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The jump came on an impressive volume with a higher-than-average number of shares changing hands in the session. This compares to the stock's 3% loss over the past four weeks.The sudden increase in the stock price can be attributed to the growing investor optimism about the company’s set of novel pipeline candidates being developed for treating various oncological indications and other serious diseases.This company is expected to post quarterly loss of $2.33 per share in its upcoming report, which represents a year-over-year change of -64.1%. Revenues are expected to be $149.92 million, down 26.4% from the year-ago quarter.For BioNTech, the consensus EPS estimate for the quarter has been revised 13.8% higher over the last 30 days to the current level. And a positive trend in earnings estimate revision usually translates into price appreciation. 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