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J&J’s JNJ bankruptcy strategy to settle talc lawsuits failed for the third time. The European Commission approved Pfizer’s PFE respiratory syncytial virus vaccine, Abrysvo, for use in adults aged 18 through 59 years.Here's a recap of the week’s most important stories.Texas Court Rejects J&J’s Bankruptcy Attempt to End Talc Suits. A bankruptcy court in Texas rejected J&J’s proposed bankruptcy plan to settle claims related to its talc lawsuits for the third time. In September, J&J, via a subsidiary called Red River Talc, filed for voluntary bankruptcy in the Southern District of Texas after it received the support of around 83% of current claimants for the proposed bankruptcy plan, which was above the 75% required by the U.S. bankruptcy","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pharma-stock-roundup-fda-nod-134600557.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2112291526.USD","LU0985320562.USD","IE00BSNM7G36.USD","LU1674673691.USD","SG9999013999.USD","LU0320765992.SGD","BK4533","LU2129689431.USD","LU0345770308.USD","IE00BVYPNW00.USD","LU0306807586.USD","LU0868494617.USD","JNJ","AZN","LU2129689605.HKD","LU0345770993.USD","LU2430703178.SGD","PFE","IE00B2B36J28.USD","LU1244550221.USD","IE00BLSP4239.USD","LU1430594728.SGD","LU0889566641.SGD","IE00B1BXHZ80.USD","LU0070302665.USD","LU1261432733.SGD","BK4532","LU0912757837.SGD","BK4599","SNY","SG9999001176.USD","LU2602419157.SGD","CHMP","LU2592432038.USD","IE00B3PB1722.GBP","BK4585","SG9999001440.SGD","LU2133065610.SGD","LU1732799900.SGD","LU0114720955.EUR","LU0058720904.USD","LU1280957306.USD","LU0289739699.SGD","LU1267930813.SGD","IE00BJT1NW94.SGD","NVS","LU0225284248.USD","LU1894683264.USD","LU1778281490.HKD","LU1585245621.USD"],"gpt_icon":1},{"id":"2524293880","title":"Novartis Secures Third FDA Approval For Its Kidney Disease Portfolio In One Year","url":"https://stock-news.laohu8.com/highlight/detail?id=2524293880","media":"Benzinga","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524293880?lang=en_us&edition=fundamental","pubTime":"2025-04-04 00:10","pubTimestamp":1743696643,"startTime":"0","endTime":"0","summary":"The U.S. Food and Drug Administration  on Wednesday granted accelerated approval for Novartis AG’s  Vanrafia  to reduce proteinuria in adults with primary immunoglobulin A nephropathy  at risk of rapid disease progression.Vanrafia is a once-daily, non-steroidal, oral treatment that can be added to supportive care, including a renin-angiotensin system inhibitor with or without a sodium-glucose co-transporter-2 inhibitor.Vanrafia was granted accelerated approval based on a prespecified interim analysis of the Phase 3 ALIGN study measuring the reduction of proteinuria at 36 weeks compared to placebo.Also Read: FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals. It has not been established whether Vanrafia slows kidney function decline in patients with IgAN.The continued approval of Vanrafia may be contingent upon verifying clinical benefit from the ongoing Phase 3 ALIGN study evaluating whether Vanrafia slows disease progression as measured by estimated glomerular filtration rat","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/novartis-secures-third-fda-approval-161043441.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Novartis Secures Third FDA Approval For Its Kidney Disease Portfolio In One Year","news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0208291251.USD","IE00B2B36J28.USD","IE00B4R5TH58.HKD","LU0070302665.USD","BK4578","IE00BJJMRZ35.SGD","LU0211331839.USD","BK4532","NVS","BK4585","BK4588","BK4007","IE0002141913.USD","LU0320765489.SGD","IE00BFTCPJ56.SGD","IE00BJT1NW94.SGD","IE0009355771.USD"],"gpt_icon":0},{"id":"2524128499","title":"Novartis Gets FDA Accelerated Approval for Vanrafia","url":"https://stock-news.laohu8.com/highlight/detail?id=2524128499","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524128499?lang=en_us&edition=fundamental","pubTime":"2025-04-03 16:41","pubTimestamp":1743669711,"startTime":"0","endTime":"0","summary":"Novartis  said late Wednesday the US Food and Drug Administration granted accelerated approval for Vanrafia to reduce proteinuria in adults with primary immunoglobulin A nephropathy, or IgAN, at risk of rapid disease progression.IgAN is a progressive, rare kidney disease.Data from an ongoing phase III showed that Vanrafia achieved proteinuria reduction of about 36%, compared with placebo, with improvements seen at week six and sustained through week 36, as well as favorable safety, the company said.It has not been established whether Vanrafia slows kidney function decline in patients with IgAN, the company said, adding that the continued approval could depend on longer term data from the ongoing phase III study, which will evaluate whether Vanrafia slows disease progression based on estimated glomerular filtration rate decline, with results expected in 2026.Novartis shares were up 1.3% in recent premarket activity Thursday.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4578","BK4585","LU0070302665.USD","IE00B4R5TH58.HKD","LU0208291251.USD","BK4007","BK4532","IE00BJT1NW94.SGD","NVS","IE00B2B36J28.USD","LU0320765489.SGD","IE00BJJMRZ35.SGD","LU0211331839.USD","IE0002141913.USD","BK4588","IE0009355771.USD","IE00BFTCPJ56.SGD"],"gpt_icon":0},{"id":"2524832162","title":"Big Pharma Stocks Rise After Exclusion From U.S. Tariffs -- Market Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2524832162","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524832162?lang=en_us&edition=fundamental","pubTime":"2025-04-03 15:51","pubTimestamp":1743666660,"startTime":"0","endTime":"0","summary":"0751 GMT - Big Pharma stocks are up after U.S. President Trump exempted pharmaceuticals for now from his reciprocal tariffs on global imports. \"It is still somewhat unclear whether the broader reaching 10% baseline tariffs could still be levied against imported drugs and vaccines, in our view,\" Shore Capital analyst Sean Conroy says in a note. Likewise, Bryan Garnier Research analysts say in a note that the pharma industry is left uncertain about an actual tariff risk given Trump's mixed remarks that drugmakers \"will come roaring back to the U.S., because if they don't, they got a big tax to pay.\" Novartis and Sanofi are up 0.6% and 0.3%, respectively. The U.K's AstraZeneca and GSK rose 1% and 1.6%, respectively. Swiss pharma giant Roche is down 2.3% after its multiple-sclerosis drug Ocrevus failed to meet its primary endpoint. 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