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ESSA Pharma

1.79

+0.02001.13%

Post-market: 1.790.00000.00%16:49 EDT

Volume:177.60K

Turnover:314.99K

Market Cap:79.46M

PE:-2.55

High:1.81

Open:1.77

Low:1.73

Close:1.77

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Overview Company News Filings

Essa Pharma downgraded to Neutral from Overweight at Piper Sandler

ESSA Pharma Inc : Piper Sandler Cuts to Neutral From Overweight; Cuts Target Price to $2 From $15

THOMSON REUTERS

ESSA Pharma Inc : Jefferies Cuts to Hold From Buy

THOMSON REUTERS

ESSA Pharma Faces Uncertainty After Discontinuing Masofaniten Programs, Receives Hold Rating

Essa Pharma downgraded to Hold from Buy at Jefferies

Top Midday Decliners

MT Newswires Live

Nasdaq Surges Over 200 Points; Amazon Shares Jump After Strong Results

Essa Pharma Cut to Hold From Buy by Jones Trading

ESSA Pharma tanks after terminating trial for its prostate cancer treatment

JonesTrading downgrades ESSA Pharma (EPIX) to a Hold

Top Premarket Decliners

MT Newswires Live

US Futures Rise Pre-Bell as Investors Await Key Employment, Manufacturing Data

MT Newswires Live

Essa Pharma Shares Drop After Lead Drug Candidate Fails

ESSA Pharma Shares Decline Premarket Amid Termination of Phase 2 Trial on Masofaniten, Enzalutamide Combination

MT Newswires Live

ESSA Pharma Announces Termination of Phase 2 Study Evaluating Masofaniten Combined With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer

THOMSON REUTERS

ESSA Pharma Announces Termination of Phase 2 Study Evaluating Masofaniten Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer

ESSA Pharma Insiders Placed Bullish Bets Worth US$709.0k

Simply Wall St.

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The trial tested masofaniten with enzalutamide versus enzalutamide alone in patients with metastatic castration-resistant prostate cancer who had not yet used second-generation antiandrogens. The decision followed an interim review of safety, PK, and efficacy data. Results showed a higher PSA90 response rate in patients treated with enzalutamide alone than expected based on historical data.Additionally, no clear benefit was seen with the masofaniten-enzalutamide combination over enzalutamide alone. A futility analysis showed a low likelihood of achieving the study’s primary endpoint. The combination was well-tolerated, with no new safety issues, matching the safety profile from Phase 1 studies. ESSA also said it will end other clinical studies on masofaniten, both as a monotherapy and in combination with other treatments, to focus resources.","market":"sg","thumbnail":"https://static.seekingalpha.com/cdn/s3/uploads/getty_images/1408664283/image_1408664283.jpg?io=getty-c-w750","type":0,"news_type":0,"thumbnails":["https://static.seekingalpha.com/cdn/s3/uploads/getty_images/1408664283/image_1408664283.jpg?io=getty-c-w750"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://seekingalpha.com/news/4233467-essa-pharma-tanks-after-terminating-trial-for-its-prostate-cancer-treatment","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"seekingalpha_trending_news","symbols":["BK4195","EPIX","BK4211","BK4139","ESSA"],"gpt_icon":0},{"id":"2480000980","title":"JonesTrading downgrades ESSA Pharma (EPIX) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2480000980","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480000980?lang=en_us&edition=fundamental","pubTime":"2024-11-01 20:27","pubTimestamp":1730464059,"startTime":"0","endTime":"0","summary":"ESSA Pharma (EPIX – Research Report) received a Hold rating and price target from JonesTrading analyst Soumit Roy today. The company’s shares close...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/jonestrading-downgrades-essa-pharma-epix-to-a-hold?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/jonestrading-downgrades-essa-pharma-epix-to-a-hold?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["EPIX","ESSA"],"gpt_icon":0},{"id":"2480073580","title":"Top Premarket Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2480073580","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480073580?lang=en_us&edition=fundamental","pubTime":"2024-11-01 20:15","pubTimestamp":1730463342,"startTime":"0","endTime":"0","summary":"ESSA Pharma (EPIX) shares plunged 70% in recent Friday premarket activity, a day after saying it planned to terminate a phase 2 clinical study evaluating the combination of masofaniten and enzalutamid","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4135","BK4132","DBRG","BK4233","EPIX","BK4160","BK4205","BK4139","TDS","LXRX"],"gpt_icon":0},{"id":"2480022190","title":"US Futures Rise Pre-Bell as Investors Await Key Employment, Manufacturing Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2480022190","media":"MT Newswires Live","labels":["economic"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480022190?lang=en_us&edition=fundamental","pubTime":"2024-11-01 20:11","pubTimestamp":1730463096,"startTime":"0","endTime":"0","summary":"US stock futures are moving higher in Friday's premarket activity as investors await key employment and manufacturing data set to be released later in the morning.The Dow Jones Industrial Average futu","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"economic","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":[".DJI","DOG","BK4516","IE00B4YYXB79.USD","MNQmain","BK4581","LU1023059063.AUD","GSAT","LU0058720904.USD","AAPL","QID","LU1093756325.SGD","SDOW","UDOW","SQQQ","BK4089","TOVX","ADN","LU0122379950.USD","LU1585245621.USD","IE00B4R5TH58.HKD","ADN.AU","BK4566","LXRX","DXD","QLD","DJX","IE000KEQY171.SGD","IE00BJJMRY28.SGD","LU1116320901.HKD","BK4533","VSME","IE0004445239.USD","IE00B19Z8W00.USD","BK4077","EPIX","PSQ",".SPX","HK0000320264.USD","MRK","NQmain","ISBC","LU1066051498.USD","DDM","TQQQ","LU0289739699.SGD","BK4573","LU1066051811.HKD",".IXIC"],"gpt_icon":1},{"id":"2480003074","title":"Essa Pharma Shares Drop After Lead Drug Candidate Fails","url":"https://stock-news.laohu8.com/highlight/detail?id=2480003074","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480003074?lang=en_us&edition=fundamental","pubTime":"2024-11-01 18:50","pubTimestamp":1730458200,"startTime":"0","endTime":"0","summary":"Essa Pharma's stock price plunged after the clinical-stage pharmaceutical company said it was throwing in the towel on its lead product candidate and exploring strategic alternatives.Shares of the South San Francisco, Calif., company were down 63.5% at $1.90 in premarket trading Friday.Essa late Thursday said it was ending Phase 2 study of masofaniten in prostate cancer after determining the study was unlikely to meet its primary endpoint.The company said it would also terminate other studies involving masofaniten and launch a process to review strategic options focused on maximizing shareholder value.Essa, which had a market capitalization of nearly $231 million based on Thursday's closing price of $5.20, said it had net working capital of $124.3 million as of Sept. 30.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","EPIX"],"gpt_icon":0},{"id":"2480074889","title":"ESSA Pharma Shares Decline Premarket Amid Termination of Phase 2 Trial on Masofaniten, Enzalutamide Combination","url":"https://stock-news.laohu8.com/highlight/detail?id=2480074889","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480074889?lang=en_us&edition=fundamental","pubTime":"2024-11-01 17:17","pubTimestamp":1730452643,"startTime":"0","endTime":"0","summary":"ESSA Pharma  shares were down more than 65% premarket Friday after the company said it decided to terminate the phase 2 trial evaluating the combination of masofaniten and enzalutamide in patients with metastatic castration-resistant prostate cancer compared with enzalutamide alone.The company said in a Thursday statement that the trial is unlikely to achieve the primary endpoint as interim data showed that \"there was no clear efficacy benefit seen with the combination of masofaniten plus enzalutamide compared to enzalutamide single agent.\"The study's primary endpoint is the proportion of patients reaching a PSA90 response and ESSA Pharma said trial data showed a \"much higher\" rate of PSA90 response in patients treated with enzalutamide monotherapy.Price: 1.81, Change: -3.39, Percent Change: -65.19","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ESSA","BK4195","EPIX","BK4211","BK4139"],"gpt_icon":0},{"id":"2480401370","title":"ESSA Pharma Announces Termination of Phase 2 Study Evaluating Masofaniten Combined With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2480401370","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480401370?lang=en_us&edition=fundamental","pubTime":"2024-11-01 08:57","pubTimestamp":1730422669,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241101:nTUA9BSTYZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["EPIX","BK4139"],"gpt_icon":0},{"id":"2480992015","title":"ESSA Pharma Announces Termination of Phase 2 Study Evaluating Masofaniten Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2480992015","media":"CNW Group","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480992015?lang=en_us&edition=fundamental","pubTime":"2024-11-01 08:57","pubTimestamp":1730422620,"startTime":"0","endTime":"0","summary":"Efficacy signals observed will not achieve ESSA's target product profile in patients with metastatic castration-resistant prostate cancer nave to second-generation antiandrogens. A futility analysis conducted as part of a protocol-specified interim review of the safety, PK and efficacy data showed the single-agent enzalutamide control arm performing better than historical controls and similar to the combination of masofaniten and enzalutamide and therefore, unlikely to achieve the primary endpoint of the study. \"Providing a meaningful clinical benefit to patients in our clinical trials, along with a robust safety profile, is of utmost importance to us at ESSA,\" said David Parkinson, MD, President and CEO. \"We designed this randomized study to rigorously evaluate the clinical benefit of adding masofaniten to enzalutamide. We made the difficult decision to terminate this Phase 2 study following the interim analysis because we concluded that the emerging efficacy profile of masofaniten co","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/NCoeSBo6eppkdUG_RCy_1Q--~B/aD0xNjt3PTE2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/cnwgroup.com/52fb2d19c4d2e9b4087db69dd3865cde","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/NCoeSBo6eppkdUG_RCy_1Q--~B/aD0xNjt3PTE2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/cnwgroup.com/52fb2d19c4d2e9b4087db69dd3865cde"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/essa-pharma-announces-termination-phase-005700928.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4211","EPIX","BK4139","ESSA","BK4195"],"gpt_icon":1},{"id":"2478021531","title":"ESSA Pharma Insiders Placed Bullish Bets Worth US$709.0k","url":"https://stock-news.laohu8.com/highlight/detail?id=2478021531","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2478021531?lang=en_us&edition=fundamental","pubTime":"2024-10-28 20:01","pubTimestamp":1730116862,"startTime":"0","endTime":"0","summary":"When a single insider purchases stock, it is typically not a major deal. However, when multiple insiders purchase stock, like in ESSA Pharma Inc.'s  instance, it's good news for shareholders.Although we don't think shareholders should simply follow insider transactions, we would consider it foolish to ignore insider transactions altogether.While ESSA Pharma insiders bought shares during the last year, they didn't sell. The average buy price was around US$5.35. Although they bought at below the recent share price, it is good to see that insiders are willing to invest in the company. You can see a visual depiction of insider transactions  over the last 12 months, below. By clicking on the graph below, you can see the precise details of each insider transaction!There are plenty of other companies that have insiders buying up shares. You probably do not want to miss this free list of undervalued small cap companies that insiders are 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