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KIO-104 is a novel, non-steroidal anti-inflammatory, small molecule inhibitor of dihydroorotate dehydrogenase . A Phase 2 clinical trial of KIO-104 for the treatment of retinal inflammation is expected to begin in the first half of 2025. This new patent is expected to extend protection of KIO-104 into 2043.This newly issued patent, titled, Polymorphs of a Dihydroorotate Dehydrogenase  Inhibitor, provides important and expanded intellectual property protection for KIO-104, specifically covering a critical and unique polymorph. This distinct crystalline form covered by the patent offers enhanced molecular stability and solubility, which are critical to optimize the manufacturing of the drug substance.\"Securing this patent issuance further extends and strengthens our existing IP","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/kiora-pharmaceuticals-secures-u-composition-120000613.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/kiora-pharmaceuticals-secures-u-composition-120000613.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["KPRX","KIO","BK4007"],"gpt_icon":0},{"id":"2510800551","title":"Kiora Receives Approval to Initiate KLARITY, a Phase 2 Clinical Trial of KIO-104 for the Treatment of Retinal Macular Edema","url":"https://stock-news.laohu8.com/highlight/detail?id=2510800551","media":"Newsfile","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510800551?lang=en_us&edition=fundamental","pubTime":"2025-02-11 19:45","pubTimestamp":1739274300,"startTime":"0","endTime":"0","summary":"KLARITY is a multi-center, open label study in up to 28 patients. The primary objective is to evaluate safety and tolerability of repeated doses of KIO-104 administered by standard intravitreal injection. Secondary endpoints will evaluate the magnitude of macula edema reduction, improvement in visual acuity and the systemic pharmacokinetic profile of KIO-104. The study will enroll patients with macular edema secondary to one of the following diseases: diabetic retinopathy, non-infectious uveitis, retinal vein occlusion, or post pseudophakic cataract surgery. The study will be performed in two parts as follows:. Part A  will assess the safety and efficacy of three injections administered once every two weeks in 8 subjects. Cohort 1 of will receive 3.5 μg doses of KIO-104 while Cohort 2 will receive 10 μg doses of KIO-104.KIO-104 works by suppressing T cell numbers and function in the eye responsible for driving inflammation. Specifically, KIO-104 inhibits the mitochondrial enzyme, DHODH","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/kiora-receives-approval-initiate-klarity-114500418.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/kiora-receives-approval-initiate-klarity-114500418.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["KIO","BK4007","KPRX"],"gpt_icon":0},{"id":"2483329918","title":"We Think Kiora Pharmaceuticals' (NASDAQ:KPRX) Healthy Earnings Might Be Conservative","url":"https://stock-news.laohu8.com/highlight/detail?id=2483329918","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483329918?lang=en_us&edition=fundamental","pubTime":"2024-11-15 19:06","pubTimestamp":1731668782,"startTime":"0","endTime":"0","summary":"Investors signalled that they were pleased with Kiora Pharmaceuticals, Inc.'s  most recent earnings report. This reaction by the market reaction is understandable when looking at headline profits and we have found some further encouraging factors.NasdaqCM:KPRX Earnings and Revenue History November 15th 2024. As finance nerds would already know, the accrual ratio from cashflow is a key measure for assessing how well a company's free cash flow  matches its profit. The accrual ratio subtracts the FCF from the profit for a given period, and divides the result by the average operating assets of the company over that time. This ratio tells us how much of a company's profit is not backed by free cashflow.How Is Dilution Impacting Kiora Pharmaceuticals' Earnings Per Share ?Three years ago, Kiora Pharmaceuticals lost money. Zooming in to the last year, we still can't talk about growth rates coherently, since it made a loss last year. What we do know is that while it's great to see a profit over","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/TLyt5D16lsSwRjJRVjlUTA--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/fd5474a7eee0c5f442903b68fe63249b","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/TLyt5D16lsSwRjJRVjlUTA--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/fd5474a7eee0c5f442903b68fe63249b"],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/think-kiora-pharmaceuticals-nasdaq-kprx-110622540.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":[".IXIC","NDAQ","KPRX"],"gpt_icon":0},{"id":"2483788032","title":"Kiora Pharmaceuticals: Strategic Advancements and Financial Stability Justify Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2483788032","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483788032?lang=en_us&edition=fundamental","pubTime":"2024-11-13 02:05","pubTimestamp":1731434726,"startTime":"0","endTime":"0","summary":"Maxim Group analyst Michael Okunewitch has maintained their bullish stance on KPRX stock, giving a Buy rating yesterday. Michael Okunewitch has giv...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/kiora-pharmaceuticals-strategic-advancements-and-financial-stability-justify-buy-rating?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/kiora-pharmaceuticals-strategic-advancements-and-financial-stability-justify-buy-rating?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["KPRX"],"gpt_icon":0},{"id":"2482776405","title":"Kiora Pharmaceuticals Price Target Maintained With a $10.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2482776405","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2482776405?lang=en_us&edition=fundamental","pubTime":"2024-11-12 18:16","pubTimestamp":1731406560,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/KPRX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 12, 2024 05:16 ET (10:16 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPRX"],"gpt_icon":0},{"id":"2482758786","title":"Kiora Pharmaceuticals’ Promising Growth Prospects: Buy Rating Backed by Clinical Advancements and Strong Financial Position","url":"https://stock-news.laohu8.com/highlight/detail?id=2482758786","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2482758786?lang=en_us&edition=fundamental","pubTime":"2024-11-12 01:25","pubTimestamp":1731345911,"startTime":"0","endTime":"0","summary":"Analyst Yi Chen of H.C. Wainwright reiterated a Buy rating on Kiora Pharmaceuticals (KPRX – Research Report), retaining the price target of $10.00....","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/kiora-pharmaceuticals-promising-growth-prospects-buy-rating-backed-by-clinical-advancements-and-strong-financial-position?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/kiora-pharmaceuticals-promising-growth-prospects-buy-rating-backed-by-clinical-advancements-and-strong-financial-position?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["KPRX"],"gpt_icon":0},{"id":"2482455453","title":"Kiora Pharmaceuticals Inc reports results for the quarter ended September 30 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2482455453","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2482455453?lang=en_us&edition=fundamental","pubTime":"2024-11-09 04:59","pubTimestamp":1731099549,"startTime":"0","endTime":"0","summary":"* Kiora Pharmaceuticals Inc    reported a quarterly adjusted loss of 81 cents per share for the quarter ended September 30, higher than the same quarter last year, when the company reported EPS of $-8","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Kiora Pharmaceuticals Inc reports results for the quarter ended September 30 - 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