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Denali Therapeutics Inc.

19.69

-0.0100-0.05%

Post-market: 19.760.0700+0.36%19:34 EST

Volume:1.26M

Turnover:24.54M

Market Cap:3.12B

PE:-6.63

High:19.76

Open:19.46

Low:19.05

Close:19.70

52wk High:23.77

52wk Low:10.57

Shares:158.59M

Float Shares:144.00M

Volume Ratio:0.91

T/O Rate:0.88%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.9700

EPS(LYR):-2.9700

ROE:-45.69%

ROA:-27.56%

PB:3.08

PE(LYR):-6.63

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Overview Company News Filings

Denali Therapeutics reports $872.9 million cash position ahead of key 2026 milestones

Denali Therapeutics Inc - FDA Lifts Clinical Hold on Dnl952, Phase 1 Study to Proceed

THOMSON REUTERS

Denali Therapeutics Inc - Prepares for FDA Approval and Launch of Tividenofusp Alfa

THOMSON REUTERS

Denali Therapeutics Announces Key Anticipated Milestones and Priorities for 2026 Including Commercial Launch of Tividenofusp Alfa for Hunter Syndrome

Denali Therapeutics Reports Positive Phase 1/2 Results for Tividenofusp Alfa in Hunter Syndrome

Does Denali’s $200M Equity Raise And FDA Talks Change The Bull Case For DNLI?

Simply Wall St.

Does Denali Therapeutics' (DNLI) Discounted Equity Raise Reveal a New Phase in Its Risk Strategy?

Simply Wall St.

Denali Therapeutics Shares Fall in Premarket on Share Offering Price

BRIEF-Denali Therapeutics Says Co Prices Public Offering Of 9.14 Mln Shares At $17.50 Each

Denali Therapeutics Inc - Prices Public Offering of 9,142,857 Shares at $17.50 Each

THOMSON REUTERS

BUZZ-Denali Therapeutics slides after launching $200 million share sale

Denali Therapeutics: to Offer & Sell $200 Mln of Shares of Its Common Stock and, in Lieu of Common Stock to Certain Investors, Warrants

THOMSON REUTERS

Denali Therapeutics Inc - Grants Underwriters Option for $30 Mln Additional Shares

THOMSON REUTERS

Denali Therapeutics Announces Proposed Offering of Common Stock and Pre-Funded Warrants

Denali Flags Minimal Delay After FDA Halts Rare Disease Trial Start

Benzinga_recent_news

Denali Therapeutics, Royalty Pharma Enter $275 Million Royalty Funding Agreement for Hunter Syndrome Treatment

Denali Therapeutics Inc - Royalty Pharma to Receive 9.25% Royalty on Worldwide Sales of Tividenofusp Alfa From Denali

THOMSON REUTERS

Press Release: Denali Therapeutics and Royalty Pharma Announce $275 Million Royalty Funding Agreement

Denali Therapeutics Drops Amid Volume Surge, Last Down 6.3%

THOMSON REUTERS

Denali Therapeutics Q3 Operating Expenses USD 137.434 Million

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Therapeutics reports $872.9 million cash position ahead of key 2026 milestones","url":"https://stock-news.laohu8.com/highlight/detail?id=2601897193","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601897193?lang=en_us&edition=fundamental","pubTime":"2026-01-06 21:03","pubTimestamp":1767704617,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc. reported that as of September 30, 2025, it held approximately $872.9 million in cash, cash equivalents, and marketable securities. In December 2025, the company raised around $200 million through an equity financing and announced a royalty funding agreement with Royalty Pharma, which could provide proceeds of up to $275 million based on future net sales of tividenofusp alfa. These developments indicate a significant strengthening of Denali’s financial position as it prepares for key milestones in 2026, including the potential US accelerated approval and launch of tividenofusp alfa.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Denali Therapeutics Inc. published the original content used to generate this news b","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nNDLB0dpW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DNLI","BK4535","BK4007","BK4548","BK4139","RPRX"],"gpt_icon":0},{"id":"2601975468","title":"Denali Therapeutics Inc - FDA Lifts Clinical Hold on Dnl952, Phase 1 Study to Proceed","url":"https://stock-news.laohu8.com/highlight/detail?id=2601975468","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601975468?lang=en_us&edition=fundamental","pubTime":"2026-01-06 21:00","pubTimestamp":1767704406,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nTUA3KPMNL:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4548","BK4139","BK4535","DNLI"],"gpt_icon":0},{"id":"2601897577","title":"Denali Therapeutics Inc - Prepares for FDA Approval and Launch of Tividenofusp Alfa","url":"https://stock-news.laohu8.com/highlight/detail?id=2601897577","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601897577?lang=en_us&edition=fundamental","pubTime":"2026-01-06 21:00","pubTimestamp":1767704406,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nTUA3KPMNL:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["DNLI","BK4139","BK4535","BK4548"],"gpt_icon":0},{"id":"2601897745","title":"Denali Therapeutics Announces Key Anticipated Milestones and Priorities for 2026 Including Commercial Launch of Tividenofusp Alfa for Hunter Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2601897745","media":"GlobeNewswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601897745?lang=en_us&edition=fundamental","pubTime":"2026-01-06 21:00","pubTimestamp":1767704400,"startTime":"0","endTime":"0","summary":"Preparing for FDA approval and commercial launch of tividenofusp alfa, Denali’s TransportVehicle (TV)-enabled investigational therapy for Hunter syndromeExpecting multiple clinical data readouts from ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/01/06/3213572/0/en/Denali-Therapeutics-Announces-Key-Anticipated-Milestones-and-Priorities-for-2026-Including-Commercial-Launch-of-Tividenofusp-Alfa-for-Hunter-Syndrome.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DNLI","BK4535","IND","BK4539","BK4139","BK4007","ETV","BK4548","TV","LENZ","BK4100","CTA"],"gpt_icon":0},{"id":"2595973547","title":"Denali Therapeutics Reports Positive Phase 1/2 Results for Tividenofusp Alfa in Hunter Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2595973547","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2595973547?lang=en_us&edition=fundamental","pubTime":"2025-12-30 21:00","pubTimestamp":1767099624,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Denali Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on December 30, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251230:nNDL4HKsX4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210150020.SGD","BK4585","IE00B3QW5Z07.USD","LU2210149790.SGD","IE00BKPKM429.USD","NDAQ","SG9999014039.USD","BK4548","IE00B64PRP62.GBP","DNLI","BK4588","BK4535","BK4112","SG9999014005.SGD","SG9999014021.USD","LU0314104364.USD","LU2095319765.USD","BK4139","SG9999014013.SGD","IE00BGHQF748.EUR"],"gpt_icon":0},{"id":"2593490448","title":"Does Denali’s $200M Equity Raise And FDA Talks Change The Bull Case For DNLI?","url":"https://stock-news.laohu8.com/highlight/detail?id=2593490448","media":"Simply Wall St.","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2593490448?lang=en_us&edition=fundamental","pubTime":"2025-12-24 02:15","pubTimestamp":1766513743,"startTime":"0","endTime":"0","summary":"Earlier this year, Denali Therapeutics completed a US$200,000,000 secondary offering of common shares and pre-funded warrants while engaging with the FDA on a potential priority review voucher tied to its therapies.\nThis combination of fresh capital and active regulatory dialogue may enhance Denali’s ability to advance its neurodegenerative drug pipeline more efficiently.\nWith the company’s recent equity raise in hand, we’ll now examine how this funding cushions Denali Therapeutics’...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dnli/denali-therapeutics/news/does-denalis-200m-equity-raise-and-fda-talks-change-the-bull","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dnli/denali-therapeutics/news/does-denalis-200m-equity-raise-and-fda-talks-change-the-bull","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4588","EQR","BK4585","DNLI","BK4548","BK4139","BK4535","BK4215"],"gpt_icon":0},{"id":"2592939707","title":"Does Denali Therapeutics' (DNLI) Discounted Equity Raise Reveal a New Phase in Its Risk Strategy?","url":"https://stock-news.laohu8.com/highlight/detail?id=2592939707","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592939707?lang=en_us&edition=fundamental","pubTime":"2025-12-17 00:17","pubTimestamp":1765901823,"startTime":"0","endTime":"0","summary":"In December 2025, Denali Therapeutics completed a US$200,000,000 follow-on equity offering, issuing 9,142,857 common shares at US$17.50 and 2,285,714 pre-funded warrants at US$17.49, each at a US$0.875 discount per security.\nThe mix of common stock and pre-funded warrants highlights investor appetite for flexible exposure to Denali’s pipeline while expanding the company’s capital base.\nWe’ll now examine how this US$200,000,000 capital raise through discounted equity and pre-funded warrants...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dnli/denali-therapeutics/news/does-denali-therapeutics-dnli-discounted-equity-raise-reveal","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dnli/denali-therapeutics/news/does-denali-therapeutics-dnli-discounted-equity-raise-reveal","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["DNLI","BK4585","BK4535","BK4215","EQR","BK4139","BK4548","BK4588"],"gpt_icon":0},{"id":"2590058048","title":"Denali Therapeutics Shares Fall in Premarket on Share Offering Price","url":"https://stock-news.laohu8.com/highlight/detail?id=2590058048","media":"Dow Jones","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590058048?lang=en_us&edition=fundamental","pubTime":"2025-12-10 21:50","pubTimestamp":1765374600,"startTime":"0","endTime":"0","summary":"Denali Therapeutics shares were lower in premarket trading Wednesday after it priced its share offering below current trading levels.Shares were down 9.7% ahead of the morning bell at $17.75.The biotechnology company said it will offer 9.1 million shares at a price of $17.50 apiece.The stock has been under pressure in 2025, falling about 3.5% since the year began, and about 20% over the past 52 weeks.The company also issued prefunded warrants to purchase 2.3 million shares at a stock price of $17.49.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","DNLI","BK4007","BK4139","BK4548","BK4535","BK4539"],"gpt_icon":0},{"id":"2590088823","title":"BRIEF-Denali Therapeutics Says Co Prices Public Offering Of 9.14 Mln Shares At $17.50 Each","url":"https://stock-news.laohu8.com/highlight/detail?id=2590088823","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590088823?lang=en_us&edition=fundamental","pubTime":"2025-12-10 13:18","pubTimestamp":1765343921,"startTime":"0","endTime":"0","summary":"BRIEF-Denali Therapeutics Says Co Prices Public Offering Of 9.14 Mln Shares At $17.50 EachDec 10 (Reuters) - Denali Therapeutics Inc DNLI.O:DENALI THERAPEUTICS ANNOUNCES PRICING OF PUBLIC OFFERING OF ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251210:nTUA5J6P14:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4535","BK4139","DNLI","BK4548"],"gpt_icon":0},{"id":"2590770370","title":"Denali Therapeutics Inc - Prices Public Offering of 9,142,857 Shares at $17.50 Each","url":"https://stock-news.laohu8.com/highlight/detail?id=2590770370","media":"THOMSON REUTERS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590770370?lang=en_us&edition=fundamental","pubTime":"2025-12-10 13:14","pubTimestamp":1765343666,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251210:nTUA5J6P14:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4535","BK4548","DNLI"],"gpt_icon":0},{"id":"2590327584","title":"BUZZ-Denali Therapeutics slides after launching $200 million share sale","url":"https://stock-news.laohu8.com/highlight/detail?id=2590327584","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590327584?lang=en_us&edition=fundamental","pubTime":"2025-12-10 06:38","pubTimestamp":1765319930,"startTime":"0","endTime":"0","summary":"BUZZ-Denali Therapeutics slides after launching $200 million share sale** Drug developer Denali Therapeutics' DNLI.O shares slide 9% to $17.90 in extended trading** DNLI kicks off public offering of $200 million worth of shares and pre-funded warrants** Goldman Sachs, J.P. Morgan Securities, Morgan Stanley and Jefferies are joint book-running managers for offering** Proceeds will be used to advance commercial readiness and regulatory pathways for its drug pipeline, scale internal manufacturing capabilities, among other purposes** DNLI has 146.6 million outstanding shares as of September 30, according to prospectus** All 18 brokerages covering the stock rate it \"buy\" or higher; median PT $32 - data compiled by LSEG** As of last close, DNLI stock down 3.5% YTD  ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nL6N3XF0XI:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B19Z3581.USD","LU0061475181.USD","DNLI","BK4504","IE0004086264.USD","LU2237443622.USD","BK4548","LU0345770993.USD","LU1868836757.USD","LU1868837136.USD","LU1868837300.USD","LU2237443382.USD","IE0034235188.USD","IE0002270589.USD","LU2237438978.USD","LU2471134879.HKD","BK4588","LU2237443978.SGD","LU1894683348.USD","LU2750360997.AUD","BK4516","LU2237443465.HKD","LU0345770308.USD","BK4127","IE00B19Z3B42.SGD","LU0251131958.USD","LU2237443549.SGD","LU2237443895.HKD","BK4585","LU0742534661.SGD","LU1668664300.SGD","BK4552","LU2471134952.CNY","LU2265009873.SGD","LU2750360641.GBP","LU1804176565.USD","LU0251142724.SGD","BK4535","BK4550","LU0096364046.USD","LU0106831901.USD","IE00BSNM7G36.USD","LU1894683264.USD","LU1868836914.USD","BK4139","BK4533","LU2471134796.USD","LU1791807156.HKD","LU2471134523.USD","LU1868836591.USD"],"gpt_icon":0},{"id":"2590321079","title":"Denali Therapeutics: to Offer & Sell $200 Mln of Shares of Its Common Stock and, in Lieu of Common Stock to Certain Investors, Warrants","url":"https://stock-news.laohu8.com/highlight/detail?id=2590321079","media":"THOMSON REUTERS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590321079?lang=en_us&edition=fundamental","pubTime":"2025-12-10 05:01","pubTimestamp":1765314060,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nTUA3ZZKZR:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4535","BK4548","DNLI"],"gpt_icon":0},{"id":"2590032103","title":"Denali Therapeutics Inc - Grants Underwriters Option for $30 Mln Additional Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2590032103","media":"THOMSON REUTERS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590032103?lang=en_us&edition=fundamental","pubTime":"2025-12-10 05:01","pubTimestamp":1765314060,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nTUA3ZZKZR:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4535","BK4548","DNLI"],"gpt_icon":0},{"id":"2590324002","title":"Denali Therapeutics Announces Proposed Offering of Common Stock and Pre-Funded Warrants","url":"https://stock-news.laohu8.com/highlight/detail?id=2590324002","media":"GlobeNewswire","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590324002?lang=en_us&edition=fundamental","pubTime":"2025-12-10 05:01","pubTimestamp":1765314060,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif., Dec.  09, 2025  (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (NASDAQ: DNLI) today announced that it intends to offer and sell $200 million of shares of its common stock an","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/12/09/3202767/0/en/Denali-Therapeutics-Announces-Proposed-Offering-of-Common-Stock-and-Pre-Funded-Warrants.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1791710582.SGD","LU2347655156.SGD","BK4139","BK4539","LU0971096721.USD","LU1989772923.USD","IE00BKVL7J92.USD","IE00BZ1G4Q59.USD","LU0106831901.USD","LU0314104364.USD","LU0158827781.USD","LU1548497426.USD","LU0225283273.USD","LU0528227936.USD","LU0912757837.SGD","LU1244550577.SGD","LU1720051108.HKD","LU0557290698.USD","BK4588","LU0158827948.USD","LU0320765646.SGD","LU1732800096.USD","BK4504","LU1074936037.SGD","LU2089284900.SGD","BK4516","BK4007","LU1244550494.USD","BK4127","LU2089283258.USD","LU2271345857.HKD","LU2028103732.USD","LU0267386448.USD","LU1363072403.SGD","LU0795875086.SGD","LU1244550221.USD","LU1720051017.SGD","LU1732799900.SGD","LENZ","BK4535","BK4534","LU1668664300.SGD","LU0882574139.USD","DNLI","LU1791710400.SGD","LU2111349929.HKD","LU2023251221.USD","LU2133065610.SGD","LU0234570918.USD","LU0795875169.SGD"],"gpt_icon":0},{"id":"2589981924","title":"Denali Flags Minimal Delay After FDA Halts Rare Disease Trial Start","url":"https://stock-news.laohu8.com/highlight/detail?id=2589981924","media":"Benzinga_recent_news","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589981924?lang=en_us&edition=fundamental","pubTime":"2025-12-06 00:49","pubTimestamp":1764953340,"startTime":"0","endTime":"0","summary":"FDA placed hold on Denali's drug for Pompe disease, requesting changes to protocol. No additional studies requested. Minimal delays expected.","market":"sh","thumbnail":"https://cdn.benzinga.com/files/images/story/2025/12/05/FDA.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2025/12/05/FDA.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/news/fda/25/12/49235359/denali-flags-minimal-delay-after-fda-halts-rare-disease-trial-start","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/fda/25/12/49235359/denali-flags-minimal-delay-after-fda-halts-rare-disease-trial-start","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["BK4535","DNLI","BK4007","BK4548","IND","BK4139","RPRX"],"gpt_icon":0},{"id":"2588488474","title":"Denali Therapeutics, Royalty Pharma Enter $275 Million Royalty Funding Agreement for Hunter Syndrome Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2588488474","media":"Dow Jones","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588488474?lang=en_us&edition=fundamental","pubTime":"2025-12-04 21:06","pubTimestamp":1764853560,"startTime":"0","endTime":"0","summary":"Denali Therapeutics and Royalty Pharma entered a $275 million royalty funding agreement based on future sales of tividenofusp alfa.The companies said Thursday that the agreement is subject to various closing conditions. These include Denali receiving accelerated approval from the U.S. Food and Drug Administration for the treatment. A biologics license application for the accelerated approval of the treatment is currently under review by the FDA.Under the deal, Royalty Pharma would make an initial $200 million payment at the closing, as well as an additional $75 million payment if the treatment is approved by the European Medicines Agency by Dec. 31, 2029.In exchange, Royalty Pharma will receive a 9.25% royalty on worldwide net sales of tividenofusp alfa from Denali.The royalty payments would cease upon reaching a 3x multiple, or 2.5x multiple if achieved by the first quarter of 2039, the companies said.Royalty Pharma Chief Executive Pablo Legorreta said the company is \"thrilled to esta","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4535","BK4007","BK4139","DNLI","BK4548","RPRX","LENZ","BK4539"],"gpt_icon":0},{"id":"2588288964","title":"Denali Therapeutics Inc - Royalty Pharma to Receive 9.25% Royalty on Worldwide Sales of Tividenofusp Alfa From Denali","url":"https://stock-news.laohu8.com/highlight/detail?id=2588288964","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588288964?lang=en_us&edition=fundamental","pubTime":"2025-12-04 20:00","pubTimestamp":1764849601,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251204:nTUA30ZTCF:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4535","BK4007","BK4139","DNLI","BK4548","RPRX"],"gpt_icon":0},{"id":"2588889672","title":"Press Release: Denali Therapeutics and Royalty Pharma Announce $275 Million Royalty Funding Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2588889672","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588889672?lang=en_us&edition=fundamental","pubTime":"2025-12-04 20:00","pubTimestamp":1764849600,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif. and NEW YORK, Dec. 04, 2025  -- Denali Therapeutics Inc.  and Royalty Pharma plc  today announced a $275 million synthetic royalty funding agreement based on future net sales of tividenofusp alfa.\"We are delighted to partner with Denali and acquire a royalty on tividenofusp alfa, an innovative therapy that addresses a significant unmet need in the cognitive and physical manifestations of Hunter syndrome,\" said Pablo Legorreta, Chief Executive Officer and Chairman of the Board of Royalty Pharma. \"Denali's technology platform delivers therapeutics across the blood-brain barrier and is a promising new approach to brain diseases. We are thrilled to establish a relationship with Denali and believe tividenofusp alfa is a potential practice-changing therapy that could transform the lives of patients with Hunter syndrome.\"","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4604","DNLI","EMA","BK4555","LENZ","TM","03160","BK4081","BK4139","BK4585","BK4588","BK4548","BK4535","BK4099","BK4539","BK4007"],"gpt_icon":0},{"id":"2588770547","title":"Denali Therapeutics Drops Amid Volume Surge, Last Down 6.3%","url":"https://stock-news.laohu8.com/highlight/detail?id=2588770547","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588770547?lang=en_us&edition=fundamental","pubTime":"2025-12-02 03:19","pubTimestamp":1764616788,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251201:nL6N3X70YF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4535","DNLI","BK4548"],"gpt_icon":0},{"id":"2584669929","title":"Denali Therapeutics Q3 Operating Expenses USD 137.434 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2584669929","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584669929?lang=en_us&edition=fundamental","pubTime":"2025-11-20 00:58","pubTimestamp":1763571483,"startTime":"0","endTime":"0","summary":"Nov 06 (Reuters) - Denali Therapeutics Q3 operating income USD -137.434 million.:  ((Reuters Investor Briefs; email: reutersinvestor.briefs@thomsonreuters.com))  Source Date/Time = 06-NOV-202521:01:49.883 GMT","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251119:nRSD1LcbYQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4548","BK4535","DNLI"],"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":2,"totalSize":61,"code":"91000000","status":"200"}]}}