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cough count of 67% from baseline and 57% on a placebo-adjusted basis at day 21.Trevi said it plans to discuss the next steps with the US Food and Drug Administration and expects to initiate the next study after receiving the regulator's feedback.Shares of the company rose more than 32% in recent premarket activity.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["TRVI","LENZ","BK4007","BK4139"],"gpt_icon":0},{"id":"2518624420","title":"Trevi Therapeutics Is Maintained at Buy by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2518624420","media":"Dow 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$8","url":"https://stock-news.laohu8.com/highlight/detail?id=2518241613","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518241613?lang=en_us&edition=fundamental","pubTime":"2025-03-10 18:58","pubTimestamp":1741604331,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250310:nFWN3PT0D3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["TRVI","BK4007"],"gpt_icon":0},{"id":"2518497622","title":"BUZZ-Trevi jumps as chronic cough therapy succeeds mid-stage 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in the past ** Up to last close, TRVI up 45.8% in the last 12 months  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Cough","url":"https://stock-news.laohu8.com/highlight/detail?id=2518083245","media":"PR Newswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518083245?lang=en_us&edition=fundamental","pubTime":"2025-03-10 18:00","pubTimestamp":1741600800,"startTime":"0","endTime":"0","summary":"Haduvio met the primary endpoint with a statistically-significant reduction  in 24-hour cough frequency with a 57% placebo-adjusted change from baseline. Haduvio is the first and only therapy to show a statistically-significant reduction in chronic cough across both RCC and IPF patients. Patient reported and other secondary outcomes were statistically significant and consistent with the primary endpoint. NEW HAVEN, Conn.,  March 10, 2025  /PRNewswire/ -- Trevi Therapeutics, Inc. , a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio  for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis  and refractory chronic cough , is pleased to announce today positive topline results from its Phase 2a RIVER trial of Haduvio for the treatment of patients with RCC . Haduvio met the primary endpoint with a statistically-significant reduction in the objective 24-hour cough frequency of 67% from baseline and 57% on a placebo-adjusted basis","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/trevi-therapeutics-announces-positive-topline-100000072.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/trevi-therapeutics-announces-positive-topline-100000072.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TRVI","BK4585","BK4139","RCC","LENZ","FAS","BK4007","BK4588"],"gpt_icon":0},{"id":"2518249238","title":"Trevi Therapeutics to Host Conference Call and Webcast on March 10th to Share Topline Results from the Phase 2a RIVER Trial of Haduvio in Patients with Refractory Chronic Cough","url":"https://stock-news.laohu8.com/highlight/detail?id=2518249238","media":"PR Newswire","labels":["conferences","dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518249238?lang=en_us&edition=fundamental","pubTime":"2025-03-10 04:00","pubTimestamp":1741550400,"startTime":"0","endTime":"0","summary":"Conference call and webcast to be held at 8:30 a.m. ET. NEW HAVEN, Conn., March 9, 2025 /PRNewswire/ --Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio  for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis  and refractory chronic cough , today announced a conference call and live webcast taking place tomorrow, Monday, March 10th, 2025, at 8:30 a.m. ET, to share topline results from the Phase 2a RIVER trial of Haduvio in patients with refractory chronic cough.Chronic cough is highly prevalent in IPF patients, impacting up to 85% of the IPF population. There are ~140,000 U.S. IPF patients and the impact of chronic cough is significant with patients coughing up to 1,500 times per day. This consistent cough, and any associated damage, may lead to worsening disease, a higher risk of progression, death, or need for lung transplant. Chronic cough also often leads to a decline in patients' social, p","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/trevi-therapeutics-host-conference-call-200000325.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/trevi-therapeutics-host-conference-call-200000325.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences,dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4588","BK4218","BK4585","LENZ","BK4181","BK4139","BK4007","RCC","TRVI","HST"],"gpt_icon":0},{"id":"2514801863","title":"Trevi Therapeutics to Participate in Upcoming March Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2514801863","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514801863?lang=en_us&edition=fundamental","pubTime":"2025-02-27 20:30","pubTimestamp":1740659400,"startTime":"0","endTime":"0","summary":"NEW HAVEN, Conn., Feb. 27, 2025 /PRNewswire/ --Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio  for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis  and refractory chronic cough ,today announced that senior management will be attending the following investor conferences in March.Refractory chronic cough affects approximately 2-3 million adults in the U.S. and is caused by cough reflex hypersensitivity in both the central and peripheral nerves. It is a highly disruptive disease and accompanied by a wide range of complications, ranging from urinary incontinence in females to sleep disruption and social embarrassment that causes significant social and economic burdens for patients and those around them. There are also no approved therapies for RCC in the U.S.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/trevi-therapeutics-participate-upcoming-march-123000073.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/trevi-therapeutics-participate-upcoming-march-123000073.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","TRVI","BK4139","RCC","BK4007"],"gpt_icon":0},{"id":"2514045856","title":"B.Riley Financial Sticks to Its Buy Rating for Trevi Therapeutics (TRVI)","url":"https://stock-news.laohu8.com/highlight/detail?id=2514045856","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514045856?lang=en_us&edition=fundamental","pubTime":"2025-02-26 03:35","pubTimestamp":1740512114,"startTime":"0","endTime":"0","summary":"In a report released today, Mayank Mamtani from B.Riley Financial reiterated a Buy rating on Trevi Therapeutics (TRVI – Research Report), with a pr...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/b-riley-financial-sticks-to-its-buy-rating-for-trevi-therapeutics-trvi-3?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/b-riley-financial-sticks-to-its-buy-rating-for-trevi-therapeutics-trvi-3?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["TRVI"],"gpt_icon":0},{"id":"2514097035","title":"BRIEF-Trevi Therapeutics Completes Enrollment For Phase 2B Coral Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2514097035","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514097035?lang=en_us&edition=fundamental","pubTime":"2025-02-25 22:36","pubTimestamp":1740494205,"startTime":"0","endTime":"0","summary":"BRIEF-Trevi Therapeutics Completes Enrollment For Phase 2B Coral TrialFeb 25 (Reuters) - 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