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Opthea Ltd

3.41

+0.0000

Volume:- -

Turnover:- -

Market Cap:524.84M

PE:-1.62

High:3.41

Open:3.41

Low:3.41

Close:3.41

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Overview Company News Filings

Ocean Power Technologies Signs Strategic Reseller Agreement with Elektron SAS

Hearts and Minds Investments Portfolio Falls Nearly 9% in March

MT Newswires Live

Thursday’s HotCopper Trends: Sayona merger, Opthea slashes jobs | April 10, 2025

The Market Herald

Opthea Cuts 65% Staff, Terminates Drug Trials

MT Newswires Live

Opthea, with shares still suspended, cuts workforce by 65% after drug trials cancelled

The Market Herald

Ocean Power Technologies Highlights Supply Chain Resilience Amid Global Uncertainty

Broker laments 'catastrophic negative surprise' that highlights the risks with these types of ASX shares

This ASX share potentially 'has no value from here', says broker

Opthea Limited (CKDXF) was downgraded to a Sell Rating at Bell Potter

Hearts and Minds Investments Writes Down Opthea Holding to Zero

MT Newswires Live

Health Check: FDA casualties mount as Trump’s ‘revolution’ takes place

Market Chatter: Regal Takes Responsibility for Opthea Investment Losses

MT Newswires Live

Opthea Ends Development of Sozinibercept in Wet AMD

Opthea Terminates Sozinibercept Development After Failed Phase 3 Trials

MT Newswires Live

Opthea terminates COAST trial, announces ShORe trial misses endpoint

Opthea in active talks with funders after second trial fails

The Australian Financial Review

Opthea Announces Decision to Discontinue Wet AMD Trials

Opthea Halts Wet AMD Trials Following Unsuccessful Phase 3 Results

Scott Power: ASX health sector down in week of good and bad news

HotCopper Highlights for Week 13 – Opthea, Reject Shop, Bellevue & more!

The Market Herald

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One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/stock/OPT/news"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"OPT","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"OPT\",,,,,undefined,":{"symbol":"OPT","market":"US","secType":"STK","nameCN":"Opthea Ltd","latestPrice":3.41,"timestamp":1744920000000,"preClose":3.41,"halted":3,"volume":0,"delay":0,"floatShares":98250942,"shares":153910917,"eps":-2.105144,"marketStatus":"Halted","change":0,"latestTime":"04-17 16:00:00 EDT","open":3.41,"high":3.41,"low":3.41,"amount":0,"amplitude":0,"askPrice":0,"askSize":0,"bidPrice":0,"bidSize":0,"shortable":3,"etf":0,"ttmEps":-2.105144,"tradingStatus":0,"nextMarketStatus":{"tag":"Pre-Mkt","tradingStatus":1,"beginTime":1745222400000},"marketStatusCode":7,"adr":0,"adrRate":8,"listingDate":1602820800000,"exchange":"NASDAQ","adjPreClose":3.41,"volumeRatio":0.09062095562326103},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"OPT\",,,,,undefined,":{"symbol":"OPT","floatShares":98250942,"roa":"-73.34%","roe":"-3383.08%","lyrEps":-2.760776,"volumeRatio":0.09062095562326103,"shares":153910917,"dividePrice":0,"high":3.41,"amplitude":0,"preClose":3.41,"low":3.41,"week52Low":1.79,"pbRate":"-3.11","psRate":"2512.87","week52High":6.3,"institutionHeld":0,"latestPrice":3.41,"eps":-2.105144,"divideRate":0,"volume":0,"delay":0,"ttmEps":-2.105144,"open":3.41,"prevYearClose":3.9275,"prevWeekClose":3.41,"prevMonthClose":3.41,"prevQuarterClose":3.41,"fiveDayClose":3.41,"twentyDayClose":3.41,"sixtyDayClose":4.41},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"OPT\",pageSize:20,pageCount:1,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2526665231","title":"Ocean Power Technologies Signs Strategic Reseller Agreement with Elektron SAS","url":"https://stock-news.laohu8.com/highlight/detail?id=2526665231","media":"GlobeNewswire","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526665231?lang=en_us&edition=fundamental","pubTime":"2025-04-11 20:15","pubTimestamp":1744373700,"startTime":"0","endTime":"0","summary":"Expands Commercial Reach of Intelligent Maritime Solutions Across Latin AmericaMONROE TOWNSHIP, N.J., April  11, 2025  (GLOBE NEWSWIRE) -- Ocean Power Technologies, Inc. (NYSE American: OPTT) (“OPT” o","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/04/11/3060063/9069/en/Ocean-Power-Technologies-Signs-Strategic-Reseller-Agreement-with-Elektron-SAS.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OPT","BK4182","OPTT","BK4139"],"gpt_icon":0},{"id":"2526524680","title":"Hearts and Minds Investments Portfolio Falls Nearly 9% in March","url":"https://stock-news.laohu8.com/highlight/detail?id=2526524680","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526524680?lang=en_us&edition=fundamental","pubTime":"2025-04-11 08:19","pubTimestamp":1744330743,"startTime":"0","endTime":"0","summary":"Hearts and Minds Investments'  portfolio declined 8.9% in March, bigger than the MSCI World Index's 5.2% drop in the same month, according to a Friday filing with the Australian bourse.The decline occurred as equity markets faced volatility during the month amid uncertainties about US trade policies, the filing said.The investment company also saw the unsuccessful outcome of Opthea's  phase 3 clinical trials for its lead drug candidate, OPT-302. This prompted Hearts & Minds to write down its investment to zero.Before its trading suspension, Opthea represented around 2.4% of Hearts and Minds Investments' portfolio, per a Tuesday statement.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7067","BK4139","HM1.AU","BK7508","OPT","OPT.AU"],"gpt_icon":0},{"id":"2526776643","title":"Thursday’s HotCopper Trends: Sayona merger, Opthea slashes jobs | April 10, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2526776643","media":"The Market Herald","labels":["merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526776643?lang=en_us&edition=fundamental","pubTime":"2025-04-10 11:04","pubTimestamp":1744254240,"startTime":"0","endTime":"0","summary":"The ASX has been up, charging 4.7% higher at around 7,720 points today.Sayona Mining  has been among the most watched on HotCopper forums on news it has merged with NASDAQ-listed Piedmont Lithium. The name of the company will be changed to Elevra Lithium once the deal closes.Sayona Mining has been 1.6 cents in early afternoon trades.BOSS Energy  has also been trending on the forums after presenting at the Resources Rising Stars conference today. The company shared actual production and sales results for Q3 FY25.Finally, Opthea  shared a corporate update after the termination of its COAST Phase 3 clinical trials. In light of the negative trial results, the Board has decided to reduce costs and has slashed 65% of the workforce.Join the discussion: See what’s trending right now on HotCopper, Australia’s largest stock forum, and be part of the conversations that move the markets.The material provided in this article is for information only and should not be treated as investment advice. Vi","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://themarketonline.com.au/thursdays-hotcopper-trends-sayona-merger-opthea-slashes-jobs-april-10-2025-2025-04-10/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"merge","news_rank":0,"length":0,"strategy_id":0,"source":"markerherald_stock","symbols":["BK7508","BK7067","OPT","BK7083","BOE.AU","BK4139","BK7095","OPT.AU","SYA.AU","BK7504"],"gpt_icon":0},{"id":"2526324926","title":"Opthea Cuts 65% Staff, Terminates Drug Trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2526324926","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526324926?lang=en_us&edition=fundamental","pubTime":"2025-04-10 09:16","pubTimestamp":1744247818,"startTime":"0","endTime":"0","summary":"Opthea  has terminated phase three clinical trials for two of its drug candidates following negative results, according to a Thursday Australian bourse filing.The company will be reducing its workforce by about 65% to cut costs while retaining a limited number of employees to ensure compliant termination of clinical trial activities and oversee administrative operations, the filing added.The company expects the workforce reduction to take effect from May 1 with one-off costs of about $4.5 million, resulting reduction in monthly employee costs of $1 million.The company sees unaudited cash and cash equivalents of $100 million at the end of March.The company said its ability to continue as a going concern remains materially uncertain.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7067","OPT.AU","BK7508","BK4139","OPT"],"gpt_icon":0},{"id":"2526129322","title":"Opthea, with shares still suspended, cuts workforce by 65% after drug trials cancelled","url":"https://stock-news.laohu8.com/highlight/detail?id=2526129322","media":"The Market Herald","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526129322?lang=en_us&edition=fundamental","pubTime":"2025-04-10 09:07","pubTimestamp":1744247220,"startTime":"0","endTime":"0","summary":"Troubled biotech stock Opthea , still in the process of crisis talks with investors, has flagged a workforce reduction of -65%.Listen to the HotCopper podcast for in-depth discussions and insights on all the biggest headlines from throughout the week. On Spotify, Apple, and more.This comes not long after Opthea’s flagship Phase 3 trial treating age-related vision loss came up empty-handed because its drug of interest simply wasn’t proven to be effective.Those results prompted Opthea to abandon not one, but two trials; and now, what was a former favourite among HotCopper‘s myriad biotech watchers, is quickly becoming a letdown.Probably nobody is more aware of this than Opthea.“As previously disclosed, the company remains in active negotiations with its [keystone] investors… to explore possible options to deliver the best outcome for the company and its shareholders,” the company wrote.The material provided in this article is for information only and should not be treated as investment a","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://themarketonline.com.au/opthea-with-shares-still-suspended-cuts-workforce-by-65-after-drug-trials-cancelled-2025-04-10/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"markerherald_stock","symbols":["BK7067","OPT.AU","OPT","BK7508","BK4139"],"gpt_icon":0},{"id":"2525017041","title":"Ocean Power Technologies Highlights Supply Chain Resilience Amid Global Uncertainty","url":"https://stock-news.laohu8.com/highlight/detail?id=2525017041","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525017041?lang=en_us&edition=fundamental","pubTime":"2025-04-07 20:15","pubTimestamp":1744028100,"startTime":"0","endTime":"0","summary":"Majority Domestic Supply Chain Enables OperationalContinuity and Competitive AdvantageMONROE TOWNSHIP, N.J., April  07, 2025  (GLOBE NEWSWIRE) -- Ocean Power Technologies, Inc. (\"OPT\" or the \"Company\"","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/04/07/3056702/9069/en/Ocean-Power-Technologies-Highlights-Supply-Chain-Resilience-Amid-Global-Uncertainty.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OPT","BK4139","OPTT","BK4182"],"gpt_icon":0},{"id":"2525222758","title":"Broker laments 'catastrophic negative surprise' that highlights the risks with these types of ASX shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2525222758","media":"MotleyFool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525222758?lang=en_us&edition=fundamental","pubTime":"2025-04-05 04:00","pubTimestamp":1743796800,"startTime":"0","endTime":"0","summary":"ASX share Opthea Limited (ASX: OPT)remains suspended from trading as the biotechcompany works to avoid insolvency.  Opthea last traded at 60 cents per share.   Last week, we learned that Opthea has de","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com.au/2025/04/05/broker-laments-catastrophic-negative-surprise-that-highlights-the-risks-with-these-types-of-asx-shares/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"motleyfoolau_stock","symbols":["BK7511","BK7501","BK7508","BK7067","OPT","XJO.AU","MSB.AU","BK4139","OPT.AU","CSL.AU"],"gpt_icon":0},{"id":"2524227858","title":"This ASX share potentially 'has no value from here', says broker","url":"https://stock-news.laohu8.com/highlight/detail?id=2524227858","media":"MotleyFool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524227858?lang=en_us&edition=fundamental","pubTime":"2025-04-04 12:55","pubTimestamp":1743742507,"startTime":"0","endTime":"0","summary":"The ASX biotech advised investors on 24 March that its Phase 3 COAST clinical trial of OPT-302 had failed to meet its primary endpoint.  The trial was assessing sozinibercept  combined with aflibercept to treat wet AMD. The failure of the trial raised serious financial concerns for Opthea. The company said it would review its obligations under its Development Funding Agreement  with key investors to decide the next steps.  What's the latest news with this ASX biotech share?Importantly, Opthea and its DFA investors have agreed that ceasing both trials does not constitute a 'termination event' under the DFA. This means Opthea does not","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com.au/2025/04/04/this-asx-share-potentially-has-no-value-from-here-says-broker/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"motleyfoolau_stock","symbols":["LU1880398471.USD","LU1989764664.SGD","LU0719512351.SGD","LU1951200564.SGD","LU0198837287.USD","LU1803068979.SGD","LU2264538146.SGD","LU1303367103.USD","LU1852331112.SGD","LU1988902786.USD","LU0056508442.USD","LU0979878070.USD","LU1951198990.SGD","BK4139","LU0823421333.USD","BK7067","LU0127658192.USD","BK4588","BK4512","LU1064131342.USD","LU0109392836.USD","LU1316542783.SGD","IE0009356076.USD","IE00BMPRXR70.SGD","LU2054465674.USD","LU2458330243.SGD","LU2360106780.USD","LU2458330169.SGD","BK4585","GFS","IE00B5949003.HKD","LU1242518931.SGD","LU0390134368.USD","OPT.AU","BK4605","LU0642271901.SGD","BK4575","BK4573","BK4141","LU0823434583.USD","BK4612","IE0004445239.USD","BK7508","BK4529","BK4566","LU0082616367.USD","LU0823434740.USD","OPT","BK4534"],"gpt_icon":1},{"id":"2524494180","title":"Opthea Limited (CKDXF) was downgraded to a Sell Rating at Bell Potter","url":"https://stock-news.laohu8.com/highlight/detail?id=2524494180","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524494180?lang=en_us&edition=fundamental","pubTime":"2025-04-02 21:55","pubTimestamp":1743602149,"startTime":"0","endTime":"0","summary":"Opthea Limited (CKDXF – Research Report) received a Sell rating and a A$0.05 price target from Bell Potter analyst Thomas Wakim yesterday. The comp...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/opthea-limited-ckdxf-was-downgraded-to-a-sell-rating-at-bell-potter?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/opthea-limited-ckdxf-was-downgraded-to-a-sell-rating-at-bell-potter?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OPT","CKDXF"],"gpt_icon":0},{"id":"2524548879","title":"Hearts and Minds Investments Writes Down Opthea Holding to Zero","url":"https://stock-news.laohu8.com/highlight/detail?id=2524548879","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524548879?lang=en_us&edition=fundamental","pubTime":"2025-04-02 12:03","pubTimestamp":1743566613,"startTime":"0","endTime":"0","summary":"Hearts and Minds Investments  said its board decided to write down the value of its portfolio holding in Opthea  to zero, effective Monday, according to a Wednesday Australian bourse filing.The board had previously written down the value of the holding to AU$0.20 per share.The write-down will negatively impact the net asset value of the firm by around AU$0.034 per share, the filing said.This move comes after Opthea said that its second phase three trial of a treatment for an eye disease had failed.Hearts and Minds Investments' shares jumped past 1% in recent trading on Wednesday.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["HM1.AU","BK4139","OPT","OPT.AU","BK7067","BK7508"],"gpt_icon":0},{"id":"2524854804","title":"Health Check: FDA casualties mount as Trump’s ‘revolution’ takes place","url":"https://stock-news.laohu8.com/highlight/detail?id=2524854804","media":"Stockheads","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524854804?lang=en_us&edition=fundamental","pubTime":"2025-04-02 10:14","pubTimestamp":1743560055,"startTime":"0","endTime":"0","summary":"The guillotines are swooshing at the FDA as a reported 3500 staff get the chop. Grisly tales are emerging from the corridors of the US Food & Drug Administration  as mass sackings take effect.The purge reportedly affects 3500 staff, 19% of the agency’s workforce.“The revolution begins today” posted new health secretary Robert F Kennedy Junior on X.As with the French revolution, the tumbrils are rapidly filling.Endpoints News reports employees turned up at the FDA’s main Maryland campus, only to find their badges – and jobs – were gone.Center for Biologics Evaluation and Research  chief Peter Marks is departing, citing an “unprecedented assault on scientific truth”..CBER Office of New Drugs director Peter Stein said he was offered “inappropriate” reassignment choices and quit.Other departees include FDA chief medical officer Hilary Marston and tobacco director Brian King.Across the broader Health and Human Services  department, the toe cutters have given some senior leaders the choice t","market":"us","thumbnail":"https://stockhead.com.au/wp-content/uploads/2025/04/GettyImages-1484803165-1200x675-1-640x360.jpg","type":0,"news_type":0,"thumbnails":["https://stockhead.com.au/wp-content/uploads/2025/04/GettyImages-1484803165-1200x675-1-640x360.jpg"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://stockhead.com.au/health/health-check-fda-casualties-mount-as-trumps-revolution-takes-place/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"stockheads_stock","symbols":["HHS","BK4139","OPT","BK4009"],"gpt_icon":0},{"id":"2524177853","title":"Market Chatter: Regal Takes Responsibility for Opthea Investment Losses","url":"https://stock-news.laohu8.com/highlight/detail?id=2524177853","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524177853?lang=en_us&edition=fundamental","pubTime":"2025-04-02 09:23","pubTimestamp":1743557031,"startTime":"0","endTime":"0","summary":"Regal Investment Fund  Chief Investment Officer Phil King has taken responsibility for the firm's losses stemming from its investment in Opthea , the Australian Financial Review reported Wednesday, citing a letter to investors.Opthea has said that its study of the combination of OPT-302 and aflibercept in patients with age-related macular degeneration failed to meet its primary endpoint, prompting it to terminate the study. It also added that there is \"significant\" doubt about its ability to continue as a going concern.Regal, which held a 30% stake in Opthea, has written down the investment to zero, acknowledging the blow to investor returns across several funds, the report said.The loss is expected to \"significantly\" affect the performance of Regal's long and short equity strategies for March, the report said.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RF1.AU","BK7508","BK7067","OPT","OPT.AU","BK4139"],"gpt_icon":0},{"id":"2523420469","title":"Opthea Ends Development of Sozinibercept in Wet AMD","url":"https://stock-news.laohu8.com/highlight/detail?id=2523420469","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523420469?lang=en_us&edition=fundamental","pubTime":"2025-03-31 21:37","pubTimestamp":1743428220,"startTime":"0","endTime":"0","summary":"Opthea is scrapping development of lead product candidate sozinibercept in wet age-related macular degeneration, or wet AMD, following the failure of another late-stage study.Opthea on Monday said its second Phase 3 study of sozinibercept in combination with aflibercept in wet AMD, an eye condition that causes blurred vision or reduced central vision, missed its primary endpoint of mean change in best corrected visual acuity.The clinical-stage biopharmaceutical company said it opted to accelerate the study readout following the similar Phase 3 study failure it reported last week.Opthea said it agreed with the investors in its development funding agreement to end development of sozinibercept in wet AMD, and that the move wouldn't constitute a termination event under the funding deal.However, the company warned once again that it might be required to pay amounts to the investors--which would have a material adverse effect on its solvency--and that there is material uncertainty about its ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4605","LU0127658192.USD","LU1923623000.USD","LU0823421416.USD","LU0823434583.USD","LU2264538146.SGD","LU0082616367.USD","LU0889565833.HKD","BK4534","BK4529","OPT","LU1988902786.USD","BK4512","LU2458330169.SGD","LU0823434740.USD","LU2458330243.SGD","BK4532","LU1242518931.SGD","IE00B5949003.HKD","LU2250418816.HKD","LU1803068979.SGD","LU1951198990.SGD","LU2098885051.SGD","BK7508","LU0198837287.USD","GFS","OPT.AU","LU0081259029.USD","LU2054465674.USD","BK4573","BK4588","LU0979878070.USD","IE0009356076.USD","IE00BMPRXN33.USD","LU0823421333.USD","LU1242518857.USD","LU0109392836.USD","LU0056508442.USD","LU0390134368.USD","IE00BMPRXR70.SGD","BK4585","LU1880398554.USD","BK4139","BK4575","LU1064131342.USD","LU1989764664.SGD","IE0004445239.USD","LU1316542783.SGD","BK4543"],"gpt_icon":1},{"id":"2523956912","title":"Opthea Terminates Sozinibercept Development After Failed Phase 3 Trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2523956912","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523956912?lang=en_us&edition=fundamental","pubTime":"2025-03-31 18:58","pubTimestamp":1743418697,"startTime":"0","endTime":"0","summary":"Opthea  said Monday that a phase 3 trial evaluating the efficacy and safety of 2 mg sozinibercept for wet age-related macular degeneration failed to meet its primary endpoint of improved visual acuity.The announcement is the second blow for the company as another phase 3 failed to meet its primary goal last week.Opthea and its Development Funding Agreement investors have agreed to immediately discontinue the development of sozinibercept for wet age-related macular degeneration, the company said.It added that the decision does not trigger a termination event under the  Development Funding Agreement, meaning no payment is required to be made by Opthea.The company said it continues discussions with  Development Funding Agreement investors to explore potential options for its future.Opthea estimates it will have $100 million in cash and cash equivalents by the end of March 2025 but faces uncertainty about its ability to continue as a going concern, the drug developer said.The ASX will susp","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","OPT","BK7067","BK7508","OPT.AU"],"gpt_icon":0},{"id":"2523916040","title":"Opthea terminates COAST trial, announces ShORe trial misses endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2523916040","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523916040?lang=en_us&edition=fundamental","pubTime":"2025-03-31 17:45","pubTimestamp":1743414319,"startTime":"0","endTime":"0","summary":"Opthea (OPT) announced updates on its Phase 3 clinical program, including the termination of COAST and accelerated topline results from its second ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/opthea-terminates-coast-trial-announces-shore-trial-misses-endpoint?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/opthea-terminates-coast-trial-announces-shore-trial-misses-endpoint?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","OPT"],"gpt_icon":0},{"id":"2523564962","title":"Opthea in active talks with funders after second trial fails","url":"https://stock-news.laohu8.com/highlight/detail?id=2523564962","media":"The Australian Financial Review","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523564962?lang=en_us&edition=fundamental","pubTime":"2025-03-31 14:52","pubTimestamp":1743403920,"startTime":"0","endTime":"0","summary":"ASX-listed biotech Opthea says it has terminated the second of its two trials of drugs to treat a common eye disease, delivering a near mortal blow to shareholders who had already written down the majority of their investments.The company said on Monday that a second phase 3 trial “did not meet its primary endpoint” after disappointing investors only last week with the news that a first phase 3 trial had failed.Loading...","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.afr.com/markets/equity-markets/opthea-in-active-talks-with-funders-after-second-trial-fails-20250331-p5lnx7","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"afr_stock","symbols":["OPT"],"gpt_icon":0},{"id":"2523951735","title":"Opthea Announces Decision to Discontinue Wet AMD Trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2523951735","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523951735?lang=en_us&edition=fundamental","pubTime":"2025-03-31 12:01","pubTimestamp":1743393660,"startTime":"0","endTime":"0","summary":"ShORe Phase 3 topline results accelerated; trial did not meet primary endpoint of mean change in BCVA from baseline to week 52. Opthea and DFA Investors agreed to terminate both COAST and ShORe trials. Opthea continues to consider impact of negative trial results under its Development Funding Agreement  and on the Company as a going concern. The global ShORe Phase 3 trial evaluated the efficacy and safety of intravitreally administered 2 mg sozinibercept every four or eight weeks in combination with 0.5 mg ranibizumab every four weeks, as per label, versus 0.5 mg ranibizumab monotherapy. The trial did not meet its primary endpoint of mean change in best corrected visual acuity  from baseline to week 52.“We are disappointed that COAST and ShORe did not demonstrate the improvements in vision with sozinibercept combination therapy compared to standard of care that we had hoped for,” said Frederic Guerard, PharmD, Chief Executive Officer of Opthea. “We are grateful to all patients, clinica","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/opthea-announces-decision-discontinue-wet-040100489.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4534","LU0127658192.USD","BK4605","BK4585","LU0082616367.USD","LU1880398471.USD","LU0390134368.USD","LU0081259029.USD","LU1923623000.USD","LU0823421416.USD","LU1989764664.SGD","BK4139","LU2360106780.USD","LU1803068979.SGD","LU1880398554.USD","BK4554","LU1064131342.USD","LU1951198990.SGD","BK4614","LU2458330169.SGD","LU2264538146.SGD","IE0004445239.USD","LU1852331112.SGD","OPT","LU1316542783.SGD","BK4141","BK4575","LU1303367103.USD","LU2054465674.USD","LU2250418816.HKD","BK4612","LU0823434583.USD","IE00B5949003.HKD","LU1242518857.USD","LU1988902786.USD","IE00BMPRXN33.USD","BK4529","BK4512","IE00BMPRXR70.SGD","LU0642271901.SGD","LU0823434740.USD","LU0889565833.HKD","LU0979878070.USD","LU2098885051.SGD","BK4573","LU0719512351.SGD","OPT.AU","BK4566","LU1951200564.SGD","GFS"],"gpt_icon":1},{"id":"2523956241","title":"Opthea Halts Wet AMD Trials Following Unsuccessful Phase 3 Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2523956241","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523956241?lang=en_us&edition=fundamental","pubTime":"2025-03-31 11:18","pubTimestamp":1743391097,"startTime":"0","endTime":"0","summary":"An announcement from Opthea Limited ( ($AU:OPT) ) is now available. Opthea Limited has announced the discontinuation of its Phase 3 trials, COAST a...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/opthea-halts-wet-amd-trials-following-unsuccessful-phase-3-results?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/opthea-halts-wet-amd-trials-following-unsuccessful-phase-3-results?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0823434740.USD","LU1880398471.USD","LU0390134368.USD","LU2250418816.HKD","BK4141","BK4566","LU0081259029.USD","LU0056508442.USD","LU1989764664.SGD","BK4532","LU1316542783.SGD","BK4554","LU1803068979.SGD","BK4612","LU1880398554.USD","LU1303367103.USD","LU2458330169.SGD","LU0719512351.SGD","BK4573","IE00B5949003.HKD","LU0823421333.USD","LU0082616367.USD","BK4588","BK4139","LU2054465674.USD","BK4614","LU0642271901.SGD","LU0823421416.USD","BK4534","LU1988902786.USD","LU2458330243.SGD","GFS","BK4512","LU1242518857.USD","IE00BMPRXR70.SGD","LU0979878070.USD","LU1064131342.USD","LU2360106780.USD","OPT","BK4605","IE00BMPRXN33.USD","LU1852331112.SGD","BK4529","IE0009356076.USD","LU0823434583.USD","LU0889565833.HKD","LU1242518931.SGD","LU2098885051.SGD","LU2264538146.SGD"],"gpt_icon":0},{"id":"2522512071","title":"Scott Power: ASX health sector down in week of good and bad news","url":"https://stock-news.laohu8.com/highlight/detail?id=2522512071","media":"Stockheads","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522512071?lang=en_us&edition=fundamental","pubTime":"2025-03-28 14:14","pubTimestamp":1743142455,"startTime":"0","endTime":"0","summary":"ASX heath sector falls 2.1%, while broader markets rise 0.8% for the same period. Opthea phase III Coast trial into wet AMD fails to meet primary and secondary endpoints. EMVision starts pivotal validation trial for emu bedside brain scanner to diagnose stroke","market":"hk","thumbnail":"https://stockhead.com.au/wp-content/uploads/2025/03/GettyImages-108225711-1200x675-1-640x360.jpg","type":0,"news_type":0,"thumbnails":["https://stockhead.com.au/wp-content/uploads/2025/03/GettyImages-108225711-1200x675-1-640x360.jpg"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://stockhead.com.au/health/scott-power-asx-health-sector-down-in-week-of-good-and-bad-news/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"stockheads_stock","symbols":["DHS","BK4084","BK4139","BK4213","BK4563","BK4168","PW","TMC","OPT","SOC","ASA","BK4234"],"gpt_icon":0},{"id":"2522058513","title":"HotCopper Highlights for Week 13 – Opthea, Reject Shop, Bellevue & more!","url":"https://stock-news.laohu8.com/highlight/detail?id=2522058513","media":"The Market Herald","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522058513?lang=en_us&edition=fundamental","pubTime":"2025-03-28 14:14","pubTimestamp":1743142440,"startTime":"0","endTime":"0","summary":"Good Afternoon and welcome to HotCopper Highlights, I’m Jonathon Davidson. This is where we highlight what you were watching and discussing most on the forums this week. Let’s get into it.Opthea Limitedattracted much attention this week after its Phase 3 trial results treating age-related vision loss came up empty handed – which is to say its flagship drug doesn’t work.This is the biotech equivalent of a gas company drilling a duster, and sentiment went about how you’d expect. Opthea is now in crisis talks with investors to figure out whether it should keep going, or just give up. Talk about a bummer.Meanwhile, Australian dollar storethe Reject Shoprocketed this week as a surprise buyout offer from a Canadian value retailer giant called Dollarama valued shares at nearly $6.70 cents each, which a price the Reject Shop has struggled to return to since February 2022.That’s HotCopper Highlights for this week, I’m Jonathon Davidson, have a great weekend and we’ll see you on 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