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Shares have climbed almost 50% in 2025.Before resuming the trial, vTv plans to submit a protocol amendment to reduce the overall duration of the trial to six months from 12 months to expedite the initiation of required larger pivotal studies for future New Drug Application submissions. By shortening the trial, vTv can collect topline data from the study more quickly, it said. The planned change will not include the additional six-month period to collect safety data, vTv said.Cadisegliatin is an oral, liver selective glucokinase activator that's being investigated as an adjunctive treatment to insulin for type 1 diabetes. The company announced the Phase 3 trial in July. No patient had been dosed at the time of the clinical hold and past clinical studies did not reveal any concerning safety issues, vTv said.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","VTVT","LENZ"],"gpt_icon":0},{"id":"2520952739","title":"BUZZ-vTv jumps after FDA lifts clinical hold on diabetes therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2520952739","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520952739?lang=en_us&edition=fundamental","pubTime":"2025-03-17 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latest update is out from vTv Therapeutics ( ($VTVT) ). On February 24, 2025, vTv Therapeutics announced that Steven Tuch, its Executive Vice P...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/vtv-therapeutics-cfo-steven-tuch-to-resign?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/vtv-therapeutics-cfo-steven-tuch-to-resign?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","VTVT"],"gpt_icon":0},{"id":"2508138615","title":"We're Keeping An Eye On vTv Therapeutics' (NASDAQ:VTVT) Cash Burn Rate","url":"https://stock-news.laohu8.com/highlight/detail?id=2508138615","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508138615?lang=en_us&edition=fundamental","pubTime":"2025-02-02 20:36","pubTimestamp":1738499803,"startTime":"0","endTime":"0","summary":"Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the right price. For example, although Amazon.com made losses for many years after listing, if you had bought and held the shares since 1999, you would have made a fortune. But the harsh reality is that very many loss making companies burn through all their cash and go bankrupt.So, the natural question for vTv Therapeutics  shareholders is whether they should be concerned by its rate of cash burn. For the purposes of this article, cash burn is the annual rate at which an unprofitable company spends cash to fund its growth; its negative free cash flow. First, we'll determine its cash runway by comparing its cash burn with its cash reserves.Does vTv Therapeutics Have A Long Cash Runway?vTv Therapeutics' cash burn of US$23m is about 45% of its US$52m market capitalisation. From this perspective, it seems that","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/were-keeping-eye-vtv-therapeutics-123643670.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BGHQF748.EUR","TSYW.SI","VTVT","SQQQ","MNQmain","NVIW.SI","QLD","BK4112","TQQQ","QID","USJW.SI","USAW.SI","NDAQ","IE00B64PRP62.GBP","BK4139","BK4585","BK4588","LU2210150020.SGD","LU2210149790.SGD","NQmain","PSQ","LU2095319765.USD","IE00BKPKM429.USD",".IXIC","IE00B3QW5Z07.USD"],"gpt_icon":1},{"id":"2490294987","title":"vTv Therapeutics initiated with a Buy at Alliance Global Partners","url":"https://stock-news.laohu8.com/highlight/detail?id=2490294987","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490294987?lang=en_us&edition=fundamental","pubTime":"2024-12-09 20:36","pubTimestamp":1733747784,"startTime":"0","endTime":"0","summary":"Alliance Global Partners analyst James Molloy initiated coverage of vTv Therapeutics (VTVT) with a Buy rating and $35 price target vTv is a clinica...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/vtv-therapeutics-initiated-with-a-buy-at-alliance-global-partners?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/vtv-therapeutics-initiated-with-a-buy-at-alliance-global-partners?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VTVT","BK4139"],"gpt_icon":0},{"id":"2490729610","title":"Cantex Pharmaceuticals Receives FDA Orphan Drug Designation for Azeliragon for the Treatment of Brain Metastasis From Breast Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2490729610","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490729610?lang=en_us&edition=fundamental","pubTime":"2024-12-09 20:33","pubTimestamp":1733747582,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241209:nTUA4QFQYR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["VTVT","BK4139"],"gpt_icon":0},{"id":"2490724229","title":"CANTEX PHARMACEUTICALS RECEIVES FDA ORPHAN DRUG DESIGNATION FOR AZELIRAGON FOR THE TREATMENT OF BRAIN METASTASIS FROM BREAST CANCER","url":"https://stock-news.laohu8.com/highlight/detail?id=2490724229","media":"PR Newswire","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490724229?lang=en_us&edition=fundamental","pubTime":"2024-12-09 20:33","pubTimestamp":1733747580,"startTime":"0","endTime":"0","summary":"WESTON, Fla., Dec. 9, 2024 /PRNewswire/ -- Cantex Pharmaceuticals, Inc., a clinical-stage pharmaceutical company focused on developing transformative therapies for cancer and other life-threatening medical conditions, announced today that the U.S. Food and Drug Administration  granted Orphan Drug Designation to Cantex's azeliragon for the treatment of brain metastasis from breast cancer. This new azeliragon designation adds to azeliragon's two other Orphan Drug Designations for the treatment of pancreatic cancer and glioblastoma, received in mid-2024 and early 2023, respectively.\"Receiving FDA Orphan Drug Designation for azeliragon for the treatment of brain metastasis from breast cancer highlights a continued need for new treatment options for these patients,\" commented Stephen G. Marcus, M.D., Chief Executive Officer of Cantex. \"This designation reflects our continued commitment to developing new azeliragon treatment options for patients with life-threatening cancer.\". In addition to","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/HXT9jUN9ExWzYJDu4JZHww--~B/aD0xNjE7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/da286c53b030ba519a74b40ffe373e9c","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/HXT9jUN9ExWzYJDu4JZHww--~B/aD0xNjE7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/da286c53b030ba519a74b40ffe373e9c"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/cantex-pharmaceuticals-receives-fda-orphan-123300855.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cantex-pharmaceuticals-receives-fda-orphan-123300855.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["FOR","DRUG","VTVT","BK4024","BK4139"],"gpt_icon":0},{"id":"2490726265","title":"vTv Therapeutics Inc : Alliance Global Partners Initiates Coverage With Buy Rating; Target Price $35","url":"https://stock-news.laohu8.com/highlight/detail?id=2490726265","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490726265?lang=en_us&edition=fundamental","pubTime":"2024-12-09 20:19","pubTimestamp":1733746754,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241209:nFWN3NA14B:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["VTVT","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":2,"pageCount":1,"totalSize":26}]}}