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Milestone Pharmaceuticals Inc.

1.01

+0.121113.62%

Volume:2.62M

Turnover:2.52M

Market Cap:53.89M

PE:-1.51

High:1.03

Open:0.8891

Low:0.8800

Close:0.8889

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Overview Company News Filings

TD downgrades Milestone Pharmaceuticals, suspends target on Etripamil uncertainty

Milestone Pharmaceuticals Is Maintained at Buy by HC Wainwright & Co.

Milestone Pharmaceuticals Inc : H.c. Wainwright Cuts Target Price to $10 From $25

THOMSON REUTERS

BUZZ-Milestone Pharma falls after TD Cowen downgrades to "hold", removes PT

HC Wainwright Adjusts Price Target on Milestone Pharmaceuticals to $10 From $25, Maintains Buy Rating

MT Newswires Live

Milestone Pharmaceuticals Inc : TD Cowen Cuts to Hold From Buy

THOMSON REUTERS

TD Cowen Downgrades Milestone Pharmaceuticals to Hold From Buy

MT Newswires Live

BUZZ-U.S. STOCKS ON THE MOVE-GameStop, Oxford Industries, Wolfspeed

Milestone Pharmaceuticals Price Target Maintained With a $25.00/Share by HC Wainwright & Co.

Dow Tumbles Over 500 Points; Abacus Global Management Shares Spike Higher

Piper Sandler Adjusts Price Target on Milestone Pharmaceuticals to $4 From $5, Maintains Overweight Rating

MT Newswires Live

Milestone Pharmaceuticals Shares Down 64.7% After FDA Declines to Approve Co's Heart Rhythm Nasal Spray

THOMSON REUTERS

BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVT

BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray

Milestone Pharmaceuticals Shares Down 60% Premarket After FDA Declines to Approve Co's Heart Rhythm Nasal Spray

THOMSON REUTERS

FDA Rejects Milestone Pharmaceuticals' Etripamil Nasal Spray

US FDA declines to approve Milestone Pharma's heart rhythm nasal spray

Milestone Pharmaceuticals Inc - Inspection Required at Facility Performing Etripamil Release Testing

THOMSON REUTERS

Milestone Pharmaceuticals Inc - FDA Raises No Concerns on Etripamil Clinical Safety or Efficacy

THOMSON REUTERS

Milestone Pharmaceuticals Inc - Company to Submit Additional Info on Nitrosamine Impurities

THOMSON REUTERS

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While no safety or efficacy concerns were raised, the agency requested additional data on nitrosamine impurities based on new draft guidance published in September 2024, months after MIST had resubmitted its New Drug Application . The FDA also flagged the need for an inspection at a third-party facility performing release testing, which changed ownership during the New Drug Application review.TD expressed concerns over etripamil’s commercial viability, noting Milestone Pharmaceuticals' limited capital reserves. The company had ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/td-downgrades-milestone-pharmaceuticals-suspends-194848951.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TD","MIST"],"gpt_icon":0},{"id":"2524949144","title":"Milestone Pharmaceuticals Is Maintained at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2524949144","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524949144?lang=en_us&edition=fundamental","pubTime":"2025-04-02 00:43","pubTimestamp":1743525780,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/MIST/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 01, 2025 12:43 ET (16:43 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIST"],"gpt_icon":0},{"id":"2524146506","title":"Milestone Pharmaceuticals Inc : H.c. Wainwright Cuts Target Price to $10 From $25","url":"https://stock-news.laohu8.com/highlight/detail?id=2524146506","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524146506?lang=en_us&edition=fundamental","pubTime":"2025-04-01 23:33","pubTimestamp":1743521611,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250401:nFWN3QF16X:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2524781143","title":"BUZZ-Milestone Pharma falls after TD Cowen downgrades to \"hold\", removes PT","url":"https://stock-news.laohu8.com/highlight/detail?id=2524781143","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524781143?lang=en_us&edition=fundamental","pubTime":"2025-04-01 23:06","pubTimestamp":1743520012,"startTime":"0","endTime":"0","summary":"BUZZ-Milestone Pharma falls after TD Cowen downgrades to \"hold\", removes PT** Shares of drug developer Milestone Pharmaceuticals MIST.O fall 8% to 73 cents, extending decline to third day. ** Brokerage TD Cowen downgrades MIST to \"hold\" from \"buy\", removes PT. ** Cites etripamil's regulatory and commercial timing uncertainty. ** \"The lack of clarity on regulatory timelines puts additional strain on the company's limited capital,\" says brokerage. ** MIST shares fell ~61% on Friday after the U.S. FDA declined to approve its nasal spray, Cardamyst, to treat a type of heart condition. ** Including session moves, MIST stock down ~69% YTD compared to ~5% decline in the S&P 500 index 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20:41","pubTimestamp":1743511274,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250401:nFWN3QF15O:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2524186197","title":"TD Cowen Downgrades Milestone Pharmaceuticals to Hold From Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2524186197","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524186197?lang=en_us&edition=fundamental","pubTime":"2025-04-01 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newslet","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nL6N3QB0IK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GHLD","3NVD.UK","NVD3.UK","PTCT","NVDU","AGX","MIST","MRK","LGMK","NVDD","BEAM","GME","NVD2.UK","NVDY","NVD","OXM","LUV","CVAC","DTC","SGHC","CPT","X","NVDS.UK","2NVD.UK","NEM","ENPH","AU","LXRX","ON","WRB","NVIW.SI","AIR","ECX","LDOS","SNVD.UK","NVDX","WOLF","NVDS","XPO","STSS"],"gpt_icon":1},{"id":"2523268671","title":"Milestone Pharmaceuticals Price Target Maintained With a $25.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2523268671","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523268671?lang=en_us&edition=fundamental","pubTime":"2025-03-29 01:47","pubTimestamp":1743184020,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/MIST/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 28, 2025 13:47 ET (17:47 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIST"],"gpt_icon":0},{"id":"2523500809","title":"Dow Tumbles Over 500 Points; Abacus Global Management Shares Spike Higher","url":"https://stock-news.laohu8.com/highlight/detail?id=2523500809","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523500809?lang=en_us&edition=fundamental","pubTime":"2025-03-29 00:14","pubTimestamp":1743178491,"startTime":"0","endTime":"0","summary":" ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/25/03/44540623/dow-tumbles-over-500-points-abacus-global-management-shares-spike-higher","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["USAW.SI","IE00B19Z4B17.USD","BK4134","PCOM","XTIA","BK4139","USJW.SI","PRTG","AIR","TSYW.SI","MNQmain","BK4572","IE00B66KJ199.SGD","BK4173","IE0031619046.USD",".IXIC","NQmain","MIST","IE00B7SZL793.SGD","NVIW.SI","BK4187","ABL","DBVT","PSQ","QID","QLD","BK4122","TQQQ","BK4007","SQQQ"],"gpt_icon":1},{"id":"2522501719","title":"Piper Sandler Adjusts Price Target on Milestone Pharmaceuticals to $4 From $5, Maintains Overweight Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2522501719","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522501719?lang=en_us&edition=fundamental","pubTime":"2025-03-28 23:13","pubTimestamp":1743174796,"startTime":"0","endTime":"0","summary":"Milestone Pharmaceuticals (MIST) has an average rating of buy and mean price target of $10, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from ma","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["MIST"],"gpt_icon":0},{"id":"2522577404","title":"Milestone Pharmaceuticals Shares Down 64.7% After FDA Declines to Approve Co's Heart Rhythm Nasal Spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522577404","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522577404?lang=en_us&edition=fundamental","pubTime":"2025-03-28 21:34","pubTimestamp":1743168863,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nFWN3QB0L6:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522578087","title":"BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVT","url":"https://stock-news.laohu8.com/highlight/detail?id=2522578087","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522578087?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:53","pubTimestamp":1743162834,"startTime":"0","endTime":"0","summary":"BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVTMarch 28 (Reuters) - Milestone Pharmaceuticals Inc MIST.O:FDA ISSUES COMPLETE RESPONSE LETTER FOR ETRIPAMIL FOR PSVTMILESTONE PHARMACEUT","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nTUA2SXRZ8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","MIST"],"gpt_icon":1},{"id":"2522157850","title":"BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522157850","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522157850?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:46","pubTimestamp":1743162374,"startTime":"0","endTime":"0","summary":"BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray** Shares of drug developer Milestone Pharmaceuticals MIST.O fall 62.7% to 84 cents premarket** US FDA declined to approve MIST's nasal spray, Cardamyst, to treat a type of heart condition, company says** FDA raised no concerns about clinical safety or efficacy, but highlighted two key chemistry, manufacturing and controls issues - MIST** Issues include needing additional information on nitrosamine impurities, cancer-causing compounds formed during manufacturing and an inspection of a testing facility** Shares up 25% in the last 12 months, as of last close  ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nL3N3QB0W1:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIST","BK4007"],"gpt_icon":0},{"id":"2522520175","title":"Milestone Pharmaceuticals Shares Down 60% Premarket After FDA Declines to Approve Co's Heart Rhythm Nasal Spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522520175","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522520175?lang=en_us&edition=fundamental","pubTime":"2025-03-28 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19:20","pubTimestamp":1743160800,"startTime":"0","endTime":"0","summary":"The Food and Drug Administration has turned away a proposed nasal spray from Milestone Pharmaceuticals to treat a type of irregular heartbeat over concerns about how the drug is manufactured.Milestone said Friday that the FDA has issued a so-called complete response letter for the drug, etripamil, indicating the agency won't approve the application in its current form and called for additional studies.The Montreal biopharmaceutical company, which was seeking FDA approval of etripamil for the conversion of acute episodes of paroxysmal supraventricular tachycardia, or PSVT, to sinus rhythm in adults, said the agency didn't raise any concerns about the drug's clinical safety or efficacy data, but flagged two key chemistry, manufacturing and controls issues to be addressed.Milestone said the FDA requested additional information on nitrosamine impurities based on new draft guidance issued after the company filed its 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