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Right-sizing commercial efforts to optimize XOLREMDI promotion and support U.S. WHIM syndrome community. Restructuring impact expected to extend cash runway into first half of 2026. Reducing overall headcount by 43 people , which includes discontinuing research efforts and closing the company’s facility in Vienna, Austria, as well as pausing pre-clinical drug candidate programs;About X4 PharmaceuticalsX4 is delivering progress for patients by developing and commercializing innovative therapies for those with rare diseases of the immune system and significant unmet needs. Leveraging expertise in CXCR4 and immune system biology, X4 has successfully developed mavorixafor, an orally available CXCR4 antagonist that is currently being marketed in the U.S. as XOLREMDI in its first indication. 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