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Milestone Pharmaceuticals Inc.

0.8001

-0.0799-9.08%

Post-market: 0.7897-0.0104-1.30%19:59 EDT

Volume:5.14M

Turnover:4.19M

Market Cap:42.69M

PE:-1.06

High:0.8800

Open:0.8800

Low:0.7800

Close:0.8800

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Overview Company News Filings

BUZZ-U.S. STOCKS ON THE MOVE-GameStop, Oxford Industries, Wolfspeed

Milestone Pharmaceuticals Price Target Maintained With a $25.00/Share by HC Wainwright & Co.

Dow Tumbles Over 500 Points; Abacus Global Management Shares Spike Higher

Piper Sandler Adjusts Price Target on Milestone Pharmaceuticals to $4 From $5, Maintains Overweight Rating

MT Newswires Live

Milestone Pharmaceuticals Shares Down 64.7% After FDA Declines to Approve Co's Heart Rhythm Nasal Spray

THOMSON REUTERS

BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVT

BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray

Milestone Pharmaceuticals Shares Down 60% Premarket After FDA Declines to Approve Co's Heart Rhythm Nasal Spray

THOMSON REUTERS

FDA Rejects Milestone Pharmaceuticals' Etripamil Nasal Spray

US FDA declines to approve Milestone Pharma's heart rhythm nasal spray

Milestone Pharmaceuticals Inc - Inspection Required at Facility Performing Etripamil Release Testing

THOMSON REUTERS

Milestone Pharmaceuticals Inc - FDA Raises No Concerns on Etripamil Clinical Safety or Efficacy

THOMSON REUTERS

Milestone Pharmaceuticals Inc - Company to Submit Additional Info on Nitrosamine Impurities

THOMSON REUTERS

FDA Issues Complete Response Letter for Etripamil for PSVT

Milestone Pharmaceuticals Inc - Enters Amended and Restated Open Market Sale Agreement With Jefferies - SEC Filing

THOMSON REUTERS

Milestone Pharmaceuticals Price Target Maintained With a $25.00/Share by HC Wainwright & Co.

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21:34","pubTimestamp":1743168863,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nFWN3QB0L6:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522578087","title":"BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVT","url":"https://stock-news.laohu8.com/highlight/detail?id=2522578087","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522578087?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:53","pubTimestamp":1743162834,"startTime":"0","endTime":"0","summary":"BRIEF-FDA Issues Complete Response Letter For Etripamil For PSVTMarch 28 (Reuters) - Milestone Pharmaceuticals Inc MIST.O:FDA ISSUES COMPLETE RESPONSE LETTER FOR ETRIPAMIL FOR PSVTMILESTONE PHARMACEUT","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nTUA2SXRZ8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","MIST"],"gpt_icon":1},{"id":"2522157850","title":"BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522157850","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522157850?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:46","pubTimestamp":1743162374,"startTime":"0","endTime":"0","summary":"BUZZ-Milestone Pharma slumps after FDA declines to approve heart rhythm nasal spray** Shares of drug developer Milestone Pharmaceuticals MIST.O fall 62.7% to 84 cents premarket** US FDA declined to approve MIST's nasal spray, Cardamyst, to treat a type of heart condition, company says** FDA raised no concerns about clinical safety or efficacy, but highlighted two key chemistry, manufacturing and controls issues - MIST** Issues include needing additional information on nitrosamine impurities, cancer-causing compounds formed during manufacturing and an inspection of a testing facility** Shares up 25% in the last 12 months, as of last close  ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nL3N3QB0W1:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522520175","title":"Milestone Pharmaceuticals Shares Down 60% Premarket After FDA Declines to Approve Co's Heart Rhythm Nasal Spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522520175","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522520175?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:32","pubTimestamp":1743161554,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nFWN3QB0K7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522527170","title":"FDA Rejects Milestone Pharmaceuticals' Etripamil Nasal Spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522527170","media":"Dow Jones","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522527170?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:20","pubTimestamp":1743160800,"startTime":"0","endTime":"0","summary":"The Food and Drug Administration has turned away a proposed nasal spray from Milestone Pharmaceuticals to treat a type of irregular heartbeat over concerns about how the drug is manufactured.Milestone said Friday that the FDA has issued a so-called complete response letter for the drug, etripamil, indicating the agency won't approve the application in its current form and called for additional studies.The Montreal biopharmaceutical company, which was seeking FDA approval of etripamil for the conversion of acute episodes of paroxysmal supraventricular tachycardia, or PSVT, to sinus rhythm in adults, said the agency didn't raise any concerns about the drug's clinical safety or efficacy data, but flagged two key chemistry, manufacturing and controls issues to be addressed.Milestone said the FDA requested additional information on nitrosamine impurities based on new draft guidance issued after the company filed its new-drug application for etripamil.The company said the FDA is also requiri","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"FDA Rejects Milestone Pharmaceuticals' Etripamil Nasal Spray","news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","MIST"],"gpt_icon":1},{"id":"2522522661","title":"US FDA declines to approve Milestone Pharma's heart rhythm nasal spray","url":"https://stock-news.laohu8.com/highlight/detail?id=2522522661","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522522661?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:03","pubTimestamp":1743159785,"startTime":"0","endTime":"0","summary":"US FDA declines to approve Milestone Pharma's heart rhythm nasal sprayMarch 28  - The U.S. Food and Drug Administration has declined to approve Milestone Pharmaceuticals' MIST.O nasal spray to treat a type of heart condition, the company said on Friday.      ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nL3N3QB0TL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522952409","title":"Milestone Pharmaceuticals Inc - Inspection Required at Facility Performing Etripamil Release Testing","url":"https://stock-news.laohu8.com/highlight/detail?id=2522952409","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522952409?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:00","pubTimestamp":1743159600,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nTUA2SXRZ8:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["MIST","BK4007"],"gpt_icon":0},{"id":"2522752408","title":"Milestone Pharmaceuticals Inc - FDA Raises No Concerns on Etripamil Clinical Safety or Efficacy","url":"https://stock-news.laohu8.com/highlight/detail?id=2522752408","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522752408?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:00","pubTimestamp":1743159600,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nTUA2SXRZ8:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522524060","title":"Milestone Pharmaceuticals Inc - Company to Submit Additional Info on Nitrosamine Impurities","url":"https://stock-news.laohu8.com/highlight/detail?id=2522524060","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522524060?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:00","pubTimestamp":1743159600,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250328:nTUA2SXRZ8:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","MIST"],"gpt_icon":0},{"id":"2522226555","title":"FDA Issues Complete Response Letter for Etripamil for PSVT","url":"https://stock-news.laohu8.com/highlight/detail?id=2522226555","media":"GlobeNewswire","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522226555?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:00","pubTimestamp":1743159600,"startTime":"0","endTime":"0","summary":"CRL focused on CMC; no clinical issues relating to etripamil raised. $69.7M in cash, cash equivalents and short-term investments as of December 31, 2024. MONTREAL and CHARLOTTE, N.C., March 28, 2025  -- Milestone Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration  issued a Complete Response Letter  regarding its New Drug Application  for CARDAMYST  nasal spray, a prescription medication in development for the conversion of acute episodes of PSVT to sinus rhythm in adults.The FDA did not raise any concerns regarding etripamil clinical safety or efficacy data and highlighted two key Chemistry, Manufacturing and Controls  issues to be addressed:. Company to submit additional information on nitrosamine impurities based on new draft guidance issued after the NDA submission; and","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/fda-issues-complete-response-letter-110000561.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0882574139.USD","BK4588","IE00BKVL7J92.USD","LU0149725797.USD","IE00BZ1G4Q59.USD","CMC","CRL","BK4530","LU1363072403.SGD","MIST","LU0267386448.USD","BK4121","IE00BHPRN162.USD","BK4007","LU0170899867.USD","IE00B1BXHZ80.USD","LU0971096721.USD","LU0390134368.USD","BK4585","BK4006"],"gpt_icon":0},{"id":"2520932437","title":"Milestone Pharmaceuticals Inc - Enters 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