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PHOENIX, Feb. 14, 2025  -- Creative Medical Technology Holdings, Inc.  , a pioneering biotechnology firm specializing in regenerative medicine solutions for immunotherapy, endocrinology, urology, gynecology, and orthopedics, today announced compelling mid-term follow-up data from its StemSpine pilot study utilizing its AlloStem cells for the treatment of chronic lower back pain.The pilot study demonstrated a substantial reduction in opioid dependency and significant improvements in pain levels and functional mobility. Notably, over 90% of patients reported no opioid use for pain management three years post-procedure, with an 80% persistent reduction in pain scores and a greater than 60% improvement in Oswestry Disability Index scores. Only one patient required reintervention at the three-year follow-up mark, and no serious adverse events were reported, reinforcing the favorable safety profile of the StemSpine procedure.Forwa","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/creative-medical-technology-holdings-announces-120000449.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Creative Medical Technology Holdings Announces Mid-Term Follow-up Study Data Reporting Significant Reduction in Opioid Use by Chronic Lower Back Pain Patients Undergoing StemSpine® Procedure using AlloStem™","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2510938751","title":"Creative Medical Technology reports one-year results for AlloStem program","url":"https://stock-news.laohu8.com/highlight/detail?id=2510938751","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510938751?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:30","pubTimestamp":1739284253,"startTime":"0","endTime":"0","summary":"Creative Medical Technology (CELZ) announced one-year follow-up data from the AlloStem Type 2 Diabetes pilot study for late-stage patients. CELZ-20...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/creative-medical-technology-reports-one-year-results-for-allostem-program?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/creative-medical-technology-reports-one-year-results-for-allostem-program?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2510382424","title":"Creative Medical Technology Holdings Inc - Announces Promising One-Year Data From Allostem Type 2 Diabetes Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2510382424","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510382424?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:27","pubTimestamp":1739284039,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250211:nFWN3P211K:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2510382420","title":"Creative Medical Technology Holdings Inc - Celz-201 Achieves 80% Efficacy in Reducing Insulin Dependency","url":"https://stock-news.laohu8.com/highlight/detail?id=2510382420","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510382420?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:27","pubTimestamp":1739284039,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250211:nFWN3P211K:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["CELZ","BK4139"],"gpt_icon":0},{"id":"2510387248","title":"Creative Medical Technology Reports Positive One-Year Results for AlloStem™ Type 2 Diabetes Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2510387248","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510387248?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:25","pubTimestamp":1739283900,"startTime":"0","endTime":"0","summary":"Significant Efficacy and No Serious Adverse Effects Observed with CELZ-201. PHOENIX, Feb. 11, 2025  -- Creative Medical Technology Holdings, Inc. , a clinical-stage biotechnology company advancing regenerative medicine solutions, today announced promising one-year follow-up data from the AlloStem   Type 2 Diabetes pilot study for late-stage patients. CELZ-201 is an off the shelf, ready-to-use universal and proprietary allogenic  cell line developed by the Company.Results demonstrate that CELZ-201 achieved an 80% overall efficacy rate in reducing insulin dependency and stabilizing hemoglobin A1c levels, with no serious adverse effects reported.The study, which included 20 patients—10 receiving CELZ-201 and 10 undergoing optimized medical therapy—validated the safety and efficacy of CELZ-201 through the same infusion procedure used in the Company’s U.S. FDA-cleared Type 1 Diabetes clinical trial, which is currently underway. The absence of safety concerns further supports the potential o","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/creative-medical-technology-reports-positive-142500212.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CELZ","BK4139"],"gpt_icon":0},{"id":"2509051285","title":"Creative Medical Technology expands collaboration with Greenstone Biosciences","url":"https://stock-news.laohu8.com/highlight/detail?id=2509051285","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509051285?lang=en_us&edition=fundamental","pubTime":"2025-02-05 21:30","pubTimestamp":1738762223,"startTime":"0","endTime":"0","summary":"Creative Medical Technology (CELZ) announced an expanded agreement with Greenstone Biosciences to leverage Artificial Intelligence in further devel...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/creative-medical-technology-expands-collaboration-with-greenstone-biosciences?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/creative-medical-technology-expands-collaboration-with-greenstone-biosciences?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["CELZ","BK4139"],"gpt_icon":0},{"id":"2509285288","title":"Creative Medical Technology Holdings Expands Collaboration With Greenstone Biosciences to Accelerate Ipscelz Pipeline Development","url":"https://stock-news.laohu8.com/highlight/detail?id=2509285288","media":"THOMSON REUTERS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509285288?lang=en_us&edition=fundamental","pubTime":"2025-02-05 21:25","pubTimestamp":1738761900,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250205:nTUA6NJLJX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2509286407","title":"Creative Medical Technology Holdings Expands Collaboration with Greenstone Biosciences to Accelerate iPSCelz Pipeline Development","url":"https://stock-news.laohu8.com/highlight/detail?id=2509286407","media":"GlobeNewswire","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509286407?lang=en_us&edition=fundamental","pubTime":"2025-02-05 21:25","pubTimestamp":1738761900,"startTime":"0","endTime":"0","summary":"PHOENIX, Feb. 05, 2025  -- Creative Medical Technology Holdings, Inc.  , a clinical-stage biotechnology company advancing regenerative medicine solutions, today announced an expanded agreement with Greenstone Biosciences Inc.  to leverage Artificial Intelligence  in further developing its human induced pluripotent stem cell  platform for diabetes treatment.Advancing Multi-Gene Edited Hypoimmune iPSCsThe next phase of development focuses on multi-gene edited hypoimmune iPSCs—cells engineered with precise modifications to evade immune detection, improve survival, and optimize therapeutic potential. These cutting-edge advancements offer the potential to eliminate the need for immunosuppression, significantly improving patient outcomes in cell-based regenerative therapies.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/creative-medical-technology-holdings-expands-132500175.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["AAQC","CELZ","BK4139"],"gpt_icon":0},{"id":"2507621421","title":"Creative Medical reports data from first cohort in Phase 1/2 CELZ-201-DDT trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2507621421","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507621421?lang=en_us&edition=fundamental","pubTime":"2025-01-30 22:30","pubTimestamp":1738247437,"startTime":"0","endTime":"0","summary":"Creative Medical Technology (CELZ) announced initial data from the first cohort of its ongoing Phase 1/2 clinical trial of CELZ-201-DDT, the Compan...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/creative-medical-reports-data-from-first-cohort-in-phase-1-2-celz-201-ddt-trial?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/creative-medical-reports-data-from-first-cohort-in-phase-1-2-celz-201-ddt-trial?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["DDT","CELZ","BK4139"],"gpt_icon":0},{"id":"2507629532","title":"Creative Medical Technology Holdings Announces Positive Initial Safety, Tolerability, and Efficacy Data From First Cohort in Phase 1/2 Trial of Celz-201-Ddt for Chronic Back Pain","url":"https://stock-news.laohu8.com/highlight/detail?id=2507629532","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507629532?lang=en_us&edition=fundamental","pubTime":"2025-01-30 22:25","pubTimestamp":1738247100,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250130:nTUABRTXL6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2507621819","title":"Creative Medical Technology Holdings Announces Positive Initial Safety, Tolerability, and Efficacy Data from First Cohort in Phase 1/2 Trial of CELZ-201-DDT for Chronic Back Pain","url":"https://stock-news.laohu8.com/highlight/detail?id=2507621819","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507621819?lang=en_us&edition=fundamental","pubTime":"2025-01-30 22:25","pubTimestamp":1738247100,"startTime":"0","endTime":"0","summary":"PHOENIX, Jan. 30, 2025  -- Creative Medical Technology Holdings, Inc. , a clinical-stage biotechnology company focused on regenerative medicine, today announced promising initial data from the first cohort of its ongoing Phase 1/2 clinical trial of CELZ-201-DDT, the Company’s proprietary stem cell-based therapeutic for the treatment of chronic back pain caused by degenerative disc disease .The first cohort of 10 participants  completed the study phase without any dose-limiting toxicities or serious adverse events. Blinded preliminary data suggest encouraging therapeutic potential in alleviating back pain and restoring functionality. Following a comprehensive safety review, the independent Data Safety Monitoring Board  recommended the trial proceed to the next cohort as planned.Safety Confirmed: CELZ-201-DDT demonstrated an excellent safety profile, with no serious adverse events reported in the first cohort.About CELZ-201-DDTCELZ-201-DDT is a proprietary regenerative stem cell-based th","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/creative-medical-technology-holdings-announces-142500258.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4170","BK4139","BK4585","CELZ","DDD","BK4551","BK4161","BK4588","BK4546","DDT"],"gpt_icon":0},{"id":"2483830209","title":"Creative Medical Gets Safety Approval in FDA-Cleared Back Pain Treatment Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2483830209","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483830209?lang=en_us&edition=fundamental","pubTime":"2024-11-14 00:03","pubTimestamp":1731513780,"startTime":"0","endTime":"0","summary":"Creative Medical Technology  said Wednesday its experimental treatment for chronic lower back pain due to degenerative disc disease, CELZ-201, successfully passed an independent interim safety review by the Data Safety Monitoring Board in its clinical trial.The clearance to proceed with the ADAPT clinical trial, which will evaluate the safety, tolerability and efficacy of CELZ-201, was granted after a safety data review from the first five dosed patients, according to the company.The experimental drug will be administered intramuscularly and will be compared to placebo in the double-blind, dose-escalation study, Creative Medical added.Shares of Creative Medical Technology were up 1.1% in recent trading.Price: 2.79, Change: +0.03, Percent Change: +1.09","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CELZ","BK4139"],"gpt_icon":0},{"id":"2483688622","title":"Creative Medical advances FDA cleared ADAPT trial with independent review","url":"https://stock-news.laohu8.com/highlight/detail?id=2483688622","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483688622?lang=en_us&edition=fundamental","pubTime":"2024-11-13 22:11","pubTimestamp":1731507078,"startTime":"0","endTime":"0","summary":"Creative Medical Technology (CELZ) announces the successful completion of an independent interim safety review by the Data Safety Monitoring Board,...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/creative-medical-advances-fda-cleared-adapt-trial-with-independent-review?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/creative-medical-advances-fda-cleared-adapt-trial-with-independent-review?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","CELZ"],"gpt_icon":0},{"id":"2483988516","title":"BRIEF-Creative Medical Technology Holdings, Inc. Advances FDA Cleared Adapt Clinical Trial With Positive Independent Review, Validating The Safety And Potential Of CELZ-201 For Chronic Lower Back Pain Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2483988516","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483988516?lang=en_us&edition=fundamental","pubTime":"2024-11-13 22:07","pubTimestamp":1731506869,"startTime":"0","endTime":"0","summary":"Nov 13  - Creative Medical Technology Holdings Inc   :   * CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. ADVANCES FDA CLEARED ADAPT CLINICAL TRIAL WITH POSITIVE INDEPENDENT REVIEW, VALIDATING THE SAFETY AND POTENTIAL OF CELZ-201 FOR CHRONIC LOWER BACK PAIN TREATMENTSource text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELZ","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":2,"pageCount":1,"totalSize":29}]}}