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Aptevo Therapeutics

0.9981
-0.1619-13.96%
Volume:272.03K
Turnover:280.39K
Market Cap:1.46M
PE:-0.01
High:1.18
Open:1.11
Low:0.9423
Close:1.16
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Company Profile

Company Name:
Aptevo Therapeutics
Exchange:
NASDAQ
Establishment Date:
2016
Employees:
37
Office Location:
2401 4th Avenue,Suite 1050,Seattle,Washington,United States
Zip Code:
98121
Fax:
206 838 0503
Introduction:
Aptevo Therapeutics Inc., a clinical-stage biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company's lead clinical candidates are APVO436, a bispecific T-cell engaging antibody candidate that is in Phase 1b clinical trial for acute myelogenous leukemia and myelodysplastic syndromes; and. ALG.APV-527, an investigational bispecific ADAPTIR candidate that features a mechanism of action to target 4-1BB (CD137) and 5T4, a tumor antigen expressed in various types of cancers. Its preclinical candidates include APVO603, a dual agonist bispecific antibody to target 4-1BB and OX40; APVO711, a dual mechanism bispecific ADAPTIR candidate designed to provide synergistic stimulation of CD40 on antigen presenting cells; and APVO442, a bispecific candidate based on the ADAPTIR-FLEX platform technology to enhance biodistribution of drugs to PSMA positive tumors for treatment of prostate cancer. The company has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.

Directors

Name
Position
Fuad El Hibri
Chairman
Marvin L. White
Director, Chief Executive Officer
John E. Niederhuber
Lead Independent Director
Barbara Lopez Kunz
Director
Daniel J. Abdun Nabi
Director
Grady Grant, III
Director
Zsolt Harsanyi
Director

Shareholders

Name
Position
Marvin L. White
Director, Chief Executive Officer
Jane Gross
Senior Vice President and Chief Scientific Officer
Jeffrey G. Lamothe
Senior Vice President and Chief Financial Officer
Randy J. Maddux
Senior Vice President of Operations
Scott C. Stromatt
Senior Vice President and Chief Medical Officer