00B3QW5Z07.USD","BK4585","LU2286300806.USD","IE00B64PRP62.GBP","BK4147","BLUE","CG","BK4556"],"gpt_icon":0},{"id":"2513321824","title":"Bluebird bio's CVR Payout Seen as a Stretch -- Market Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2513321824","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513321824?lang=en_us&edition=fundamental","pubTime":"2025-02-22 01:24","pubTimestamp":1740158640,"startTime":"0","endTime":"0","summary":"1224 ET - Bluebird bio's deal to be taken private will leave investors with a rich reward or a steep haircut, depending on sales of the company's gene therapies over the next three years. Analysts at William Blair think it will be the latter. Bluebird holders will get an initial $3 a share, 57% below Thursday's closing price, but contingent value rights that would be triggered by 12-month sales of $600 million would bring another $6.84 a share, for a 40% premium. William Blair says it currently models bluebird's sales reaching only $546.4 million in 2027, making the probability of achieving the CVR contingency low. Bluebird slide 39% to $4.29. 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Bio trading resumes","url":"https://stock-news.laohu8.com/highlight/detail?id=2513299576","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513299576?lang=en_us&edition=fundamental","pubTime":"2025-02-21 22:40","pubTimestamp":1740148857,"startTime":"0","endTime":"0","summary":"09:37 EST Bluebird Bio (BLUE) trading resumes Published first on TheFly – the ultimate source for real-time, market-moving breaking financial 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market-moving...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/bluebird-bio-trading-halted-volatility-trading-pause?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/bluebird-bio-trading-halted-volatility-trading-pause?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4556","BK4139","BLUE","BK4578"],"gpt_icon":0},{"id":"2513029577","title":"Bluebird Bio downgraded to Neutral from Outperform at 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